Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Intelligent dressing and preparation method thereof

An intelligent and dye technology, applied in dressings, viscous dressings, medical science and other directions, can solve the problems of accelerated wound infection and adverse wound recovery, and achieve the effect of avoiding serious infection and good application prospects.

Active Publication Date: 2020-04-07
河南驼人医疗器械研究院有限公司
View PDF10 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If such a high pH condition cannot be diagnosed and treated in time, it will accelerate the infection of the wound and is not conducive to the recovery of the wound.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Intelligent dressing and preparation method thereof
  • Intelligent dressing and preparation method thereof
  • Intelligent dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0044] The present invention also provides a preparation method of the smart dressing described in the above technical solution, comprising the following steps:

[0045] a) After mixing the alginate solution and the polyethylene oxide solution, sequentially add a dispersant and a dye-loaded silicon dioxide nanoparticle solution, stir evenly and let it stand for defoaming to obtain a spinning solution; Electrospinning to obtain an alginate spinning membrane; then place the alginate spinning membrane in a calcium chloride solution for cross-linking, then wash and dry to obtain an alginate / polyoxyethylene composite fiber membrane , to form a pH sensor unit after tailoring;

[0046] b) fixing the pH sensor unit obtained in step a) on a transparent dressing patch, and then covering the wound with a contact dressing to obtain a smart dressing.

[0047] In the invention, after mixing the alginate solution and the polyethylene oxide solution, the dispersant and the dye-loaded silicon...

Embodiment 1

[0059] (1) Stir and dissolve 4g alginate in 96mL deionized water to obtain alginate solution; stir and dissolve 4g polyethylene oxide in 96mL deionized water to obtain polyethylene oxide solution; then mix 40g alginate solution and 60g The polyethylene oxide solution was mixed and stirred, then 0.5 mL of glycerin and 5 mL of DMSO were added, and then 0.4286 g of a dye-loaded silica nanoparticle solution with a mass concentration of 7% was added, stirred evenly and left to stand for defoaming for 20 hours to obtain a spinning solution.

[0060] (2) Use electrospinning equipment to carry out electrospinning to the spinning solution obtained in step (1), adjust the positive voltage of the electrospinning machine to be 18kV, the negative voltage to be -5kV, the receiving distance to be 12cm, and the liquid output speed to be 1.2mL / h, to obtain alginate spinning membrane.

[0061] (3) placing the alginate spun membrane obtained in step (2) in a calcium chloride solution with a ma...

Embodiment 2

[0066] (1) Stir and dissolve 4g alginate in 96mL deionized water to obtain alginate solution; stir and dissolve 4g polyethylene oxide in 96mL deionized water to obtain polyethylene oxide solution; then mix 50g alginate solution and 50g The polyethylene oxide solution was mixed and stirred, then 0.5 mL of glycerin and 5 mL of DMSO were added, and then 0.4286 g of a dye-loaded silica nanoparticle solution with a mass concentration of 7% was added, stirred evenly and left to stand for defoaming for 20 hours to obtain a spinning solution.

[0067] (2) Use electrospinning equipment to carry out electrospinning to the spinning solution obtained in step (1), adjust the positive voltage of the electrospinning machine to be 18kV, the negative voltage to be -5kV, the receiving distance to be 12cm, and the liquid output speed to be 1.2mL / h, to obtain alginate spinning membrane.

[0068](3) placing the alginate spun membrane obtained in step (2) in a calcium chloride solution with a mas...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
pore sizeaaaaaaaaaa
Login to View More

Abstract

The invention provides an intelligent dressing. The intelligent dressing comprises a transparent dressing patch, a pH sensor unit which is fixed on the transparent dressing patch, and a wound contactdressing which covers the pH sensor unit. The pH sensor unit is formed by blending dye-loaded silicon dioxide nanoparticles with alginate and polyoxyethylene and then carrying out electrostatic spinning. Compared with the prior art, the intelligent dressing provided by the invention has the advantages that nanometer encapsulation of a dye is realized through the silicon dioxide nanoparticles loaded with the dye; the pH sensor unit is obtained; on the basis that the wound nursing requirement is met, the pH change of a wound can be monitored in real time; infection information of the wound can be fed back; rapid and timely treatment can be easily adopted; serious infection of the wound is avoided; and good application prospects are achieved in the aspect of wound dressing.

Description

technical field [0001] The invention relates to the technical field of dressings, and more specifically relates to an intelligent dressing and a preparation method thereof. Background technique [0002] In daily life, people often encounter various injuries, which are caused by physical, chemical, thermal, mechanical, pressure, infection, disease and other factors, resulting in skin defects. A key defect of traditional dressings is that they cannot provide instant wound-related information. Changes in the wound microenvironment include pH, temperature, bacterial load, tissue oxygen content, and inflammation levels. Therefore, the new generation of wound dressings can no longer be limited to simple protection, hemostasis or absorption of wound exudate, but should be a type of intelligent dressing that integrates multiple functions, which can instantly feed back important information inside the wound, so that Speed ​​up the wound care decision-making process and reduce freque...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61F13/02A61F13/00A61L15/18A61L15/26A61L15/28A61L15/42
CPCA61F13/02A61F13/00059A61F13/0276A61L15/26A61L15/42A61L15/18A61L15/28
Inventor 程杰崔景强王国锋李艳群王幸幸李嘉嘉桂鑫程静静田静翟胜娜夏怡琳李丹杰
Owner 河南驼人医疗器械研究院有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com