Aceglutamide injection

A technology of acetoglutamine and drug acetoglutamine, applied in the field of acetoglutamine injection, can solve the problems of environment, equipment pollution, life-threatening patients, single dosage form, etc., to avoid cross infection, improve clinical application level and safety properties, subtracting the effect of the dilution process

Inactive Publication Date: 2003-10-01
张嵩
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, only water injections are available in the market, and the dosage form is relatively simple, intramuscular or intravenous injection, and diluted with glucose injection for intravenous injection.
Due to the mixing of l...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 2

[0036] According to the method of example 1-3, it is prepared as raw material with sorbitol instead of glucose. Example 3: Preparation of acetylglutamine injection containing xylitol

example 3

[0037] According to the method of example 1-3, it is prepared as raw material with xylitol instead of glucose. Example 4: Preparation of acetylglutamine injection containing dextran (including large, medium or small molecular weight dextran)

example 4

[0038] According to the method of example 1-3, it is prepared as raw material with dextran instead of glucose. Example 5: Preparation of Acetylglutamine Injection Containing Sodium Chloride

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PUM

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Abstract

An acetylglutamide injection is prepared from the acetylglutamide (0.01-5.00 wt.%) and medicinal carrier (95.00-99.99 wt.%). Its advantages are no need of diluting, and high safety.

Description

technical field [0001] The invention relates to an injection, especially an acetylglutamine injection. Background technique [0002] Acetylglutamine is the acetyl compound of glutamine, which can pass through the blood-brain-spinal fluid barrier; after passing through the blood-brain-spinal fluid barrier, acetylglutamine is decomposed into glutamic acid and γ-aminobutyric acid (GABA). Glutamate is involved in the transmission of information in the central nervous system. γ-aminobutyric acid can antagonize the excitatory toxicological effect of glutamate, improve nerve cell metabolism, maintain nerve stress ability and reduce blood ammonia, and improve brain function. For hepatic encephalopathy and brain trauma, brain neuroma, coma caused by neurosurgery, paralysis, mental decline, memory impairment, senile memory loss, brain function decline, hepatic coma, hemiplegia, high paraplegia, sequelae of poliomyelitis, neurological Headache and low back pain. Acetylglutamine raw ...

Claims

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Application Information

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IPC IPC(8): A61K31/16A61K31/195A61P9/02A61P9/08A61P9/10A61P25/00A61P25/04
Inventor 张嵩
Owner 张嵩
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