Unlock instant, AI-driven research and patent intelligence for your innovation.

Application of zinc gluconate in preparation of Bacteroides regulator

A technology of zinc gluconate and Bacteroides, which is applied in the field of medicine to achieve the effect of increasing abundance and promoting mass proliferation

Pending Publication Date: 2022-01-14
MEI YI TIAN BIOLOGICAL MEDICINE WUHAN CO LTD
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no relevant report on the regulatory effect of zinc gluconate on the intestinal probiotic Bacteroides

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of zinc gluconate in preparation of Bacteroides regulator
  • Application of zinc gluconate in preparation of Bacteroides regulator
  • Application of zinc gluconate in preparation of Bacteroides regulator

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Since the intestinal flora derived from the human body cannot completely colonize the mice, human feces were taken as intestinal flora samples, and in vivo simulation experiments were carried out in vitro to observe the effect of zinc gluconate intervention on Bacteroides Adjustment, the specific operation process is as follows:

[0019] 1. Fecal sample processing

[0020] (1) PBS buffer preparation

[0021] Taking 1000ml as an example, weigh the following medicines with an electronic analytical balance and make records, and pour them into a 1000ml beaker, including: KH 2 PO 4 0.24g, Na 2 HPO 4 12H 2 O 2.90g, NaCl 8.00g, KCl 0.20g.

[0022] Use a graduated cylinder to measure 800ml of ultra-pure water and pour it into a beaker, put it into the stirring rotor, and put it on a magnetic heating stirrer to stir until it is completely dissolved, then use a calibrated pH meter to measure the pH of the above solution, use 0.1M HCl or NaOH adjusted pH=7.4±0.05.

[0023...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses application of zinc gluconate in preparation of a Bacteroides regulator. Through a zinc gluconate intervention experiment, the effect of the zinc gluconate for regulating probiotics Bacteroides is found and verified for the first time, and the abundance of the Bacteroides can be remarkably increased, so that the zinc gluconate can be prepared into a corresponding regulating medicine for preventing and / or treating intestinal flora disturbance and assisting in treating diseases such as inflammatory bowel diseases, colon cancer and autism related to the Bacteroides, and has important significance for maintaining the stability of intestinal flora and assisting in treating related diseases caused by the flora disturbance. Meanwhile, the zinc gluconate is used for promoting the Bacteroides to proliferate in large quantity in vitro, so that the Bacteroides can be cultured in large scale in vitro to prepare a microbial agent.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to the application of zinc gluconate in preparing a Bacteroides regulator. Background technique [0002] Intestinal microorganisms refer to the large number of microorganisms in the human intestinal tract. These microorganisms rely on the human intestinal tract to live and help the human body to complete a variety of physiological and biochemical functions. As the largest and most complex microecosystem in the human body, gut microbes not only serve as an important bridge between diet and host, but also regulate human health by themselves and their metabolites. Intestinal flora is closely related to human health. Through dynamic physiological interactions with the host, they achieve micro-ecological balance and effectively prevent the translocation of bacteria and endotoxins in the intestine. Based on this, by changing the composition of intestinal microbial flora, it ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K33/30A61K31/191A61P1/00A61P35/00A61P25/18A23L33/10A23L33/16A23L2/52A23C9/152A23C9/16A21D2/14A21D13/06
CPCA61K33/30A61K31/191A61P1/00A61P35/00A61P25/18A23L33/10A23L33/16A23L2/52A23C9/1522A23C9/16A21D2/145A21D13/06A23V2002/00A23V2200/32A23V2250/04A23V2250/1642
Inventor 刘庆军沈鹤霄张帆李国龙熊云刘慧敏
Owner MEI YI TIAN BIOLOGICAL MEDICINE WUHAN CO LTD