Application of Naoxintong preparation in preparation of medicine for treating non-alcoholic fatty liver disease
A non-alcoholic, brain-heart-passing technology, used in drug combinations, pharmaceutical formulations, plant raw materials, etc., can solve problems such as clinical application limitations, the impact of patients' quality of life and life expectancy, liver and kidney damage, etc., to expand the scope of medicinal use , the effect of improving liver function indicators
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Embodiment 1
[0024] Embodiment 1 in vivo animal model experiment
[0025] 1. Experimental materials
[0026] 1.1 Test drug: Naoxintong Capsules (NXT)
[0027] 1.2 Control drug: atorvastatin (ATO)
[0028] 1.3 High-fat feed: containing 21% fat and 1.5% cholesterol
[0029] 2. Experimental animals
[0030] APOE - / - 45 mice, SPF grade, male, weighing 20-25g, 15 C57BL / 6J mice, SPF grade, male, weighing 20-25g, experimental animal quality certificate number: SCXK (Guangdong) 2018-0002 issued by Guangdong Province Provided by the Animal Center for Medical Experiments.
[0031] 3. Experimental method
[0032] The present invention adopts APOE - / - The non-alcoholic fatty liver animal model was established by feeding mice with high-fat diet for 24 weeks, and its curative effect was verified by intragastric administration of Naoxintong capsules.
[0033] High-fat diet-induced fatty liver is recognized as one of the classic models of NAFLD, and rodents fed a high-fat diet for a long time will...
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