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Use of scutellarin in preparing medicine for treating or preventing stomatocace

A technology of oral ulcer and baicalin, which is applied in the field of application of baicalin in the preparation of drugs for the treatment or prevention of oral ulcer, and can solve the problems of no anti-inflammatory effect, insignificant bactericidal and anti-inflammatory effect, and insignificant anti-inflammatory effect

Inactive Publication Date: 2007-02-07
RENHE YIKANG MEDICINE TECH TIANJIN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Lysozyme has a certain bactericidal effect, but has no anti-inflammatory effect; watermelon cream has a good taste, but its bactericidal and anti-inflammatory effects are not obvious; Patients with hyperthyroidism and iodine allergy

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0025] Preparation Example 1: Preparation of Baicalin Buccal Tablets

[0026] Pass 50g of baicalin through a 100-mesh sieve (the same below), add 150g of maltodextrin, mix evenly, and sieve, add 200g of mannitol, mix evenly, and sieve, add 400g of powdered sugar, mix evenly, and sieve to obtain a mixed powder, and use 2 %PVP K30 120ml of 75% ethanol water solution is used as a binder, making suitable soft materials, granulated with 18 mesh sieve, oven dried at 60°C for 2 hours, granulated with 16 mesh nylon sieve, added with 8g of magnesium stearate, mixed evenly, oval special-shaped punched tablets Made into 1000 tablets, the tablet weight is about 800mg / tablet.

preparation example 2

[0027] Preparation Example 2: Preparation of Buccal Tablets

[0028] Pass 100g of baicalin through a 100-mesh sieve (the same below), add 150g of maltodextrin, mix evenly, and sieve, add 200g of mannitol, mix evenly, and sieve, add 350g of powdered sugar, mix evenly, and sieve to obtain a mixed powder, and use 2 %PVP K30 120ml of 75% ethanol water solution is used as a binder, making suitable soft materials, granulated with 18 mesh sieve, oven dried at 60°C for 2 hours, granulated with 16 mesh nylon sieve, added with 8g of magnesium stearate, mixed evenly, oval special-shaped punched tablets Made into 1000 tablets, the tablet weight is about 800mg / tablet.

preparation example 3

[0029] Preparation Example 3: Preparation of Baicalin Buccal Tablets

[0030] Pass 5 g of baicalin through a 100-mesh sieve (the same below), add 350 g of maltodextrin, mix evenly, and sieve, add 250 g of mannitol, mix evenly, and sieve, add 200 g of powdered sugar, mix evenly, and sieve to obtain a mixed powder, and use 2 %PVP K30 120ml of 75% ethanol aqueous solution is used as a binder, making suitable soft materials, granulated with 18 mesh sieve, oven dried at 60°C for 2 hours, granulated with 16 mesh nylon sieve, added with 9g of magnesium stearate, mixed evenly, oval special-shaped punched tablets Made into 1000 tablets, the tablet weight is about 800mg / tablet.

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PUM

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Abstract

The present invention relates to the application of baicalin in preparing medicine for preventing and treating somatocase, and is especially the application of baicalin buccal tablet, powder preparation and spray in preventing and treating somatocase. The present invention also provides the preparation process of baicalin buccal tablet, powder preparation and spray. The baicalin buccal tablet, powder preparation and spray have comprehensive effects of resisting bacteria, resisting inflammation, resisting allergy and resisting virus.

Description

technical field [0001] The present invention relates to the application of baicalin in preparing medicine for treating or preventing oral ulcer, and also relates to baicalin buccal tablet, powder or spray for treating or preventing oral ulcer. Background technique [0002] Scutellaria baicalensis is a traditional Chinese medicine for clearing away heat and detoxifying. It is bitter in taste and cold in nature. Modern studies have shown that the main active ingredient of Scutellaria baicalensis is baicalin (formerly known as baicalin), which has anti-oxidation, anti-inflammatory, anti-allergic, antibacterial, anti-viral and anti-tumor effects ("Research progress on chemical components of Scutellaria baicalensis and extraction methods of baicalin "Li Tongtong et al., "Tianjin Pharmacy", June 2002, the 7th page of the 3rd issue of the 14th volume). As a medicinal raw material, baicalin has been recorded in my country's drug standards, but currently it is mainly used clinically...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61K9/20A61K9/12A61K9/14A61P1/02
Inventor 李桂生李八方蒋王林傅风华王超云刘珂
Owner RENHE YIKANG MEDICINE TECH TIANJIN