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Blood treatment filter

A blood treatment and filter technology, applied in the direction of membrane filter, filtration separation, suction equipment, etc., can solve the problems of blood flow obstruction, insufficient filtration flow rate and filtration performance, strong tendency to close, etc., to achieve Excellent effect of blood recovery

Active Publication Date: 2022-02-22
ASAHI KASEI MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] That is to say, for the filter that has used the flexible container, point out that there is the following problem before: The tendency of the filter material to close to the container on the outlet side is strong due to the double force, so the flow of blood is hindered and cannot be obtained. Sufficient filtration flow rate and filtration performance
However, in particular, the balance between leukocyte removal performance and blood fluidity becomes a problem for the above reasons.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～5

[0140] As the filter constituent unit A1 and the filter constituent unit B, nonwoven fabrics produced by a melt-blown method were used. As the filter constituent unit P, a nonwoven fabric produced by a spunbond method is used.

[0141] The thickness of A1 as the filter constituent unit: 0.42 (mm), air resistance per unit thickness: 5.2 (Pa·s / m 2 ) of PBT non-woven fabric, and the thickness of B as the filter constituent unit: 0.41 (mm), air resistance per unit thickness: 10.4 (Pa·s / m 2 ) of PBT non-woven fabric, the thickness of P as a filter constituent unit: 0.20 (mm), the air resistance per unit thickness: 0.20 (Pa·s / m 2 ) of polyethylene terephthalate nonwoven fabrics were stacked in the number and order shown in Table 1 to form a laminate, which was cut into a size of 91 cm × 74 cm using a laser cutter to make a filter material.

[0142] The filter material is sandwiched between two flexible polyvinyl chloride resin sheets having a port (port) that becomes the inlet or ...

Embodiment 6～10、15、17

[0144] As filter constituent unit A1, thickness used: 0.42 (mm), air resistance per unit thickness: 7.3 (Pa·s / m 2 ) using the same method as in Example 1, except that a blood processing filter was prepared, and a leukocyte removal performance test was performed.

Embodiment 11～13

[0146] As filter constituting unit A1, use thickness: 0.42(mm), air resistance per unit thickness: 8.7(Pa·s / m 2 ) using the same method as in Example 1, except that a blood processing filter was prepared, and a leukocyte removal performance test was performed.

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Abstract

The present invention addresses the problem of providing a blood treatment filter that is excellent in all of leukocyte removal performance, filtration time (filtration speed) and blood recovery. This problem can be solved by the blood treatment filter mentioned below. The blood treatment filter comprises a flexible container having an inlet port of blood and an outlet port of blood, a filter medium disposed between the inlet port and the outlet port in the flexible container, and a flow path-securing member disposed between the filter medium and the outlet port in the flexible container, wherein: the filter medium comprises a filter layer X1 containing a filter-forming unit A1 and a filter layer Y containing a filter-forming unit B; the filter layer X1 is disposed between the filter layer Y and the flow path-securing member; the aeration resistance per thickness of the filter-forming unit A1 is 5.0 Pa.s / m<2> or more and less than 9.0 Pa.s / m<2>; the aeration resistance per thickness of the filter-forming unit B is 9.0 Pa.s / m<2> or more; the aeration resistance of the filter layer X1 is 4.0 kPa.s / m or more and not more than 20.0 kPa.s / m; and the aeration resistance of the filter medium is 55.0 kPa.s / m or more and less than 75.0 kPa.s / m.

Description

technical field [0001] The present invention relates to a blood treatment filter for removing undesirable components such as aggregates and leukocytes from liquid or blood containing blood components. [0002] In particular, the present invention relates to a blood treatment filter for removing fine aggregates and white blood cells that cause side effects from whole blood preparations for blood transfusion, red blood cell preparations, platelet preparations, plasma preparations, and the like. Background technique [0003] Whole blood collected from a donor can be used as raw materials for blood component preparations such as erythrocyte preparations, platelet preparations, and plasma preparations. However, whole blood contains undesirable components such as microaggregates and white blood cells that cause various side effects of blood transfusion. Therefore, undesired components are usually removed after blood collection and before use of blood component preparations. [00...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/02B01D39/16
CPCA61M1/02A61M1/0272A61M1/0281B01D39/16A61M1/0218B01D2239/12B01D2239/1233B01D39/1623B01D2239/10B01D2239/0622B01D2239/0627B01D2239/065A61M2202/0439
Inventor 中村和彦横沟朋久
Owner ASAHI KASEI MEDICAL CO LTD