Microfluid self-conduction wound monitoring type intelligent dressing and preparation method thereof

A microfluidic and wound technology, applied in dressings, viscous dressings, medical science, etc., can solve the problems of monitoring response continuity and low sensitivity, exudate interference monitoring, blocking continuous monitoring, etc., to avoid the influence of dressing environmental factors , improve sensitivity and avoid serious infection

Inactive Publication Date: 2022-03-01
河南驼人医疗器械研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the existing intelligent dressing technology has a certain monitoring effect on the pH of the wound environment, the continuity and sensitivity of the monitoring response are not high, and it is easily interfered by the state of the wound dressing and the environmental factors around the wound.
When the dressin

Method used

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  • Microfluid self-conduction wound monitoring type intelligent dressing and preparation method thereof
  • Microfluid self-conduction wound monitoring type intelligent dressing and preparation method thereof
  • Microfluid self-conduction wound monitoring type intelligent dressing and preparation method thereof

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preparation example Construction

[0042] The present invention also provides a preparation method of the smart dressing described in the above scheme, comprising the following steps:

[0043] a) After mixing and degassing the silica gel solution, pour it into a microchannel mold to complete vulcanization, and take out to obtain silica gel with microchannels; cut the silica gel into a fixed size and thickness, keep the microchannel at the central position, and obtain a microchannel module;

[0044] b) Embedding fluid conduction fibers into the microchannels of the module obtained in step a) to obtain a conduction module with microfluid conduction; cutting out holes in the wound contact dressing, and embedding the conduction modules into the holes to obtain Wound contact dressing with fluid conduction function; the pH response module is fixed on the transparent dressing patch, and then covered with the wound contact dressing with fluid conduction function to obtain an intelligent dressing.

[0045] In the invent...

Embodiment 1

[0055] (1) Weigh 10g of liquid silica gel A and B components with Shore A hardness of 15HA, mix and stir evenly, place in a vacuum drying oven for degassing at negative pressure -0.1Mpa for 5min, and inject the degassed silica gel solution into the channel The number is 5, and the channel diameter is 1 mm in the forming mold, placed in an oven at a temperature of 80 ° C, and taken out after a curing time of 1.8 hours to obtain silica gel with micro channels.

[0056] (2) Cut the silica gel with microchannels obtained in step (1) to a cross-sectional area of ​​4mm*4mm and a thickness of 2mm to obtain a microchannel module.

[0057] (3) Embedding four multi-strand cotton fibers with a diameter of 200 μm into the channel of the microchannel module obtained in step (2), cutting the fibers to have the same length as the channel, and obtaining a conduction module with microfluidic conduction.

[0058] (4) Cut out a hole with a size of 3mm*3mm on the alginate dressing (wound contact ...

Embodiment 2

[0063] (1) Weigh 10g of liquid silica gel A and B components with Shore A hardness of 35HA, mix and stir evenly, place in a vacuum drying oven for degassing at negative pressure -0.1Mpa for 3min, and inject the degassed silica gel solution into the channel The number is 1, and the channel diameter is 1 mm in a forming mold, placed in an oven at a temperature of 80 ° C, and taken out after a curing time of 1.8 hours to obtain silica gel with micro channels.

[0064] (2) Cut the silica gel with microchannels obtained in step (1) to a cross-sectional area of ​​4mm*4mm and a thickness of 2mm to obtain a microchannel module.

[0065] (3) Embedding four multi-strand cotton fibers with a diameter of 200 μm into the channel of the microchannel module obtained in step (2), cutting the fibers to have the same length as the channel, and obtaining a conduction module with microfluidic conduction.

[0066] (4) Cut out a hole with a size of 3mm*3mm on the alginate dressing (wound contact dr...

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Abstract

The invention provides a microfluid self-conduction wound monitoring type intelligent dressing and a preparation method thereof.The microfluid self-conduction wound monitoring type intelligent dressing comprises a transparent dressing patch, a pH sensor unit and a wound contact dressing, the pH sensor unit is composed of a pH response module, a micro-channel module and fluid conduction fibers, the fluid conduction fibers are embedded in a micro-channel of the micro-channel module, and the wound contact dressing is arranged in the micro-channel module; and the pH sensor is compounded with the pH response module to form a pH sensor unit capable of realizing fluid self-conduction. Compared with the prior art, the intelligent dressing provided by the invention realizes the continuous response of the pH signal through the self-transmission of the fluid in the micro-channel of the pH sensor unit, improves the sensitivity of the monitoring response, can avoid the influence of dressing environmental factors, can accurately monitor the pH change of a wound in real time on the basis of meeting the wound nursing requirement, and has a good application prospect. The infection information of the wound is fed back, rapid and instant treatment can be adopted, and therefore serious infection of the wound is avoided, and the wound dressing has a good application prospect in the aspect of wound dressings.

Description

technical field [0001] The invention relates to the technical field of dressings, in particular to a microfluid self-conducting wound monitoring smart dressing and a preparation method thereof. Background technique [0002] In daily life, people often encounter various injuries, which are caused by physical, chemical, thermal, mechanical, pressure, infection, disease and other factors, resulting in skin defects. Therefore, wound healing technology has great commercial market value, especially for chronic wounds. The needs of the field are more obvious. Dressing is an important part of the wound treatment process, not only can protect the wound from external infection, but also can promote wound cell proliferation. Despite great advances in wound dressing technology, a key deficiency of conventional dressings is their inability to provide immediate wound-related information about changes in the wound microenvironment including pH, temperature, bacterial load, tissue oxygen c...

Claims

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Application Information

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IPC IPC(8): A61F13/00A61F13/02
CPCA61F13/00051A61F13/00068A61F13/0216A61F13/0289A61F2013/00429A61F2013/00948A61F2013/0296
Inventor 程杰李嘉嘉崔景强李丹杰孟洁韦倩倩李艳群王幸幸程静静翟胜娜张洪亮
Owner 河南驼人医疗器械研究院有限公司
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