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Pharmaceutical packages with coatings comprising polysilazane

A polysilazane and packaging technology, which is used in pharmaceutical packaging, special packaging objects, packaging, etc., can solve the problems of easy glass breakage and ineffective tolerance.

Pending Publication Date: 2021-12-10
CORNING INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] However, while the aforementioned tempering techniques improve the ability of strengthened glass to withstand blunt impact, these techniques are less effective at improving the glass's resistance to abrasion (such as scratching) that may occur during manufacturing, shipping, and handling
These defects may make the glass more susceptible to breakage

Method used

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  • Pharmaceutical packages with coatings comprising polysilazane
  • Pharmaceutical packages with coatings comprising polysilazane
  • Pharmaceutical packages with coatings comprising polysilazane

Examples

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Embodiment 1

[0095] Glass vials (compositionally ion-exchanged alkali metal aluminosilicates) were coated with a mixed polysilazane coating comprising silazane, siloxane, and silane. Specifically, vials were coated and tested using three commercially available polysilazane solutions: HS-900, HS-907, and HS-908 (each from Huntington Specialty Materials). To coat the vials, heat uncoated vials at 320°C for 20 minutes and then return to room temperature. HS-900, HS-907 and HS-908 solutions can be used in the form provided commercially without the addition of additional solvents. The paint was applied to the outside of the vial by dip coating with a dipping speed of 10 mm / s, a hold time of 5 s, and a return speed of 2 mm / s. After impregnation, the vials were kept at room temperature for 1 hour and then cured in an oven at 250° C. (without added moisture) for 30 minutes.

[0096] It should be noted that many conventional polysilazane curing processes use steam curing, but in this example a dr...

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Abstract

The present disclosure is directed to pharmaceutical packages that include a coating that comprises polysilazane, and methods for the production of such. In one or more embodiments of the present disclosure, a pharmaceutical package may include a glass container comprising a first surface and a second surface opposite the first surface. The first surface may be an outer surface of the glass container. The pharmaceutical package may further include a coating positioned over at least a portion of the first surface of the glass container. The coating may include polysilazane.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of priority under 35 U.S.C §120 to U.S. Provisional Application Serial No. 62 / 841,446, filed May 1, 2019, which is based upon the contents of that application and is incorporated herein by reference in its entirety. [0003] background technical field [0004] This specification relates generally to glass articles, and more particularly to coated glass articles, such as pharmaceutical packaging. Background technique [0005] Historically, glass has been used as the material of choice for packaging pharmaceuticals due to its airtightness, optical clarity and superior chemical durability relative to other materials. In particular, glass used in pharmaceutical packaging needs to be sufficiently chemically durable without affecting the stability of the pharmaceutical composition contained therein. Glasses with suitable chemical durability for many pharmaceutical applications include th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B65D23/08C03C17/30
CPCB65D23/08C03C17/30C03C17/005B65D1/0215B65D23/0821A61J1/065A61J1/1468C03C2217/78
Inventor T·F·阿里奎邓华云R·A·海耶斯K·R·姆卡蒂钮渭钧F·C·瓦格纳
Owner CORNING INC