A kind of soft capsule of traditional Chinese medicine composition for treating common cold and preparation method thereof

Abstract

The invention relates to soft traditional Chinese medicine composition capsules for treating cold. The soft traditional Chinese medicine composition capsules for treating cold are characterized in that the ingredients contained in capsule liquid include 30%-50% of traditional Chinese medicine extracts, 40%-70% of dispersing agent, 0%-6% of suspending agent and 0%-4% of wetting agent. The traditional Chinese medicine extracts include a dry extract and volatile oil which are prepared by, by weight, 50-200 parts of forsythia suspensa, 50-200 parts of notopterygium roots, 20-150 parts of mint, 50-200 parts of common andrographis herb, 20-150 parts of Chinese trichosanthes roots and 40-200 parts of dayflower. The soft capsules are produced after a countercurrent extraction process is adopted for extraction, extraction efficiency is high, energy is saved, the produced soft capsules are good in sealing performance, and objectionable odor of the medicines is masked. The soft traditional Chinese medicine composition capsules are good in medicine stability, do not absorb moisture and meanwhile have the advantages of being high in disintegration speed and bioavailability and the like. The virus cold treating effect of the soft capsules is remarkably superior to that of antiviral particles and is further superior to that of a traditional water-soluble preparation.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine pharmacy, in particular to a soft capsule of a traditional Chinese medicine composition for treating colds and a preparation method thereof. Background technique [0002] Flu is a common exogenous disease. According to statistics, adults have 1-3 respiratory diseases per year, and children have 2-7 respiratory diseases per year, most of which are caused by viruses. Influenza not only affects the normal work and life of human beings and endangers health, but also consumes a large amount of expenses accordingly. The harm caused by cold to pregnant women, the elderly and children is also very large, and the complications caused by it, such as pneumonia and secondary infection, have a certain mortality rate. Motherland medicine divides cold into wind-cold and wind-heat cold, and due to the difference of cold types, there are differences in medication. When suffering from wind-cold and co...

AI Technical Summary

Problems solved by technology

[0003] The application number is 200510095620.9, and the prescription titled "a compound preparation for treating colds and its preparation process" is a compound preparation developed on the basis of old traditional Chinese medicine clinical experience. It has been used in the form of decoction in long-term clinical application. The extraction process of this patent is mainly based on water extraction, and the yield of the extract is relatively high; the active ingredients in the prescription are forsythin and other lignan glycosides, and notopterygium in notopterygium is notopterygium alcohol, proscurgic glucoside, and isoeucalyptin. The coumarin compounds represented by procuredin, the andrographolide in Andrographis paniculata paniculata and other medicinal ingredients have poor water solubility, and the medicinal ingredients such as andrographolide have obvious thermal instability, and are easily lost in the traditional heating extraction process , so the content of active ingredients in the water extraction process is low; because the volatile ingredients are relatively unstable in conventional solid preparations and oral liquid preparations (granules, tablets, capsules, powders, pills, syrups, oral liquids, etc.), they are volatile Loss and bad taste

However, traditional extraction methods often have problems such as long extraction period, high heating temperature, and easy destruction of heat-sensitive components, which seriously affect the quality and clinical efficacy of subsequent preparations.

[0004] With the advancement of technology and the development of society, the extraction process of traditional Chinese medicine preparations has the disadvantages of high energy consumption, many impurities, and low efficiency. Low composition and unstable content; traditional dosage forms such as granules and oral liquids have large dosage, serious loss of volatile oil, poor taste, and low bioavailability, which seriously affect the application and sales of the product and restrict people's use of medicine. It is difficult to adapt to the requirements of modern and international Chinese medicine preparations

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