100 results about "Providone-Iodine" patented technology

The invention relates to a topically applied composition containing povidone iodine and mometasone furoate, in particular to a topically applied pharmaceutical composition which contains the micronized mometasone furoate, the povidone iodine and one or more physiologically acceptable excipients applicable to topical application; and in the pharmaceutical composition, the content of the povidone iodine is 1%-10%, and the content of the mometasone furoate is 0.01%-0.1%.

The invention provides a novel povidone-iodine antibacterial hydrocolloid dressing and a preparation method thereof. The preparation method comprises the following steps of: (a) adding styrene-isoprene segmented copolymer and mineral oil (medical-grade white oil) into an internal mixer at a temperature of between 120 and 170 DEG C, and softening for 5 to 10 minutes; (b) dosing tackifying resin and an antioxidant into the softened styrene-isoprene segmented copolymer, and mixing to obtain premix; (c) adding hydrocolloid particles, sodium carboxymethylcellulose and carboxymethyl chitosan into the premix; (d) uniformly spraying povidone-iodine into the mixture obtained in step (c) by using a povidone-iodine complex device; and (e) applying to a copolymer film or non-woven fabric, namely coating the hydrocolloid layer to a back-lining layer. The copolymer film or glassine paper is coated on the prepared hydrocolloid layer, which means that a release layer is coated on the hydrocolloid layer to obtain the povidone-iodine antibacterial hydrocolloid dressing. The povidone-iodine antibacterial hydrocolloid dressing has the advantages of reducing the side effect of antibiosis and improving the effect of constant antibiosis.

The invention relates to a film-forming agent capable of preventing cow mastitis, comprising by weight, 0.6 o 1.2 parts of povidone iodine, 1 to 2 parts of tween 80, 0.2 to 0.6 part of glycerine, 8 to 12 parts of PVA (polyvinyl acetate), and 100 parts of distilled water. The invention further relates to a preparation method of the film-forming agent. The preparation method includes the steps of sterilizing with distilled water, temperature adjusting, adding of the povidone iodine, glycerine, tween 80 and PVA, pH adjusting and the like. The components and production process are further simplified, thus the film forming speed is high and breathability is good, the film-forming agent is nonirritating to skin mucosa. Especially, the film-forming agent and the preparation method thereof have the advantages such as high antibacterial activity, short film-forming time, easiness of eluting or stripping, agent stability, convenience of use and the like.

The invention discloses a partial external use composition containing povidone Iodine and cyclodextrin inclusion glucocorticoid, which comprises povidone Iodine and glucocorticoid which serve as active components, and one or more of auxiliary materials which are suitable for skin administration; and the partial external use composition containing povidone Iodine and cyclodextrin inclusion glucocorticoid is characterized in that the glucocorticoid is included by beta-cyclodextrin or derivatives of the beta-cyclodextrin, the content of the povidone Iodine in the partial external use composition is 1%-10%.

The invention discloses a safe broad-spectrum povidone-iodine preparation and a preparation method and application thereof. Each 1000g of the safe broad-spectrum povidone-iodine preparation is prepared from 10 to 15.5g of polyvinylpyrrolidone, 5.5 to 7.5g of refined iodine, 1.8 to 8.3g of potassium iodide, 0.01 to 3g of potassium iodate, 0.01 to 1.25g of a surfactant, 2 to 8g of a pH regulator andthe balance of water. A weight ratio of the polyvinylpyrrolidone to the effective iodine is (1.6-3.6): 1. The safe broad-spectrum povidone-iodine preparation with a proper dosage cannot cause poisoning and digestive tract injury after being orally taken, can be used for preventing and treating diseases of animals, reducing antibiotic abuse and improving human food safety, and is good in stability, not easy to decompose under the illumination condition and long in preservation time.

The invention relates to a disposable operating towel which is attached by Iodophor adhesive and used in surgeries and a preparation method thereof. The operating towel is formed by sequentially stacking medical release paper, release tapes, a medical Iodophor pressure sensitive adhesive layer, an operating towel pasting film and a plastic protecting film or no plastic protecting film. The preparation method includes the following steps: evenly blending Iodophor solution and pressure sensitive adhesive slime to prepare the medical Iodophor pressure sensitive adhesive; evenly coating the medical Iodophor pressure sensitive adhesive on the pasting surface of the medical release paper and covering the operating towel pasting film on the medical Iodophor pressure sensitive adhesive layer for rolling, and placing for 1-7 days; separating the medical release paper from the operating towel pasting film after transferring the medical Iodophor pressure sensitive adhesive layer, and arranging the release tapes at two sides of the medical release paper; rolling and pasting the medical release paper at the lower layer, the operating towel pasting film at the middle layer and the plastic protecting layer at the upper layer into a whole; and then, parting off, folding, packaging and sterilizing. By adding Iodophor in the medical pressure sensitive adhesive, the disposable operating towel of the invention has broad antimicrobial spectrum, quick disinfection and bacteria inhibiting effect.

The invention discloses a povidone-iodine solution with enhanced stability and a preparation method thereof. The povidone-iodine solution consists of povidone iodine, sodium dihydrogen phosphate, disodium hydrogen phosphate dodecahydrate, potassium iodate, lauryl sodium sulfate and purified water, and the concentrations of the raw materials are as follows: 5-20 g/L of povidone iodine, 1-10 g/L ofsodium dihydrogen phosphate, 0.5-2 g/L of disodium hydrogen phosphate dodecahydrate, 0.2-1.0 g/L of potassium iodate, and 1-10 g/L of lauryl sodium sulfate, and the pH of a sodium hydroxide solution is adjusted to 5.20-5.30. The sodium dihydrogen phosphate and the disodium hydrogen phosphate dodecahydrate are used as a pH value adjusting buffer pair, so that the acid-base balance of the solution can be maintained, and a buffer effect can be achieved. The potassium iodate and the lauryl sodium sulfate are used as pH stabilizers, the sodium hydroxide is used as a pH regulator, and the pH value of the povidone-iodine solution can be controlled within a specified range, so that the stability of the effective iodine content is ensured, and the bactericidal efficacy of the povidone-iodine solution is maintained.

The invention discloses a compound povidone iodine suppository and a preparation method and an application thereof. The compound povidone iodine suppository comprises the following components by weight: 3-7 parts of povidone iodine, 3-7 parts of rheum officinale powder, 5-15 parts of eucalyptus oil, 30-50 parts of polyethylene glycol 1000, and 30-50 parts of polyethylene glycol 4000. The preparation method of the compound suppository is a hot melting molding method, which comprises the following steps: melting polyethylene glycol 1000 and polyethylene glycol 4000 to form a matrix; orderly and uniformly dispersing povidone iodine, rheum officinale powder, and eucalyptus oil in the matrix, finally pouring the mixture into a metal mold, cooling and demolding. The compound povidone iodine suppository widens the application dosage form of povidone iodine in clinical veterinary medicine, has good treatment effect on sow endometritis, can reach the purposes of safety, high efficiency, stability, convenient administration, low administration frequency, no environment pollution, and the like, and has important significance on clinical medication and veterinary drug development.

The invention belongs to the field of bark regenerants, and particularly discloses a bark regenerant. The bark regenerant at least comprises one of a bark regenerant I, a bark regenerant II and a bark regenerant III, wherein the bark regenerant I is prepared from nicotinic acid, glycine, thiamine hydrochloride, pyridoxine hydrochloride, vitamin, naphthylacetic acid and indolebutyric acid; the bark regenerant II is prepared from vitamin C, amoxicillin sulbactam, a povidone iodine preparation, polyvinylpyrrolidone, naphthylacetic acid and indolebutyric acid; the bark regenerant III is prepared from inositol, nicotinic acid, glycine, thiamine hydrochloride, pyridoxine hydrochloride, vitamin C, potassium iodide, sodium sulfate, potassium nitrate, calcium nitrate tetrahydrate, magnesium sulfate heptahydrate, manganese sulfate tetrahydrate, zinc sulphate heptahydrate, sodium molybdate, copper sulfate pentahydrate, ferric sulfate, naphthylacetic acid and indolebutyric acid. The bark regenerant can effectively promote regeneration of new barks of peeled trees, is general and is extremely good in use effect in most tree species.

A povidone iodine toothpaste for preventing and treating dental plaque is prepared through dissolving carboxymethyl cellulose sodium in glycerin, dissolving sodium alginate in purified water, mixing them together, adding sorbitol, stirring to obtain solution A, adding sodium laurylsulfate and potassuim iodate to purified water, heating, adding povidone iodine and sodium saccharin, stirring, mixing it with solution A, adding SiO2, stirring to obtain mixture B, dissolving mint oil in alcohol, adding it to mixture B, and using the solution of sodium dihydrogen phosphate or bisodium hydrogen phosphate to regulate pH=5.5-6.5.

The invention provides a safe and efficient animal semen disinfector and a preparation method therefor, which are aimed to fill the blank of animal semen disinfectors in the market. The safe and efficient animal semen disinfector includes the following components in percentage by weight: 4.0 to 6.0 percent of povidone iodine, 0.5 to 1.0 percent of antimicrobial peptides, 0.2 to 0.3 percent of vitamins, 0.1 to 0.2 percent of ethylenediamine tetraacetic acid, and distilled water. A mixture of the povidone iodine and the antimicrobial peptides is used as the semen disinfector for semen purification and disinfection for economic animals. Tests prove that the animal semen disinfector can safely kill the five commonest and most harmful viruses in boar semen, i.e., classical swine fever virus (CSFV), porcine circovirus type 2 (PCV-2), pseudorabies virus (PRV), porcine reproductive and respiratory syndrome virus (PRRSV), and porcine parvovirus (PPV), as well as other most pathogenic microorganisms; meanwhile, the animal semen disinfector can prolong the sperm motility and the sperm preservation time to a certain extent, and is non-toxic and harmless to fertilized ovums and embryos.

The invention discloses a povidone iodine effervescent tablet with sterilization and disinfection effects, and a preparation method thereof, and belongs to the technical field of disinfection preparations. The povidone iodine effervescent tablet is prepared from, by weight, 5-15 parts of povidone iodine , 2-6 parts of fumaric acid, 2-6 parts of sodium bicarbonate, 5-15 parts of mannitol, 3-8 parts of povidone K30 and 60-70 parts of microcrystalline cellulose. The invention also discloses the preparation method of the povidone iodine effervescent tablet. The povidone iodine effervescent tablet can be used for sterilizing water and disinfecting environment, devices and water used for animal body skins. The povidone iodine effervescent tablet is a disinfection antiseptic, and has a killing effect on multiple bacteria, spores, viruses and fungi. The action mechanism of the povidone iodine effervescent tablet is that the povidone iodine effervescent table depolymerizes and releases contained iodine for acting a bactericidal effect after the povidone iodine effervescent tablet is in contact with wounds or infected parts. The povidone iodine effervescent tablet has small irritation to tissues, is suitable for treating skin and mucous membrane infection, is a high-efficiency and low-toxicity sterilization medicine, and has a good killing effect on bacteria, viruses and fungi.

The invention relates to a formula of hand-washing-free efficient disinfection gel, and belongs to the technical field of disinfection product preparation. The formula is characterized in that povidone iodine is used as a solute, and glycerol, n-propanol and ethanol are used as solvents. The povidone iodine can be dissolved in alcohols, and 1.0-20 ppm of free iodine can be released; the viscosityof the disinfection gel can be changed by adjusting the ratio of the glycerol, the n-propanol and the ethanol; the sorbitan fatty ester can emulsify the glycerol, so that the glycerol, the n-propanoland the ethanol are mutually soluble; the glycerol has a moisturizing effect, so that the killing and inhibiting action time of iodine on pathogenic microorganisms is prolonged; the ethanol volatilizes quickly and has a quick-drying effect; and triton-100 can penetrate through the surface of a cell membrane, so that free iodine enters parasitic cells of the virus to achieve the effect of killing the virus. The gel has the advantages of being convenient to use, free of hand washing and capable of effectively killing bacteria and viruses.

The invention belongs to the technical field of medical treatment and in particular relates to a liquid band-aid and a preparation method thereof. The liquid band-aid is prepared from the following raw materials in percentage by mass: 20-30% of ethanol, 15-25% of nitrocellulose, 10-20% of isopropanol, 5-10% of glycerinum, 5-10% of povidone-iodine, 2-5% of beewax, 1-5% of borneol, 1-3.5% of menthol, 1-2% of polyvinyl alcohol and 0.1-0.2% of a silver citrate solution. The liquid band-aid compounded by the silver citrate solution, povidone-iodine, beewax, borneol and the like is relatively smallin skill irritation and quick to form a film, and has the functions of stopping bleeding, protecting wounds, preventing bacteria and eliminating inflammation and promoting wound healing. By adding thesilver citrate solution into the liquid band-aid, skin is far way from pollution as a result of antibacterial performance of silver. Growth of bacteria is controlled, and daily dirt is eliminated, sothat the liquid band-aid is suitable for all skin and crowds of all ages, and is a brand new natural skin care raw material.

Efficient skin disinfection solution is prepared from the following raw materials in parts by weight: 6 to 8 parts of chitosan quaternary ammonium salt, 4 to 7 parts of povidone iodine, 6 to 12 parts of lonicera japonica, 5 to7 parts of lavender, 4 to 5 parts of sucrose palmitate, 2 to 4 parts of perfluorocarboxylic acid salt, 4 to 7 parts of surfactants, 2 to 4 parts of radix sophorae flavescentis, 3 to 5 parts of myosoton aquaticum, 3 to 4.5 parts of arisaema fargesii, 4 to 8 parts of myristic acid isopropyl ester, 3 to 5 parts of isopropyl alcohol, 10 to 14 parts of distilled water, and 4 to 8 parts of ethyl alcohol. The efficient skin disinfection solution has the beneficial effects that bacteria on the skin can be killed very well, no pungent smell exists and the comfortableness is relatively good.

The invention discloses an anti-infection improved iodine-loaded titanium alloy antibacterial implant and a preparation method, the improved iodine-loaded titanium alloy antibacterial implant comprises a titanium alloy material, a porous micro-nano structure is constructed on the surface of the titanium alloy material, and povidone iodine is deposited and attached on the surface of the porous micro-nano structure to form an antibacterial coating. The invention relates to a preparation method of an improved iodine-loaded titanium alloy antibacterial implant, which mainly applies an electrochemical method to perform iodine impregnation on the surface of a micro-arc oxidation titanium alloy, and comprises the following two steps: constructing a porous structure on the surface of the titanium alloy, and performing iodine impregnation improvement treatment and iodine loading. According to the method, an existing titanium alloy surface iodine loading process is improved, so that the material production process is more controllable, and surface antibacterial components are more stable. The process is simple, the reaction conditions are appropriate, the advantages of high efficiency and short production period are achieved, and the obtained titanium alloy implant is quite remarkable in antibacterial effect.

The invention relates to a drug which is specially used for treating digestive tract diseases which are caused by broiler chicken, piglet bacteria, virus and the like and repairing the mucomembranous of the digestive tracts of the broiler chicken and the piglets, in particular to a povidone-iodine oral liquid and a method for producing the same, wherein the povidone-iodine oral liquid consists ofthe following components in mass fraction: polyvinylpyrrolidone, iodine, glycerol, lactic acid, glucose, vitamin C and distilled water; and the povidone-iodine oral liquid is produced by the steps ofpreparing the polyvinylpyrrolidone-iodine mixed liquor, preparing the vitamin C-glycerol mixed liquor, mixing, stirring, adding the lactic acid, detecting and packing. The povidone-iodine oral liquidprovided in the invention can effectively kill and suppress the mass growth of spoilage organisms in the digestive systems of the broiler chicken and the piglets, so the functions of the digestive systems of the broiler chicken and the piglets are effectively improved, the weight gains of the broiler chicken and the piglets are accelerated, all the ingredients in the formula are medicines withouttoxicity and medicine residual or in food grades, and the povidone-iodine oral liquid cannot generate drug resistance after long-term use and pollute environment. The method for producing the povidone-iodine oral liquid is simple and easy to operate, and is convenient to popularize and apply.

The invention provides an anti-infection and anti-coagulation coating for a central venous catheter. The anti-infection and anti-coagulation coating comprises the following raw materials in parts by weight: 0.1-1% of polyvinylpyrrolidone, 0.2-2% of minocycline hydrochloride, 0.7-1% of a KH560 silane coupling agent, 2-3% of povidone iodine and 90-93% of medical disinfectant fluid. The preparation method of the anti-infection and anti-coagulation coating for the central venous catheter comprises the following steps: a central venous catheter antibacterial sterilization elimination procedure, povidone iodine liquid layer preparation work, anti-infection and anti-coagulation blood layer preparation work, anti-infection and anti-coagulation central venous catheter preparation and finished product obtaining. The anti-infection and anti-coagulation coating is cured to the surface of the central venous catheter at high temperature, dip-coating processing is conducted in a multiple dip-coatingmode, the smoothness of the central venous catheter can be improved, the friction coefficient of the central venous catheter is reduced, and convenience of medical use and operation is guaranteed; andthe process is simple, the used raw materials are easy to obtain, the medical effect is obvious, the antibacterial and anti-infection rate is high, medical accidents can be reduced, and the medical operation safety is guaranteed.

The invention provides an iodine-supported titanium alloy medical component containing a polycaprolactone (PCL)/povidone-iodine (PVP-I) surface layer and a production method of the iodine-supported titanium alloy medical component. An iodine containing coating is fixed to a titanium alloy by micro-arc oxidation reaction and surface iodine modification, and a high polymer composite structure is constructed on the structure, so that stable antibacterial performance is obtained; a material prepared by the technology has a more remarkable broad-spectrum antibacterial function, and the antibacterial effective component is iodine; besides, the defects that the iodine on the surface of the material is instable and prone to volatilization by constructing a PCL/PVP-I surface layer structure are overcome, and the stability of the antibacterial performance of the material is guaranteed; and besides, with gradual degradation of the surface layer structure, the iodine under the surface layer structure is gradually released, and the effective antibacterial duration of the material is also prolonged to a certain extent. The iodine-supported titanium alloy medical component can effectively reduceearly-stage infection and related complications in a surgery using a titanium alloy implant at present.

The invention relates to a perfusion agent for treating cow endometritis, and further relates to a preparation method for the perfusion agent. Components of each 100 L of the perfusion agent comprise: 5-10 kg of povidone iodine; 5-10 kg of borneol; 0.1-0.5 kg of a suspending agent, the balance of polyethylene glycol-400. The perfusion agent is prepared through the following method: (1) respectively weighing the povidone iodine, the borneol and the suspending agent, then uniformly mixing to obtain a mixture I for later use; (2) adding 40-60 L of the polyethylene glycol-400 to the mixture I while stirring; after uniformly stirring, placing the resulting mixture containing the polyethylene glycol-400 in a grinder to carry out grinding for twice until the drug emulsion fineness is 200 mum to obtain a mixture II; (3) further adding the polyethylene glycol-400 to the mixture II until the total volume is 100 L, uniformly stirring and packing. According to the present invention, the perfusionagent adopts the combination method of the traditional Chinese drug and the western medicine, provides a significant therapeutic effect for the cow endometritis; and the drug resistance is difficult to be generated and the perfusion agent is easy to be used.

The invention discloses an iodine-starch aerogel and its preparation method and application in the antibacterial field. The preparation method comprises the following steps: taking soluble starch andiodine as raw materials, mixing the soluble starch and iodine in a solution, and making the solution into aerogel to obtain the iodine-starch aerogel. Compared with the prior art, the invention innovatively uses soluble starch as an iodine carrier to prepare the iodine-starch aerogel. Compared with stability of the Lugol's iodine solution (a potassium iodide solution of iodine) and commercial povidone iodine, the stability of iodine loaded in the aerogel is significantly improved. In addition, the iodine-starch aerogel has excellent solubility and antibacterial properties, can be used as an antibacterial agent and iodine-containing food, and has a remarkable effect. Besides, the preparation method of the invention is simple, the raw materials are safe and easily available, and the cost islow.