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PCR microfluidic temperature control device

A temperature control device and microfluidic technology, which is applied in the field of microfluidics, can solve problems such as uneven heating, wear on the surface of the disc, and difficulty in ensuring temperature control, so as to reduce heat loss and increase the heating and cooling rate.

Pending Publication Date: 2021-12-24
ZYBIO INC
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In the related art, the heating block and the reagent disk are usually arranged in a relatively rotating structure, which causes sliding friction between the heating block and the reagent disk, wears the surface of the disk, and affects the accuracy of optical detection. At the same time, air heat transfer is used, resulting in poor heating. Uniformity, the temperature in different areas cannot be reached quickly, making it difficult to ensure temperature control

Method used

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  • PCR microfluidic temperature control device
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  • PCR microfluidic temperature control device

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Embodiment Construction

[0053]The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention.

[0054] It should be noted that all directional indications (such as up, down, left, right, front, back...) in the embodiments of the present invention are only used to explain the relationship between the components in a certain posture (as shown in the accompanying drawings). Relative positional relationship, movement conditions, etc., if the specific posture changes, the directional indication will also change accordingly.

[0055] At the same time, ...

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Abstract

The invention discloses a PCR microfluidic temperature control device. The PCR microfluidic temperature control device comprises a machine body, a heating assembly and a lifting assembly, wherein the machine body is provided with a mounting space, the heating assembly comprises a heating table and a pressing plate, the pressing plate and the heating table are movably arranged in the mounting space and are oppositely arranged, the heating table is used for containing and heating reagent cards, and the lifting assembly is connected with the heating table and / or the pressing plate to drive the heating table and / or the pressing plate, so that the heating table and the pressing plate get close to each other or get away from each other to press or release the reagent cards. The invention aims to provide the PCR microfluidic temperature control device which is low in heat loss, high in heating and cooling speed and simple in structure, and the PCR microfluidic temperature control device effectively reduces the heat loss, realizes the attaching degree of the amplification area of a reagent disc and a heat conducting plate, and improves the heating and cooling speed of the reagent disc.

Description

technical field [0001] The invention relates to the field of microfluidic technology, in particular to a PCR microfluidic temperature control device. Background technique [0002] Polymerase chain reaction is referred to as PCR (Polymerase Chain Reaction). PCR is a method for enzymatically synthesizing specific DNA fragments in vitro. Periodic cycle treatment is carried out through steps such as heating at different temperatures, and then the target DNA can be rapidly amplified. PCR has the characteristics of strong specificity, high sensitivity, easy operation, and time-saving; it can not only be used for basic research such as gene isolation, cloning, and nucleic acid sequence analysis, but also for disease diagnosis. [0003] Microfluidics refers to the manipulation of liquids on the submillimeter scale, generally in the range of a few microns to hundreds of microns. Microfluidics integrates the basic operating units involved in the fields of biology and chemistry, and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/38C12M1/00C12M1/34
CPCB01L3/5027B01L7/00B01L2200/027B01L2200/10
Inventor 阳交凤
Owner ZYBIO INC
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