Method and system for constructing human body whole respiratory tract model conforming to real anatomical structure

Abstract

The invention discloses a method and system for constructing a human body whole respiratory tract model conforming to a real anatomical structure, and the method comprises the steps: obtaining the CT (Computed Tomography) tomographic image data of the upper part of a target object, carrying out the threshold segmentation, obtaining a respiratory tract mask, and carrying out the three-dimensional reconstruction, thereby obtaining a real respiratory tract model; generating a bronchial tree center line skeleton by using a Weibel model and using a three-dimensional rotation matrix with a random angle, and subdividing modeling to construct an ideal bronchial tree model conforming to an anatomical structure; generating a random point cloud according to the size of the pulmonary alveolus, generating a three-dimensional Thiessen polygon by using the random point cloud, and constructing a pulmonary alveolus path in the three-dimensional Thiessen polygon by using a myxomycete growth algorithm to obtain a respiratory tract end idealized polyhedral pulmonary alveolus model; and splicing and assembling the real respiratory tract model, the idealized bronchial tree model and the idealized polyhedral alveolar model at the tail end of the respiratory tract according to the anatomical structure to obtain a human body whole respiratory tract model. The model construction method provided by the invention is short in modeling period, high in reusability and good in expandability.

Description

technical field [0001] The invention relates to the field of biomedical engineering, in particular to a method and system for constructing a human whole respiratory tract model conforming to a real anatomical structure. Background technique [0002] New coronavirus pneumonia (Corona Virus Disease 2019, COVID-19), refers to the pneumonia caused by the 2019 new coronavirus infection, is an acute respiratory infectious disease. The new coronavirus can be transmitted directly through sneezing, coughing, droplets, etc. Inhalation of aerosols mixed with droplets in the air can also lead to infection, and it may also spread to the mouth, nose and eyes through the hands of the contaminated surfaces. mucous membranes cause infection. The continuous spread and mutation of viruses pose new challenges to vaccine development and improvement. Inhalation of aerosolized drugs is currently the preferred way to treat respiratory diseases, and inhaled vaccines are also expected to become an ...

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Problems solved by technology

[0006] In view of the above-mentioned deficiencies in the prior art, the purpose of the present invention is to provide a method and system for constructing a human body full airway model conforming to the real anatomical structure, aiming at solving the problem that the existing airway modeling method cannot obtain the geometry of bronchi at all levels in the whole airway, and cannot Reflects the real anatomical structure of the respiratory tract and the problem of long modeling cycle and low reusability

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