Characteristic substance concentration extraction separation device for regulatory analysis of finished drug products in the market
A separation device and feature technology, which are applied in the field of feature concentration, extraction and separation devices, can solve the problems that the degree of grinding cannot be guaranteed, the accuracy cannot be guaranteed, and the features are completely extracted, and the invention is conducive to rapid dissolution. , reduce the impact, avoid the effect of partial sublimation
Active Publication Date: 2022-05-31
广东预防医学健康研究院(有限合伙)
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Problems solved by technology
However, the conventional iodine content detection is mostly carried out by semi-manual and semi-mechanical methods, and the accuracy of this detection method is often not guaranteed.
Most of the traditional concentration, extraction and separation equipment do not have a device for crushing tablets, and some devices with a crushing function cannot guarantee the degree of crushing, and often the drug powder remains in the crushing device
On the other hand, most of the traditional extraction devices rely on shaking and vibration to help the contact between the extractant and the solvent. This extraction method often cannot completely extract the characteristic substances. Some equipment will use rapid stirring to assist the extraction, but the elemental iodine Due to its easy sublimation physical characteristics, elemental iodine is often lost due to local overheating in the process of rapid stirring
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[0027] As shown in FIG. 4, the crushing block component 13 includes a connecting frame 131, a displacement block 132, a first U-shaped cavity 133, and a second U-shaped
[0028] As shown in FIG. 4 , the upper cover 14 is provided with an air flow hole 141, and an air flow cavity is installed above the upper cover 14
[0029] As shown in Figure 2, the discharge part 15 includes a discharge plate 151, a vibration motor 152, and a discharge hole 153. The discharge plate 151
[0035] The above are only preferred embodiments of the present invention, and are not intended to limit the present invention.
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The invention discloses a characteristic substance concentration, extraction and separation device for regulatory analysis of finished drug products in the market, which includes a crushing component, a dissolution and extraction component, a concentration and separation component, and an outer frame. The components are installed on the second-layer partition, the concentration and separation component is installed on the inner bottom side of the outer frame, the dissolution and extraction component is located directly below the crushing component, and the concentration and separation component is located directly below the dissolution and extraction component. The crushing assembly of the present invention will cause the mutual impact between large and small drug fragments through the annular airflow, further crushing the tablet into smaller particles, and the dissolving and extracting assembly is driven by the injection force of carbon tetrachloride to rotate, which increases the The dissolution rate of the drug particles also enables the carbon tetrachloride solution to fully contact with the aqueous solution to avoid insufficient extraction.
Description
Feature Concentration Extraction Separation Device for Regulatory Analysis of Market Drug Products technical field The present invention relates to the technical field of extraction and separation of medicines, be specially the characteristic substance that is used for the supervision and analysis of finished drug products in the market Concentration extraction separation device. Background technique Medicine is an indispensable item in people's life, it is related to our life, health and safety, and directly affects the our quality of life. Many drugs containing molecular iodine are used for sterilization and anti-infection, and the concentration of available iodine is directly related to Drugs have the effect of bactericidal and anti-infective, and excessive iodine intake may lead to excessive thyroid hyperplasia, so the characteristics of The determination of molecular iodine content is the top priority of the supervision of iodine-containing drugs. However, the...
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IPC IPC(8): B01D11/02
CPCY02W30/62
Inventor 石小莉詹剑锋
Owner 广东预防医学健康研究院(有限合伙)