Device for culturing pancreas islet cells in pancreas islet transplantation

Abstract

The invention provides a device for culturing pancreas islet cells in pancreas islet transplantation, and relates to the field of pancreas islet transplantation. The pancreas islet cell culture device in pancreas islet transplantation comprises a base, a connecting frame is in sliding connection with a side frame, and a pressing and discharging assembly is arranged between a rack rod and a box body. According to the pancreas islet cell culture device in pancreas islet transplantation, the output end of the motor drives the output shaft to rotate, the rotating plate rotates by 90 degrees at the opening in the middle of the partition plate, the traction rope drives the piston disc to slide between the partition plate and the box wall of the box body at the same time, and then air can be automatically supplemented into the box body at regular time; therefore, the oxygen content in the box body can be kept in a proper state in a closed temperature control state; temperature is sensed through the dispersing fins and conveyed into the strip-shaped cavity through the temperature guide strip, the strip built-in sliding piece drives the slender rod to slide relative to the vertical cavity, the contact piece at the top end of the slender rod slides to abut against the long contact strip, and then the refrigerating strip piece works to refrigerate and adjust the environment temperature in the box body.

Description

technical field [0001] The invention relates to the field of islet transplantation, in particular to a device for culturing islet cells in islet transplantation. Background technique [0002] Pancreatic islet transplantation has greatly promoted the research on diabetes treatment. It has important therapeutic value for insulin-dependent diabetes mellitus and diabetes with end-stage renal disease, so that patients are no longer dependent on exogenous insulin, reducing or delaying the occurrence and development of complications. Greatly improve patient quality of life and clinical outcomes. However, there are many difficulties in islet transplantation, which restrict its wide clinical application. The islet cell culture in islet transplantation generally uses a islet cell culture device. [0003] Most of the existing devices for islet cell culture in islet transplantation have the same structure. Since the suitable culture conditions for islet cells require the temperature o...

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Problems solved by technology

[0003] Most of the existing devices for islet cell culture in islet transplantation have the same structure. Since the suitable culture conditions for islet cells require the temperature of the culture environment, it is necessary to ensure that the temperature of the islet cells is in a stable and suitable state at all times, and the staff always Monitoring and adjusting the temperature inside the culture device greatly increases the workload of culture; and during the culture of islet cells, in order to make the temperature suitable for cell culture at all times, it is necessary to ensure that the culture device is in a closed state to avoid the external temperature from affecting the temperature inside the culture device. It will cause certain impact fluctuations, and the oxygen content in the air inside the airtight device will gradually decrease, which will affect the cell culture to a certain extent.

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