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Nano magnetic particle in vivo collector and collecting method

A nano-magnetic and granular technology, which is applied in the directions of magnetic therapy, electrotherapy, and suction devices, etc., to achieve the effect of easy implementation

Inactive Publication Date: 2004-12-15
SOUTHEAST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] For the separation of magnetic particles, the method of high gradient magnetic field separation is generally adopted, that is, the external gradient magnetic field is applied to make it precipitate, and the magnetic material or magnetic liquid is injected into the body, which has a good application prospect in both diagnosis and treatment. Magnetic substances are taken out to avoid some unknowable effects, which is still an unresolved problem

Method used

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  • Nano magnetic particle in vivo collector and collecting method
  • Nano magnetic particle in vivo collector and collecting method

Examples

Experimental program
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Embodiment

[0027] We experimented with a multi-layer chitosan film wrapped with ordinary iron wire.

[0028] Take an ordinary iron wire with a diameter of 1mm, immerse it in the chitosan-citric acid solution, pull it out evenly, then dry it naturally, repeat this many times, and finally dry it.

[0029] Put the iron wire into the Fe 3 o 4 In the test tube of the solution, an external magnetic field of 200KA / m is generated by an air-gapped electromagnet. After a while, a thicker layer of particles can be observed gathering around the wire.

[0030] A vacuum pump is connected to the back end of the tube to extract negative pressure to remove the particles.

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Abstract

The present invention relates to one auxiliary clinical device for purifying blood and body fluid in tumor treatment. The in vivo collector consists of negative attractor port, canal, canal cavity, protecting lattice outside fine filament, macroporous membrane and ferromagnetic fine filament. During collection, the canal with inside ferromagnetic fine filament is inserted into target organ or blood vessel and homogeneous magnetic field is applied to the perpendicular direction of the ferromagnetic fine filament, so that nano magnetic grains are adsorbed to ferromagnetic fine filament and pumped out via negative pressure attraction with the in vivo negative pressure attractor connected to the port of the attracting end.

Description

technical field [0001] The invention relates to a blood / body fluid purification clinical tumor treatment auxiliary equipment and an operation method, which belong to the technical field of medical equipment manufacturing. Background technique [0002] The hyperthermia effect of ferrofluid in tumors is one of the hot spots in the application of nanoscience in the field of biomedicine. At present, there are clinical devices made according to this principle in the world. However, the magnetic particles still remain in the human body after treatment, and there is no effective evidence that they can be naturally metabolized by the human body. Therefore, it is a very practical problem to remove the magnetic particles after treatment. [0003] Because the size of the sol particles we use is nanoscale, the usual methods for filtering particles from suspensions are generally aimed at larger (greater than 1 micron) particles. There are no methods and measure...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/00A61M25/00A61N2/10
Inventor 顾宁孙剑飞张宇
Owner SOUTHEAST UNIV