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Compound macrostem onion preparation for treating chronic obstructive pulmonary disease and its preparing method

A chronic obstructive and scallion technology, which is applied to medical preparations containing active ingredients, pharmaceutical formulas, respiratory diseases, etc., can solve problems such as unsatisfactory, and achieve the effects of taking convenience, improving pulmonary ventilation function, and reducing pulmonary arterial pressure

Inactive Publication Date: 2004-12-29
南京中医药大学附属医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, phlegm-heat syndrome is the most common clinical research on the TCM "syndrome" of COPD, but the current TCM treatment is not ideal in terms of cough and phlegm, spasm and asthma, antibacterial and anti-inflammatory effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1: the preparation of compound Xiebai dripping pills

[0024] Xiebai 9g Gualoupi 9g Jiang Pinellia 6g Coptidis 3g Citrus aurantium 9g, crush the above five herbs into a coarse powder (60 mesh), add 90% ethanol to extract 3 times, each time for 1 hour, each time add 160ml of 90% ethanol, combine ethanol The extract is filtered, the ethanol is recovered from the filtrate under reduced pressure, and concentrated properly to obtain a concentrated solution; the concentrated solution is vacuum-dried at 40-80°C to obtain a dry extract, which is crushed into a fine powder and added with molten PEG 6000 (Dry extract fine powder: PEG 6000 =3:7-9), mix well, seal and keep warm at 50-90°C, drop into methyl silicone oil (5-18)°C, remove the cooling liquid, and obtain.

Embodiment 2

[0025] Embodiment 2: the preparation of compound scallion tablet

[0026] Citrus aurantium 10g Guizhi 5g Ginseng 5g Atractylodes Rhizoma Atractylodes Rhizome 9g Xiebai 11g Gualoupi 11g Ginger Pinellia 8g Licorice 3g, crush the above eight herbs into coarse powder (20 mesh), add 90% ethanol to extract twice, each time for 1.5 hours, add each time Combine 400ml of 90% ethanol, combine the ethanol extracts, filter, recover the ethanol from the filtrate under reduced pressure at 40-80°C, and concentrate properly to obtain a concentrated solution; add an appropriate amount of dextrin to the concentrated solution, and vacuum-dry at 40-80°C to obtain a dry extract , crush the dry extract into granules, add magnesium stearate, mix well, and press into tablets to obtain.

Embodiment 3

[0027] Embodiment 3: Preparation of Compound Xiebai Capsules

[0028] Xiebai 10g Gualoupi 8g Jiang Pinellia 7g Coptidis 4g Citrus aurantium 7g, the above five ingredients are crushed into coarse powder (40 mesh), add 60% ethanol to extract twice, each time for 1 hour, each time add 60% ethanol 170ml, combined ethanol extraction liquid, filtered, the filtrate was recovered ethanol under reduced pressure at 40-80°C, and concentrated properly to obtain a concentrated solution; the concentrated solution was added with an appropriate amount of dextrin, and dried in a vacuum at 40-80°C to obtain a dry extract, which was crushed and packed Serve in capsules.

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PUM

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Abstract

The compound Chinese onion preparation for treating chronic obstructive lung disease is prepared with Chinese onion, trichosanthes peel, Chinese goldthread, immature bitter orange, cassia twig and other chinese medicine materials. The preparation process includes crushing material, ethanol extraction, depression recovery of ethanol, concentration, adding supplementary material, vacuum drying to obtain dry extract, crushing, and further steps to prepare tablet, capsule, drip pills and micro pills. The compound Chinese onion preparation has obvious functions of relieving cough, eliminating phlegm and relieving asthma, and may be used to treat chronic obstructive lung disease effectively. It is ideal medicine for COPD in acute stage and COPD in prolonged stage and chronic stage.

Description

1. Technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a compound preparation for treating chronic obstructive pulmonary disease (COPD) prepared by using Chinese herbal medicines as raw materials and a preparation method. 2. Background technology [0002] Chronic obstructive pulmonary disease (COPD, COPD for short) is a group of chronic respiratory diseases characterized by airway obstruction and ventilation dysfunction. Includes conditions such as chronic bronchitis and emphysema. Pulmonary heart disease is often complicated in the later stage, seriously endangering people's health, and its disability rate and mortality rate are very high, which has been generally paid attention to by the medical profession. In my country, chronic bronchitis accounts for about 3% of people over the age of 15, and 80% of pulmonary hypertension patients are caused by chronic bronchitis, which is one of the common refractory diseases. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P11/00
Inventor 奚肇庆居文政
Owner 南京中医药大学附属医院
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