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Method and equipment for preparing linezolid

A technology of linezolid and equipment, applied in the field of compound synthesis, can solve the problem of lack of preparation quality detection and the like, and achieve the effects of convenient medicine taking, improved purity and improved efficiency

Inactive Publication Date: 2022-05-17
程竹隐
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] Therefore, the present invention provides a method and equipment for preparing linezolid to overcome the problem in the prior art that only time is used to control the preparation process and the preparation quality is not tested

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  • Method and equipment for preparing linezolid
  • Method and equipment for preparing linezolid
  • Method and equipment for preparing linezolid

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Embodiment Construction

[0061] In order to make the objects and advantages of the present invention clearer, the present invention will be further described below in conjunction with the examples; it should be understood that the specific examples described here are only for explaining the present invention, and are not intended to limit the present invention.

[0062] Preferred embodiments of the present invention are described below with reference to the accompanying drawings. Those skilled in the art should understand that these embodiments are only used to explain the technical principle of the present invention, and are not intended to limit the protection scope of the present invention.

[0063] It should be noted that, in the description of the present invention, terms such as "upper", "lower", "left", "right", "inner", "outer" and other indicated directions or positional relationships are based on the terms shown in the accompanying drawings. The direction or positional relationship shown is ...

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Abstract

The invention relates to the technical field of compound synthesis, in particular to a method and equipment for preparing linezolid, comprising: a preparation unit comprising a preparation module, a suction filtration module and a tabletting module, a detection unit arranged in a corresponding part in the preparation unit, and a central control unit respectively connected with the corresponding parts in the preparation unit and the detection unit. The method has the beneficial effects that whether a single preparation step in the preparation process is completed or not is judged through the detected data, the next preparation step is controlled when it is judged that the single preparation step is completed, and working parameters of components in equipment are adjusted in real time when it is judged that the single preparation step is not completed; the reaction process does not depend on the control of time, side reactions caused by incomplete reaction or overlong reaction time are reduced, the purity of the final product linezolid is further improved, and the preparation process tends to be intelligent, so that the method is more suitable for industrial production.

Description

technical field [0001] The invention relates to the technical field of compound synthesis, in particular to a method and equipment for preparing linezolid. Background technique [0002] Linezolid is a synthetic oxazolidinone antibacterial drug. It has good antibacterial activity against most Gram-positive pathogenic bacteria and has no cross-resistance with other antibacterial drugs. In addition, it is widely distributed in tissues and body fluids. And the convenient administration method makes it effective and safe in treating multidrug-resistant Gram-positive bacterial infections, and has received extensive attention in clinical practice. Linezolid has a unique antibacterial spectrum and antibacterial activity, coupled with its good tissue and body fluid distribution characteristics, so that its clinical status is quite important. [0003] Chinese Invention Patent Publication No. CN102321040B discloses a method for preparing a linezolid intermediate and a linezolid interm...

Claims

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Application Information

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IPC IPC(8): B01J19/18B01J4/00B01D29/03B01D11/04A61J3/10B30B11/04C07D263/20
CPCB01J19/18B01J19/0053B01J19/0066B01J19/0006B01J19/0013B01J4/001B01D29/035B01D11/04C07D263/20A61J3/10B30B11/04Y02A50/30
Inventor 程竹隐
Owner 程竹隐