Eureka AIR delivers breakthrough ideas for toughest innovation challenges, trusted by R&D personnel around the world.

Combination of medication for reducing poison and synergic action in radiotherapy or chemotherapy as well as its preparing method

A composition and drug technology, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of target dispersion, unclear active ingredients, and influence on curative effect, so as to block overgrowth and enhance killing Function, cellular immunity and humoral immune function enhancement effect

Inactive Publication Date: 2004-03-10
JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
View PDF2 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Some of this kind of Chinese patent medicines have simple preparation process, unclear active ingredients, and some have scattered targets, which affect the curative effect, etc.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0237] Take astragalus 3.0kg, medlar 1.2kg, ganoderma lucidum 1.2kg.

[0238] For the first time, use 8 times the amount of Astragalus membranaceus, and for the second time, use 6 times the amount of 80% ethanol to reflux extract twice, each time for 2 hours, combine the reflux liquid, filter, recover ethanol, leave the mother liquor for 12 hours, centrifuge, and put the centrifugal liquid on the Treated AB-8 macroporous resin for purification, eluted with 70% ethanol, recovered ethanol, dried to obtain 30 g of total saponins.

[0239] Astragalus dregs, Lycium barbarum, Ganoderma lucidum and other prescription medicines are extracted three times with 12 times the amount of water, each time for 1.5 hours, combined with the decoction liquid, concentrated to a relative density of 1.2 (80°C), ethanol precipitation with an alcohol content of 80%, standing still, and filtering , the precipitate was evaporated to dryness with ethanol, added distilled water to dissolve, centrifuged, t...

Embodiment 2

[0242] Take astragalus 3.0kg, medlar 1.2kg, ganoderma lucidum 1.2kg.

[0243] For the first time, use 8 times the amount of Astragalus membranaceus, and for the second time, use 6 times the amount of 80% ethanol to reflux extract twice, each time for 2 hours, combine the reflux liquid, filter, recover ethanol, leave the mother liquor for 12 hours, centrifuge, and put the centrifugal liquid on the Treated AB-8 macroporous resin for purification, eluted with 70% ethanol, recovered ethanol, dried to obtain 30 g of total saponins.

[0244] Astragalus dregs, Lycium barbarum, Ganoderma lucidum and other prescription medicines are extracted three times with 12 times the amount of water, each time for 1.5 hours, combined with the decoction liquid, concentrated to a relative density of 1.2 (80°C), ethanol precipitation with an alcohol content of 80%, standing still, and filtering , the precipitate was evaporated to dryness with ethanol, added distilled water to dissolve, centrifuged, t...

Embodiment 3

[0247] Take astragalus 4.0kg, medlar 1.5kg, ganoderma lucidum 1.5kg.

[0248] The Astragalus membranaceus of described weight ratio is extracted 4 times with 90% ethanol, each time for 2.5 hours, the ethanol extracts are combined, the ethanol is reclaimed, the liquid after the precipitation is removed is put on the AB-8 macroporous resin column, washed with 80% ethanol Take off, get 40 grams of Astragalus total saponins;

[0249] Combine the Lycium barbarum and Ganoderma lucidum in the weight ratio with the above-mentioned ethanol-extracted Astragalus residue, add 10 times the amount of water, decoct 4 times, each time for 2 hours, combine the decoction liquid, concentrate to a relative density of 1.3, add ethanol to make the When the alcohol content reaches 70%, filter the precipitate, dry the precipitate, add water to dissolve it, concentrate the water to a relative density of 1.1, add ethanol to make the alcohol content reach 70%, filter the precipitate, and dry to obtain 1...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A detoxicating synergistic Chinese medicine for radiotherapy or chemicotherapy is prepared from astragalus root, wolfberry fruit and ganoderma. Its advantage is high curative effect.

Description

technical field [0001] The invention relates to a medicine for reducing toxicity and enhancing efficacy of radiotherapy and chemotherapy and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Malignant tumors are common and frequently-occurring diseases in my country. At present, almost all anticancer drugs belong to the category of cytotoxicity. While killing tumor cells, anticancer drugs also seriously damage normal tissues. This unavoidable side effect limits the application and efficacy of anticancer drugs. . A few days ago, the common drugs used in the market for reducing toxicity and increasing the efficacy of radiotherapy and chemotherapy include ribonucleic acid, Chinese patent medicines such as Zhenqi Fuzheng Granules, Yunzhi Polysaccharide Capsules, and Jinghuangzhi Oral Liquid (Shaanwei Yaozhunzi (1993 No. 001612)), etc. . Some of these proprietary Chinese medicines have simple preparation proces...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61P37/02
Inventor 段金廒贾晓斌彭蕴茹
Owner JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com