Feeze-dried powder injection contg. tatol saponin by refinement of American ginseng and leaves and stem of Americal ginseng, and its prodn. process

Abstract

A freeze dried common saponin injection of American ginseng or its stem and leaf is prepared through breaking, decocting, collecting decoction, concentrating, adding alcohol, filtering, recovering alcohol, regulating pH, laying aside, filtering, macroreticular resin adsorption, eluting, collecting eluting liquid, flowing through another two resin columns, recovering alcohol, concentrating, drying to obtain powder, dissolving in alcohol, decoloring, filtering, sterilizing and freeze drying. Its advantage is high purity up to 90% or more.

Description

Technical field: [0001] The invention discloses a freeze-dried powder injection of American ginseng and refined total saponins from American ginseng stems and leaves and a production process thereof, and relates to a new process for preparing freeze-dried powder injections of American ginseng and refined total saponins from American ginseng stems and leaves and American ginseng and refined total saponins from American ginseng stems and leaves, belonging to medicine formulation field. Background technique: [0002] American ginseng (panax quinguefolium Lima.) and American ginseng stems and leaves contain a variety of identical ginsenosides. Studies have shown that the total saponins of American ginseng stems and leaves have significant effects on experimental myocardial infarction and isoproterenol-induced myocardial ischemia in rats. Protective effect; it can increase the ability of the myocardium to tolerate hypoxia; it can obviously increase the blood flow of the animal my...

AI Technical Summary

Problems solved by technology

[0003] At present, because there is no high-efficiency filtration process in the production of American ginseng and total saponins from American ginseng stems and leaves, and no very effective method is used to precipitate impurities, there is no pH adjustment when recovering ethanol, and there is no further decolorization after passing through the resin column, so The total saponin content of the produced American ginseng and the total saponins of American ginseng stems and leaves is low, the total saponin content is only 50%-75%, and the amount of impurities contained is high; the previous preparation process still has the use of organic solvents in the extraction process, resulting in cost High, industrialized production is highly dangerous, not conducive to industrialized production