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Method for predicting relapse of cerebral arterial thrombosis

A technology of ischemic stroke and prediction method, which is applied in the direction of neural learning method, instrument, biological neural network model, etc., can solve the problem of unbalanced data filling sample imbalance, few recurrence prediction studies, non-imaging data and hospitalization structure to achieve the effects of high accuracy, strong mining ability, and strong extraction ability

Pending Publication Date: 2021-12-17
THE SECOND AFFILIATED HOSPITAL TO NANCHANG UNIV
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AI Technical Summary

Problems solved by technology

But there is still no general method that can be applied to solve the medical prediction problem
Moreover, there are relatively few studies on the prediction of recurrence after discharge of ischemic stroke patients. In this research field, researchers have not conducted research on data filling of ischemic stroke data gaps and sample imbalance. Second, researchers have not Fusion of imaging data and inpatient structured feature data to build a model

Method used

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  • Method for predicting relapse of cerebral arterial thrombosis
  • Method for predicting relapse of cerebral arterial thrombosis
  • Method for predicting relapse of cerebral arterial thrombosis

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Experimental program
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Effect test

Embodiment

[0069] (1) The hospitalization records of 2,817 patients with ischemic stroke were collected from the prospective cohort of the Medical Big Data Research Center, and all of these patients were confirmed to be ischemic stroke by MRI. The data are roughly divided into: demographic information (gender, age, marriage), inpatient laboratory test data, structured data after inpatient electronic medical records, and imaging data.

[0070] (2) Analyzing the distribution of all samples in the follow-up records of the following year, 326 relapsed and 2491 non-relapsed, the relapse rate was about 13.08%, and there was an extreme sample imbalance. There are 163 people in the non-relapse group who have previous hospitalization information, so the latest hospitalization information is used to fill in the blank value of this part of patients.

[0071] (3) Sequentially calculate the correlation between the data structured features and whether the dependent variable recurs, and select the feat...

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Abstract

The invention provides a method for predicting relapse of cerebral arterial thrombosis, which comprises the following steps of: firstly, multi-dimensional data of a patient are extracted for fusion, Lasso analysis is performed on the fused data, and key factors are output; secondly, vacancy values in the data set are filled, and three different modes are adopted for filling of patients which do not relapse and have hospitalization histories, features which have large missing quantities of the patients which have no hospitalization histories and features which have small missing quantities of the patients which have no hospitalization histories; the sample imbalance existing in the data set is processed by adopting a sample imbalance processing mode; meanwhile, CT image data of the brain of a patient are taken, convolutional learning is conducted on the image data through a GCForest multi-granularity scanning layer, and features are normalized to be in the size of [32, 1] through feature remodeling; the remodeled features are taken as fixed features and structured features, the fixed features and the structured features are jointly transmitted to a GCForest multi-granularity scanning layer for feature enhancement, and the features are finally transmitted to a cascade forest for model training. A new thought is provided for application of the artificial intelligence technology in medical treatment.

Description

technical field [0001] The invention relates to the technical field of ischemic stroke recurrence prediction, in particular to a method for ischemic stroke recurrence prediction. Background technique [0002] Stroke is the leading cause of death and disability in my country, with a recurrence rate as high as 14.7%. The risk of death and disability after recurrence of ischemic stroke is 9.4 times that of the first stroke. Recurrence risk prediction helps to identify high-risk groups for stroke recurrence, and provides decision-making information support for three-early prevention. There are three main types of current medical prediction technology: one is traditional machine learning algorithms, such as: Logistic regression, SVM, decision tree, etc.; the other is deep neural network, such as: multi-layer perceptron MLP, LSTM, GRU, etc.; Another category is integrated algorithms, such as: random forest, Adboost, Xgboost, etc. Appeal Medical prediction methods and techniques ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/30G06K9/62G06N3/04G06N3/08
CPCG16H50/30G06N3/08G06N3/045G06F18/23213G06F18/22G06F18/253Y02A90/10
Inventor 易应萍程学新祝新根邵江华刘建模罗颢文俞鹏飞
Owner THE SECOND AFFILIATED HOSPITAL TO NANCHANG UNIV
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