Magnetic cleaning and separating device and method for chemiluminescence immunity analyzer

Abstract

The invention is applicable to the technical field of automatic biochemical analysis, and provides a magnetic cleaning and separating device for a chemiluminescence immunity analyzer. The magnetic cleaning and separating device comprises a rack and a mounting plate mounted on the rack, a central rotating disc, a cleaning assembly, a separation assembly and a uniform mixing assembly; the central rotating disc is arranged on the mounting plate and can rotate in the circumferential direction relative to the mounting plate; a bearing hole for bearing a reaction cup is formed in the central rotating disc; the cleaning assembly is used for performing liquid injection and liquid suction on the reaction cup; the separation assembly is used for adsorbing the uniformly mixed magnetic beads in the reaction cup; the uniform mixing assembly comprises a sealing mechanism and a uniform mixing mechanism; the uniform mixing mechanism is used for driving the reaction cup to rotate; and when the reaction cup rotates, the sealing mechanism is used for blocking the open end of the reaction cup; According to the magnetic cleaning and separating device, the uniform mixing mechanism is optimized, the uniform mixing efficiency is improved, the cleaning effect of the magnetic beads in the reaction cup is ensured, and the test efficiency of subsequent tests and the accuracy of test results are ensured.

Description

technical field [0001] The invention relates to the technical field of automated biochemical analysis, in particular to a magnetic cleaning and separation device and method for a chemiluminescence immunoassay analyzer. Background technique [0002] In the automatic chemiluminescence immunoassay analyzer, magnetic beads refer to colloidal composite materials that can be uniformly dispersed in a certain base liquid. Because of its superparamagnetic properties, high specific surface area, and functional groups that can be modified. Therefore, antigens / antibodies, enzymes, nucleic acids / oligonucleotides, small molecule drugs, etc. are immobilized on its surface. The magnetic separation technology is to separate the magnetic beads and the reaction liquid for solid-liquid phase separation. In order to ensure the effect of magnetic separation, it is necessary to fully mix the reaction solution during the separation process, inject and absorb liquid and wash repeatedly to remove i...

AI Technical Summary

Problems solved by technology

As a result, the structural design of the reaction liquid cleaning mechanism is complicated, the degree of automation is not high, the mixing efficiency is not high, and the cleaning effect is not good, which affects the test efficiency and accuracy of the test results of the back-end detection

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