Spray formulation of providone iodine

A technology of povidone-iodine and spray, which is applied in the direction of aerosol delivery, active ingredients of artificially synthesized polymer materials, digestive system, etc., and can solve problems such as lack

Inactive Publication Date: 2005-06-01
NANJING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is still a lack of formulations suitable for oral use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0104] Povidone Iodine 50g

[0105] Potassium iodate 1g

[0106] Potassium iodide 1.5g

[0107] Glycerin 200ml

[0108] Propylene Glycol 100ml

[0109] Tween-80 1g

[0110] Menthol 2g

[0111] water to 1000ml

[0112] The povidone-iodine was stirred and dissolved with 1 / 3 water to obtain solution I. Mix glycerol and / or propylene glycol and 1 / 3 of water to obtain solution II. The solution I and the solution II were combined and stirred to obtain the solution III. In addition, potassium iodide and potassium iodate were dissolved in a small amount of water, respectively, and then added, stirred until uniform, added Tween-80, menthol, and chocolate essence, and water was added to the total amount, and stirred evenly. Serve in a container with a spout.

Embodiment 2

[0114] Povidone Iodine 50g

[0115] Potassium iodate 1g

[0116] Glycerin 300ml

[0117] Tween-80 1g

[0118] Menthol 2g

[0119] Chocolate Flavor 10g

[0120] water to 1000ml

[0121] The preparation method is the same as in Example 1.

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Abstract

The invention discloses a povidone-iodine spray, which is characterized in that it contains active agents povidone-iodine, potassium iodate and / or potassium iodide, glycerin and / or propylene glycol, flavoring agents and water. It not only has stable quality, Moreover, it is non-irritating to the skin and sticky touch, and is suitable for oral use to prevent and treat bacterial, fungal and viral infections.

Description

1. Technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to a povidone-iodine-containing spray. 2. Technical background [0002] At present, the drug status of oral diseases and pharyngitis in my country is roughly as follows: Oral surgery (such as tooth extraction, dental correction, etc.) generally uses antibiotics to prevent wound infection, and the effect is good, but it is a systemic drug, not the most reasonable drug. Oral medicine, such as oral ulcers and other inflammatory treatments, mainly use topical anti-inflammatory drugs, but there is a lack of topical drugs with ideal curative effects. For all kinds of throat infections, oral anti-inflammatory and antibacterial drugs are the main treatment methods. [0003] Povidone-iodine is a soluble complex formed by iodine and polyvinylpyrrolidone (PVP). Compared with iodine, it has the advantages of good water solubility and low volatility. It is a broad-spectrum, high-...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/12A61K31/80A61P1/02A61P11/04
Inventor 马雪华
Owner NANJING UNIV
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