Instant agent of donkey-hide gelatin and preparation method

A technology of donkey-hide gelatin and granules, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, powder delivery, etc., can solve the problems such as the auxiliary pressure does not meet the conventional requirements, it is difficult to produce qualified products, and the donkey-hide gelatin is inconvenient to take, etc. Easy to control quality, low cost, good meltability and taste

Active Publication Date: 2005-03-30
FUJIAO GROUP CORP SHANDONG
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AI Technical Summary

Problems solved by technology

[0002] Donkey-hide gelatin is a kind of traditional Chinese medicine. Traditional donkey-hide gelatin is in the form of flakes. When taking it, it needs to be processed into small pieces. The production process is to make donkey skin into a thick paste through a series of complex processes such as selection, washing, hair removal, cutting, decoction, and concentration, and then spray-dry to make granules. During the production process, the conditions are not easy to control, and in During the process of spray drying and boiling granulation, wall sticking is easy to occur, and the yield is very low
CN1119527A discloses a preparation method of granular donkey-hide gelatin, deer antler and turtle glue, but the spray pressure used in the preparation method is 0.2-0.35mpa, the auxiliary pressure is 0.015-0.025mpa, the auxiliary pressure does not meet the conventional requirements, and lacks negative pressure indicators , it is difficult to produce qualified products

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1, a kind of instant donkey-hide gelatin granules is a pharmaceutical preparation prepared by using the following process as a raw material of donkey-hide gelatin,

[0021] a. Glue powder preparation: pulverize donkey-hide gelatin blocks (with a water content of 5-15%) into a fine powder with a particle size of 100 mesh.

[0022] B. Boiling granulation: put the donkey-hide gelatin powder into the raw material container of the boiling granulator, add the purified water of 2-3% donkey-hide gelatin weight as the binding agent and carry out boiling granulation, the spray pressure is 0.30Mpa, and the auxiliary spray pressure is 0.13Mpa, the negative pressure is 4000pa. The standard for making granules is that the sum of granules and powders that cannot pass through No. 1 sieve and No. 4 sieve shall not be higher than 8%;

[0023] c. Drying: Place the qualified particles in an oven at 105°C to dry and sterilize until the moisture content does not exceed 5%;

[00...

Embodiment 2

[0025] Embodiment 2, basic technique is the same as embodiment 1 but binding agent is the glue juice that contains donkey-hide gelatin 5%.

Embodiment 3

[0026] Embodiment 3, basic technique is the same as embodiment 1 but spraying pressure is 0.25Mpa when boiling granulation, auxiliary spraying pressure is 0.10Mpa, and negative pressure is 3000pa.

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PUM

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Abstract

An instant donkey-hide gelatin in the form of particles is prepared from donkey-hide gelatin through pulverizing, granulating and baking.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to an instant granule preparation and a preparation method thereof. Background technique [0002] Donkey-hide gelatin is a kind of traditional Chinese medicine. Traditional donkey-hide gelatin is in the form of flakes. When taking it, it needs to be processed into small pieces. The production process is to make donkey skin into a thick paste through a series of complex processes such as selection, washing, hair removal, cutting, decoction, and concentration, and then spray-dry to make granules. During the production process, the conditions are not easy to control, and in In the process of spray drying and boiling granulation, wall sticking is easy to occur, and the yield is very low. CN1119527A discloses a preparation method of granular donkey-hide gelatin, deer antler and turtle glue, but the spray pressure used in the preparation metho...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/14A61K35/36A61P7/06
Inventor 王京娥杨福安周广森黄长勇
Owner FUJIAO GROUP CORP SHANDONG
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