Dynamic circulating-stage continuous countercurrent extraction process

Abstract

The dynamic circulation staged continuous countercurrent extraction process is characterized by that it has several extraction units, the effective component contents in effective materials of all the extraction units and effective component contents in the solvents successively are decreased progressively, and its complete extraction process is continuously implemented by stages whose stage number is idential to the number of extraction units, and every unit can respectively independently make extraction operation. When the extraction process of some stage is completed, the unit whose effective component is completely extracted, it can make residue-removing and charging operations.

Description

technical field [0001] The invention relates to a technology for extracting effective ingredients (such as medicinal ingredients) from animals and plants, specifically a continuous countercurrent extraction technology in a dynamic circulation stage, which can be widely used in the fields of pharmacy, chemical industry, food processing and the like. Background technique [0002] The existing traditional Chinese medicine extraction process usually uses extraction methods such as decoction, dipping, and heat reflux. Most of them use a single extraction tank for extraction operations. Generally, 2 to 3 extractions are required. The amount of solvent used is as high as 10 times the weight of the medicinal material. The extraction temperature up to the boiling point of the solvent. Mainly there are the following problems: ①Excessive temperature will lead to the excessive cracking and gelatinization of starch and the loss of azeotropic distillation componen...

AI Technical Summary

Problems solved by technology

The main problems are as follows: ①Excessive temperature will lead to excessive cracking and gelatinization of starch and the loss of azeotropic distillation components in medicinal materials, increasing the content of non-effective components and reducing product quality. It is not suitable for the extraction of heat-sensitive active components.

②A single extraction tank performs multiple intermittent extraction operations and uses a large amount of solvents, not only the production efficiency is low, but also the energy consumption of subsequent concentration is greatly increased. For extraction with organic solvents, the production cost will be greatly increased

③Whether it is decoction, dipping or heat reflux extraction method, the medicinal material and the solvent keep a relatively static state, and the concentration difference of the active ingredient in the medicinal material and the solvent is small when the active ingredient in the medicinal material and the solvent is close to equilibrium, resulting in long extraction time and low extraction rate of the active ingredient. Low cost, waste of valuable medicinal resources, according to Chinese patents 93237130.2 and 98230191.X, even if repeated decoction for 5-8 times, only 50% of the active ingredients can be extracted

In order to improve the extraction rate of active ingredients, it is often used to prolong the extraction time, increase the amount of solvent and increase the extraction temperature, but prolonging the extraction time will affect the production efficiency, and increasing the amount of solvent will increase the production cost

[0003] Chinese patents 95104823.6, 96119720.X, 97247550.8, 98230191.X, 99232171.9, 00219081.8, etc., have introduced extraction techniques and methods such as dynamic, continuous, countercurrent, and ultrasonic waves, which have improved extraction production efficiency and effective ingredient extraction rate to a certain extent, and reduced Production cost, but can not fundamentally further improve the dissolution rate of active ingredients in medicinal materials, reduce the amount of solvent and extraction temperature, the extraction rate of active ingredients is still low, feeding or slag removal is mainly manual, and can not be realized in the true sense. There are many technical problems that are difficult to solve in the implementation process of some technologies and methods, such as the use of organic solvents as extraction solvents, which reduces the safety of the production environment when the fully enclosed extraction operation cannot be realized. The screw type continuous countercurrent extraction is used to shorten the contact time between the material and the solvent, which affects the extraction rate of active ingredients, and the lubricating oil in the mechanical transmission will pollute the extraction solution, etc.

Images