Single spray agent of Chinese herbal medicine used as treament and first aid for cardiovascular disease as well as its preparing method

A disease treatment and cardiovascular technology, applied in cardiovascular system diseases, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as obvious side effects and lesions, and achieve stable product quality, good consistency, and advanced preparation methods. Effect

Inactive Publication Date: 2004-03-10
徐黎明 +2
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Problems solved by technology

What needs to be pointed out in particular is borneol, because of its clearing, resuscitating, heat-clearing and pain-relieving effects, it is almost an indispensable adjuvant in Suxiao Jiuxin pills and a considerable part of the preparations. However, borneol is listed as a prohibited ingredient in many countries in the world. The reason is that the side effects are obvious, and there is even the possibility of causing pathological changes

Method used

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Examples

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Embodiment

[0027] Example: take the screened slices of Rhizoma Chuanxiong with a thickness of 2 mm, and soak them in ethanol for 24 hours to fully dissolve the active ingredients in the sliced ​​Rhizoma Chuanxiong. The crude extract of Ligusticum chuanxiong can be obtained in one time by ethanol extraction. The method is to use a 100L concentration unit and a 15KW steam generator to extract according to the conventional process, and the yield can generally reach 30-40%.

[0028] The crude extract of Ligusticum chuanxiong was subjected to CO 2 The supercritical extraction method continued to extract brown oily total alkaloids of Chuanxiong, the extraction temperature was 55°C, the pressure was 6Mpa, and the extraction time was 50 minutes. Generally, 1000g of powdered crude extract of Chuanxiong can get 15-25g of total alkaloids of Chuanxiong.

[0029] The total alkaloids of chuanxiong account for 0.3%, and distilled water accounts for 99.7% by weight to prepare a mixed solution of total ...

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Abstract

A Chinese medicine in the form of spray for the treating and first aid of cardiovascular diseases is prepared from Chuan-xiong rhizome through slicing, immersing in alcohol, extracting to obtain powder, supercritical CO2 extracting to obtain common cnidium base, mixing it with distilled water, and nano emulsifying. Its advantages are high curative effect, no toxic by-effect and convenient application.

Description

technical field [0001] The invention belongs to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a single traditional Chinese medicine spray for cardiovascular disease treatment and first aid and a preparation method thereof. Background technique [0002] Cardiovascular disease mainly refers to coronary heart disease, and the most basic symptom is angina pectoris. There are many kinds of traditional Chinese medicines known to treat cardiovascular diseases, and the commonly used varieties include "Suxiao Jiuxin Pills", "Danshen Dripping Pills" and "Compound Danshen Tablets" and so on. With the development of the modernization of traditional Chinese medicine, transdermal preparations of traditional Chinese medicine for the treatment of cardiovascular diseases, such as the traditional Chinese medicine compound "oral patch" mainly used for first aid and "skin patch" for treatment, have also made significant progress. [0003] The tra...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/12A61P9/10
Inventor 徐黎明吕国树简宝芳
Owner 徐黎明
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