41 results about "Providone-Iodine" patented technology

The invention discloses toothpaste which is pasty and comprises an abrasive, a humectant, a foaming agent, water, a bacteriostatic agent povidone iodine, 0.5 wt%-5 wt% of magnesium carbonate particles and 5 wt%-15 wt% of chitosan.The toothpaste has the advantages that cross-linking points are formed through electrostatic attraction between a positively charged chitosan acid solution and negatively charged povidone iodine and silicon dioxide particles; the preparation method comprises the following steps: preparing chitosan by virtue of a sol-gel method so as to realize gelation of the chitosan, uniformly dispersing silicon dioxide particles, povidone iodine and magnesium carbonate nanoparticles in the chitosan gel to obtain pasty toothpaste with good performance, the pasty toothpaste has relatively good stability, and the gel structure can also be used as a carrier to load and slowly release povidone iodine, so that the antibacterial action time of the povidone iodine is prolonged, and long-acting antibacterial protection is provided. The toothpaste disclosed by the invention has a good cleaning effect and antibacterial performance, is suitable for more user groups, especially crowds with sensitive oral cavities, and has important market requirements and application prospects.

The present invention relates to a single dose plastic container comprising between 0.2 and 3.0 ml of an aqueous pharmaceutical composition comprising from 0.50 to 1.20 % by weight of povidone-iodine and to its use in the treatment of conjunctivitis.

The present invention discloses a long-lasting intelligent composite antibacterial coating with dual pH response function and its preparation method, including: 1) constructing a nanotube structure on the surface of a pretreated titanium alloy substrate by a surface anodizing process; 2) combining a cyclic vacuum infusion + low-temperature micro-airflow process, infusing a povidone-iodine mixed solution into the nanotube pores on the titanium alloy surface; 3) after the titanium alloy surface is washed with water, a surface silanization treatment is performed to introduce a silane preparation with a double bond; 4) combining a surface cyclic light curing process, NAC-ChiMA is introduced into the substrate surface by a double bond addition reaction between the silane preparation and chitosan (NAC-ChiMA) modified with MA and NAC, to achieve the preparation of a composite antibacterial coating. The composite coating realizes the sequential release and slow release of NAC and povidone-iodine through the characteristics of vacuum drug loading and dual pH response, first destroying the extracellular polymeric substances of the bacterial biofilm, and then killing the bacteria in the biofilm, thereby achieving effective treatment of orthopedic implant infection.

Proposed is an incise drape including a base layer, and an adhesive layer formed on the base layer and containing acid-treated chitosan, povidone-iodine, and acrylate copolymer, wherein the adhesive layer contains less than 1 part by weight of povidone-iodine, and acid-treated chitosan in an amount of 1.5 to 5 parts by weight relative to povidone-iodine.

The utility model relates to a povidone iodine solution quantitative filling machine for aquatic products. Comprising a mounting bracket, a lifting driving device is mounted at the top of the mounting bracket, a lifting mounting seat is mounted on the lifting driving device, a plurality of groups of quantitative liquid taking devices are mounted on the lifting mounting seat, a three-way valve assembly is mounted at a lower port of each quantitative liquid taking device, and a filling head structure is mounted on each three-way valve assembly; the positioning liquid receiving device is mounted on the mounting bracket; the positioning liquid receiving device comprises a bottle clamping frame structure, two sets of mounting optical shafts are fixedly connected to the bottle clamping frame structure, a rear positioning assembly is slidably mounted between the two sets of mounting optical shafts in a sleeved mode, and the positioning liquid receiving device further comprises a rear positioning driving assembly used for driving the rear positioning assembly to move in the axial direction of the mounting optical shafts. The front positioning assembly and the liquid receiving groove are installed between the two sets of installation optical shafts in a sliding mode, and the front positioning driving assembly is used for driving the front positioning assembly and the liquid receiving groove to synchronously move in the axial direction of the installation optical shafts. According to the povidone iodine water solution quantitative filling device, povidone iodine water solution can be efficiently, accurately and quantitatively filled, residual liquid dripping from the filling head is automatically collected after the filling operation is completed, and the residual liquid is prevented from polluting a filling container and a production workshop.

The invention discloses toothpaste containing povidone iodine and modified activated carbon, the toothpaste comprises modified activated carbon, povidone iodine and an auxiliary agent, and the modified activated carbon is activated carbon with mesoporous silica particles grown in situ on the surface. According to the toothpaste, the active carbon raw material modified by silicon dioxide and the povidone iodine serving as a broad-spectrum bacteriostatic agent are stirred and mixed, so that the povidone iodine is uniformly distributed in pores of the active carbon and mesoporous silicon dioxide, and the stability of the povidone iodine in the toothpaste is improved; meanwhile, the activated carbon and the mesoporous silica are compounded in a specific mode, so that a better friction cleaning effect is achieved, and a stronger and more lasting antibacterial effect is achieved; the friction agent mesoporous silica is deposited on the surface of the active carbon in situ, the dispersion stability of the friction agent silica can be improved, the active carbon is matched with the silica, the cleaning effect can be enhanced, and the oral cavity problem can be effectively improved.

The application discloses a multifunctional antibacterial coating bone implant device based on a selective vacuum perfusion process and a preparation method thereof. The method comprises the following steps: 1) pretreating a titanium alloy base; 2) performing anodic oxidation treatment on the pretreated titanium alloy base to construct a nanotube structure on the surface of the titanium alloy base; 3) selectively coating the treated titanium alloy base with a hydrogel adhesive, then immersing the titanium alloy base in a povidone iodine mixed solution to perform vacuum perfusion, and performing post-treatment, then again performing selective coating, immersing the titanium alloy base in a solution containing a bone growth promoting factor to perform vacuum perfusion, and performing post-treatment, then again performing selective coating, immersing the titanium alloy base in a solution containing a blood vessel growth promoting factor to perform vacuum perfusion, and performing post-treatment; and 4) encapsulating the obtained sample surface with an in-situ self-polymerized polydopamine layer, washing and freeze-drying. The bone implant device has antibacterial, bone growth promoting and blood vessel growth promoting functions, and can greatly improve the curative effect on bone fracture symptoms accompanied by infection.

The invention relates to a disinfection product, in particular to a povidone iodine disinfection product. The povidone-iodine disinfectant is prepared from the following components in percentage by mass: 0.1 to 1 percent of povidone-iodine, 0.001 to 0.01 percent of PHB (Polyhydroxybutyrate) liposome nanoparticles, 0.03 to 0.1 percent of pH (Potential of Hydrogen) regulator, 0.5 to 1.5 percent of humectant and the balance of purified water, the preparation method of the disinfectant comprises the following steps: preparing a solution of the PHB liposome nanoparticles containing povidone iodine; weighing a solution of the povidone-iodine-containing PHB liposome nanoparticles according to a prescription amount, adding the solution into a preparation tank, adding a proper amount of purified water, and uniformly stirring and dissolving; weighing the pH regulator according to the prescription amount, adding the pH regulator into the preparation tank, and uniformly stirring; weighing the moisturizing agent according to the prescription amount, adding the moisturizing agent into the preparation tank, adding the rest purified water, stirring and dissolving uniformly, and filtering to obtain the disinfectant. The disinfectant does not need to be diluted before being used, can be directly used, is convenient to operate, has good stability and adhesiveness and is free of irritation; meanwhile, the preparation process is safe and simple.

The invention relates to the field of animal winter skin care, and discloses a dairy cow and sheep nipple anti-freezing medicated bath liquid which comprises the following components in parts by mass: 50-60 parts of deionized water, 15-18 parts of a softening agent, 10-12 parts of an emollient, 8-12 parts of a humectant, 10-15 parts of an anti-freezing agent, 5-7 parts of essential oil, 4-5 parts of a traditional Chinese medicine extract, 3-5 parts of an antioxidant liquid and 5 parts of an antibacterial agent. The antifreezing agent is one of acidic phosphate amine salt, alkylamine, fatty acid amide, organic acid ester or alkyl succinimide, the antioxidant liquid is one of hindered phenol antioxidant, phosphite ester antioxidant or sulfur-containing antioxidant, and the antibacterial agent is povidone iodine. By adding the softening agent, the emollient and the humectant, the protective bath lotion can extend into the skin to improve the moistening degree of the skin, and meanwhile, the traditional Chinese medicine extract is added, so that the protective bath lotion has a very good immune regulation function, improves the resistance of an organism, nourishes dry and rough skin and further improves the anti-freezing effect.

To provide a mouthwash mixed with povidone iodine (PVPI), containing PVPI in a higher concentration than a conventional product (7%), and to provide a method for producing the same.SOLUTION: A method for producing a povidone-iodine-containing mouthwash containing povidone iodine in an amount of 10% by mass or more based on the total amount (100% by mass) of the mouthwash, the method comprising the steps of: 2.14 4.28, A method for producing a gargle, comprising the steps of: dispersing PVPI in PG to obtain a dispersion; and mixing the dispersion with a mixed solution a1 in which at least one selected from the group consisting of ethanol, glycerin, D-sorbitol solution (70%), saccharin sodium, and 1-menthol is dissolved in water, or a mixed solution a1 in which potassium iodine is further dissolved in the mixed solution a2.SELECTED DRAWING: None

A ready-to-use, gamma-ray sterilized, surgical antiseptic composition comprising an initial non-toxic concentration of povidone-iodine above a minimum effective concentration of available iodine, iodide in sufficient quantity to provide donor iodine upon gamma irradiation to stabilize said povidone-iodine and maintain said minimum effective concentration of available iodine, and a buffered saline solution.

The invention discloses a composite antibacterial toothpaste, which comprises a friction agent, a humectant, a thickening agent, a foaming agent, a sweetening agent, water and a bacteriostatic agent, the bacteriostatic agent comprises nano silver particles and povidone iodine, and the friction agent comprises hydrated silica, medium particle size bamboo charcoal and small particle size bamboo charcoal according to a mass ratio of 8: 0.5: 1.5. The nano-silver particles are loaded in the medium-particle-size bamboo charcoal and the small-particle-size bamboo charcoal. The two bacteriostatic agents povidone iodine and nano-silver particles are combined for use, so that the growth of microorganisms can be inhibited through different mechanisms, the povidone iodine and the nano-silver particles cover different bacteria to form a synergistic effect, and lasting antibacterial protection is provided. In addition, the friction agent with specific composition can provide a better cleaning effect, reduces potential damage to teeth and gingiva, realizes a slow release effect of a bacteriostatic agent, has an excellent antibacterial effect and good safety, and can effectively solve the problem that the antibacterial effect is reduced due to the fact that silver ions react in an iodine solution to generate precipitates.

The present invention relates to kits, methods and systems for modulating free iodine in PVP-I, facilitating antimicrobial action while also ensuring compatibility with diagnostic assays.

A rapid evaluation method for the stability of a povidone-iodine solution relates to the technical field of detection methods, and comprises the following steps: S1, selecting a plurality of test attenuation rates of a povidone-iodine solution sample; s2, screening out samples with the attenuation rate equal to 8%, and calculating a chromatic aberration average value S1 of the samples; s3, the filter paper is placed on the clean glass surface, and the chromatic aberration average value S0 of the filter paper is calculated; s4, calculating a detection threshold value according to a formula delta1 = S1-S0 =-3; s5, calculating the average value S 'of the povidone-iodine product of which the stability is to be evaluated; S6, putting filter paper on a clean glass surface and calculating the average value S' 0 of the filter paper; s7, calculating the relative blank color difference value delta '= S'-S '0 of the sample to be detected; if delta 'is greater than-3, judging that the product is qualified; and-3, judging that the product is unqualified; and S8, judging the effectiveness of the detection in the steps S5-S7. According to the method, the stability of the povidone-iodine solution which is actually detected can be evaluated in a short time, the test period is shortened, the detection efficiency is improved, the detected data is verified through the prior art, and data support is provided for actual application.

The present application relates to the technical field of private part care bacteriostatic agent, and discloses a mild and stable povidone iodine private part bacteriostatic care liquid and a preparation method thereof.The care liquid comprises a copolymerized povidone VA64-iodine complex, a surfactant, a moisturizing agent, a conditioning agent, a thickening agent, a buffer, a preservative and water, the effective iodine content is 0.05-0.20 g / L, and the pH is 3.8-5.5.The present application improves the stability of effective iodine and reduces irritation through mechanical grinding complexing, low-temperature cold compounding and buffer adjustment, and is suitable for daily bacteriostatic care of private parts.

A method and system for sterilizing an iodine disinfectant solution are disclosed. The iodine disinfectant solution can contain crystalline iodine and / or povidone iodine (PVP-I). The method includes supplying the iodine disinfectant solution to a sealed container. During the sterilization cycle, the method further includes heating the iodine preservative solution within the sealed container to a sterilization temperature sufficient to produce free elemental iodine within the sealed container. The method further includes applying a positive pressure within the sealed container to pressurize the free elemental iodine to produce sterilized iodine within the sealed container.

The invention relates to the technical field of veterinary drugs, in particular to povidone-iodine oral liquid and a preparation method thereof. The oral liquid comprises the following components: povidone, a water-soluble anionic polysaccharide derivative, iodine, a metal ion chelating agent, a nonionic surfactant, a water-soluble organic solvent, a pH regulator, a flavoring agent and water. Compared with traditional prevention and treatment preparations with the problems of low bioavailability, poor stability, poor taste and the like, the povidone-iodine oral liquid can effectively prevent and treat the diseases, by optimizing the formula of povidone-iodine and the composite auxiliary materials, adding a proper taste regulator, improving the production process and simplifying the process, the cost is greatly reduced, and the oral liquid is suitable for large-scale popularization and application. The bioavailability is improved, the stability is enhanced, the palatability is improved, the production operation is simpler and more convenient, industrial production can be better adapted, and a practical solution is provided for the breeding industry.

Described herein are polymerizable compositions useful as surgical adhesives, where the compositions include at least one antimicrobial agent dissolved in a cyanoacrylate monomer, where the at least one antimicrobial agent includes a cinnamon derivative comprising at least one of cinnamaldehyde, a cinnamic ester, a cinnamon essential oil, and where the at least one antimicrobial agent optionally further includes triclosan or a derivative thereof and / or povidone iodine. The antimicrobial agent is soluble in and compatible with the cyanoacrylate monomer.

The present application relates to the technical field of veterinary disinfectant, and proposes a povidone iodine solution for chicken disinfection and a preparation method thereof.The povidone iodine solution for chicken disinfection is composed of the following components in mass percentage: 1-10% of povidone iodine, 0.1-0.5% of potassium iodate, 5-20% of polyvinylpyrrolidone, 1-5% of patchouli extract, 2-10% of emollient, 0.1-0.5% of pH buffer, and the balance of water.The above technical solution solves the problem of poor disinfection effect and stability of povidone iodine in the prior art.The povidone iodine solution prepared by the present application is mild and non-irritating, has long-lasting effect and is less likely to produce drug resistance, and is suitable for chicken disinfection.

The present invention relates to preparation of Povidone Iodine Ointment in combination with biopolymer Chitosan for synergistically enhancing the anti- septic / antibacterial activity of Povidone Iodine and espousing the wound healing effect of the biopolymer Disclosed herein is composition comprising of Povidone Iodine and a biopolymer in an ointment base, wherein the ointment base may comprise of a waxy material, a solvent, thickening agent, solubilizer, an acid, a buffering agent, and water as co-solvent. In certain aspects, the biopolymer is chitosan which is an unbranched binary polysaccharide consisting of two units N- acetyl-D-glucosamine and D-glucosamine. A method of making the ointment is also disclosed in the application. The key aspects of the invention are that the Povidone Iodine is added in an amount between 5 % (w / w) and 10% (w / w), and the chitosan has a molecular weight in the range of 50 kDa to 5000 kDa and added in an amount of 0.1% (w / w).

The invention relates to aqueous solutions containing a combination of lactoferrin with lactoperoxidase or with povidone iodine, encapsulated in liposomes, as active ingredients together with other components for use as nasal drops and nebulizers in combination with a mouth and face spray with antiviral, antiseptic and anti-inflammatory effects.

The invention discloses a treatment device and a treatment method for ichthyophthiriasis of largemouth bass, and belongs to the technical field of aquaculture. The device comprises a treatment bin, a filtering bin and a medicine bin, a disinfecting and killing device is further arranged between the filtering bin and the medicine bin, and all the components cooperate to achieve water circulation, temperature control, salinity adjustment, medicine mixing and disinfecting and filtering. During treatment, the temperature of a water body is stable, the salinity is accurately adjusted through the salt adding box, the salinity is adjusted from high salinity to low salinity, then melia azedarach oil and eucalyptus oil with specific dosage are matched to kill ichthyophthirius multifiliis, and then povidone iodine is used for disinfection and vitamin C is used for assisting recovery. The method solves the problems of large drug dosage, high energy consumption, inaccurate salinity adjustment and easy disease recurrence in the prior art, has the advantages of drug and energy consumption saving, accurate salinity adjustment, thorough treatment and simple and convenient operation, and is suitable for efficient treatment of industrial largemouth bass ichthyophthiriasis.

This invention discloses a compound oral rinse composition and its preparation method, relating to the field of oral rinse technology. The compound oral rinse composition comprises the following components: a complex active ingredient, a mucosal repair agent, an anti-inflammatory synergist, a moisturizer, a solubilizer, a flavoring agent, a pH adjuster, and water, with the sum of all components being 100 wt%. The complex active ingredient is povidone-iodine and tinidazole, and the mucosal repair agent is at least one selected from chitosan, zinc hyaluronic acid, and silk fibroin. This invention enhances therapeutic efficacy through the synergistic effect of the complex active ingredient and the mucosal repair agent, effectively improving the oral environment and achieving anti-inflammatory and mucosal repair effects.

This invention discloses a formulation process for a vaginal antibacterial solution that combines antibacterial, repair, and purification functions. It relates to the field of antibacterial wash manufacturing. By weight, its active ingredients consist of 5-15 parts povidone-iodine, 3-8 parts Sophora flavescens root extract, 2-6 parts Cnidium monnieri extract, 1-5 parts yeast extract, 2-8 parts aloe vera extract, 1-4 parts witch hazel extract, and purified water. This invention achieves a synergistic closed-loop effect of antibacterial, detoxifying, and repairing functions through specific component combinations and ratios. Povidone-iodine, combined with Sophora flavescens root extract and Cnidium monnieri extract, achieves dual-targeted antibacterial action; Sophora flavescens root extract and Cnidium monnieri extract, combined with witch hazel extract, achieve active detoxification through physical and chemical adsorption solidification; and aloe vera extract and yeast extract synergistically promote mucosal repair.

The invention discloses a compound oral gargle composition and a preparation method thereof, and relates to the technical field of oral gargle. The compound oral gargle composition comprises the following components: a compound active component, a mucous membrane repairing agent, an anti-inflammatory synergist, a humectant, a solubilizer, a flavoring agent, a pH regulator and water, the content sum of the components is 100 wt%, the compound active component is povidone iodine and tinidazole, and the mucous membrane repairing agent is at least one of chitosan, zinc hyaluronate and silk fibroin. Through the synergistic effect of the composite active ingredients and the mucous membrane repairing agent, the curative effect is improved, the oral environment can be effectively improved, and the effects of diminishing inflammation, repairing mucous membranes and the like are achieved.

The present invention provides a gel-forming ophthalmic composition comprising povidone iodine, a steroid, a polysaccharide polymer gelling agent, water, and suitable excipients for ophthalmic preparations. This composition is not only stable, but also can effectively kill a variety of pathogens, rapidly alleviate associated signs and symptoms, and treat ocular diseases.

A ready-to-use, gamma-ray sterilized, surgical antiseptic composition comprising an initial non-toxic concentration of povidone-iodine above a minimum effective concentration of available iodine, iodide in sufficient quantity to provide donor iodine upon gamma irradiation to stabilize said povidone-iodine and maintain said minimum effective concentration of available iodine, and a buffered saline solution.

The present application relates to the technical field of medicine, provide a kind of for eye surgery anesthesia and disinfection ophthalmic composition and its preparation method and application.The ophthalmic composition includes: disinfectant, local anesthetic, pH adjusting agent and water for injection, without preservative;The disinfectant is selected from povidone-iodine, and the local anesthetic is selected from one or more of tetracaine hydrochloride and oxybuprocaine hydrochloride.In the ophthalmic composition of the application, by povidone-iodine, tetracaine hydrochloride and oxybucaine hydrochloride concentration, pH control and stabilizer screening, the stability of the coexistence system is improved, and anesthesia and disinfection in ophthalmic clinical operation have important contribution.

The utility model provides a photocuring iodine-containing surgical membrane structure, which belongs to the technical field of photocuring iodine-containing surgical membranes and comprises a release base material layer, a use base material layer and an iodine-containing adhesive layer which are sequentially stacked. Wherein the iodine-containing adhesive layer is connected with the used base material layer and the release base material layer, the iodine-containing adhesive layer is formed by mixing povidone iodine and a photocuring UV acrylic acid hot melt adhesive, the iodine-containing adhesive layer is used for improving the antibacterial property and the photocuring characteristic of the photocuring iodine-containing surgical membrane, the used base material layer is a PE membrane or a polyurethane membrane, and the release base material layer is a polyurethane membrane. The release base material layer comprises glassine or white silicon, the release layer is used for transferring a mixed iodine-containing adhesive and protecting the iodine-containing adhesive layer, an antibacterial component in the iodine-containing adhesive layer is povidone iodine, and the problems that a traditional surgical membrane is high in sensitization, free of antibacterial performance and the like can be solved.