The invention belongs to the technical field of road engineering materials, and concretely relates to a method for preparing a hexagonal slope protection block by regenerating asphalt pavement surfacemilling materials. The prefabricated hexagonal slope protection block is prepared from, by weight, 18-22 parts of an RAP material (0-5 mm), 12-14 parts of an RAP material (5-10 mm), 7-9 parts of an RAP material (10-20 mm), 0.2-0.25 part of a regenerant, 1-2 parts of a fiber reinforcing agent, 1.6-2 parts of a stabilizer, 0.6-0.8 part of new asphalt, 2-4 parts of gum powder, 3-5 parts of an anticorrosive agent, 1.4-1.6 parts of a water and oil resistant agent, 0.8-1.2 part of rosin and 1-3 parts of an inorganic nano-ceramic heat insulation coating. The prefabricated hexagonal slope protectionblock prepared by crushing, screening, rebuilding, prefabricating and curing the waste milling material has the advantages of high compactness, high strength, durableness, long service life, and strong ability to resist oxidation, low temperature crack and erosion (salt erosion).