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Medicine for treating male infertility

A male infertility drug technology, applied in the field of drugs for the treatment of male infertility, can solve the problems of dryness and heat, low effective rate, unsuitable for long-term use in the treatment of infertility, and achieve the goal of improving male function and mild drug properties Effect

Inactive Publication Date: 2005-07-06
广州华博生物制药研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0017] The purpose of the present invention is to overcome the disadvantages of poor curative effect and low effective rate of existing medicines and the shortcomings of traditional Chinese medicines for strengthening yang, although they have aphrodisiac effects but are dry and hot, not suitable for long-term use, and have poor efficacy in treating infertility, and provide a curative effect Good, highly effective, safe and low-toxic drug for treating male infertility that can be taken for a long time

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] The preparation of embodiment 1 capsule

[0047] prescription:

[0048] Curculigo 10g Epimedium 20g Raspberry 15g

[0049] Leek seeds 15g Cuscuta 20g Goji berries 15g

[0050] Plantago 15g Schisandra 10g Mulberry 15g

[0051] Codonopsis 20g, Danshen 20g, licorice 6g

[0052] Made into 30g

[0053] The production method of its preparation

[0054] Take licorice powder, sieve 100 mesh for later use, take the remaining 11 traditional Chinese medicines, add water to decoct twice, each time for 2 hours, combine the decoction, filter, low-temperature vacuum concentration to a relative density of 1.26 (60°C), let cool, Add ethanol until the alcohol content is 55-60%, let it stand for 12-24 hours, take the supernatant to recover ethanol, concentrate to a thick paste, add the above powder, mix, dry at low temperature, and powder through 100 mesh (mesh, that is, per square centimeter number of holes) sieve, add auxiliary materials to the ...

Embodiment 2

[0055] The preparation of embodiment 2 tablet

[0056] Remove salvia miltiorrhiza in the prescription, all the other are with embodiment 1

[0057] The production method of its preparation is the same as in Example 1 before powdering through a 100-mesh sieve, adding talcum powder and magnesium stearate in an appropriate amount, and tableting with a tablet machine, each weighing 0.5g.

Embodiment 3

[0058] The preparation of embodiment 3 decoction (being oral solution)

[0059] prescription:

[0060] Curculigo 4g Epimedium 10g Raspberry 5g

[0061] Leek seeds 30g Cuscuta seeds 40g Goji berries 30g

[0062] psyllium 5g, schisandra 4g, mulberry 5g

[0063] Codonopsis 40g, Salvia miltiorrhiza 40g, licorice 20g

[0064] All the medicines in the prescription are submerged in water and decocted 3 times. The amount of water used each time is 6 times, 4 times, and 3 times the weight of Chinese herbal medicines respectively, and the decoctions are combined three times to obtain a decoction.

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Abstract

Disclosed is a medicine for treating male infertility, which mainly comprises curculigo rhizome, epimeddium, raspberry, leek seeds, dodder seed, wolferry fruit, plantain seeds, schisandra fruit, mulberry seeds, pilose asiabell root, and licorice root. The medicine is made into the dosage form of oral liquid.

Description

technical field [0001] The invention relates to a medicine for treating male infertility, which belongs to the field of traditional Chinese medicine. Background technique [0002] According to statistics, about 15% of married couples are infertile, and about 50% of them are caused by the man. According to foreign research, the sperm density of male testes has dropped by about 50% in the past 50 years. [0003] Sperm counts among American men have fallen by almost a third over the past half-century, according to research by Ralph Doherty of Florida State University. The median sperm count in 1929 was 90 million / ml and in 1979 it was 60 million / ml. [0004] From the perspective of biological characteristics of sperm, sperm is the terminal product of the development of the male germ line. In the process of spermatogenesis, formation and deformation, due to the escape of cytoplasm, the DNA repair enzymes in the cytoplasm are lost, resulting in the loss of the function of the D...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61P15/10
Inventor 黄清春吴新荣韩丽萍李俭洪赵树进
Owner 广州华博生物制药研究所
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