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Injection of manchurian wildginge and astragalus root and its preparing method

A technology of Xinqi injection and injection liquid, which is applied in the field of Xinqi injection, can solve the problems of few types of injections, low bioavailability of oral preparations of traditional Chinese medicine, and unsatisfactory effects, etc., and achieve fast drug effect, enhanced pharmacological activity, and fast development Effect

Inactive Publication Date: 2010-04-28
四川三民药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, there are many drugs clinically used for cardiovascular and cerebrovascular diseases and pulmonary hypertension, and chemical drugs are mainly used to control symptoms. Most of traditional Chinese medicines are oral preparations, and there are few types of injections. The bioavailability of oral preparations of traditional Chinese medicines is low, and the effect is not ideal.

Method used

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  • Injection of manchurian wildginge and astragalus root and its preparing method
  • Injection of manchurian wildginge and astragalus root and its preparing method
  • Injection of manchurian wildginge and astragalus root and its preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment A

[0044] Embodiment A small capacity Xinqi injection

[0045] It consists of 3-12g extract (intermediate) of breviscapine, 10-40g extract (intermediate) of Radix Astragali, and 5-20ml of water for injection.

[0046] Example 1 consists of 3 g of Erigeron breviscapus extract (intermediate), 10 g of Astragalus extract (intermediate), and water for injection added to 5 ml.

[0047] Example 2 consists of 6 g of Erigeron breviscapus extract (intermediate), 20 g of Astragalus extract (intermediate), and water for injection added to 10 ml.

[0048] Example 3 consists of 12 g of Erigeron breviscapus extract (intermediate), 40 g of Astragalus extract (intermediate), and water for injection added to 20 ml.

[0049] Contain sodium chloride big infusion and prepare finished product by following method

[0050]Take 3-12g extract (intermediate) of Erigeron breviscapine and 10-40g extract (intermediate) of Radix Astragali, add about 20% water for injection, adjust the pH value to about 7.0 w...

Embodiment B

[0051] Embodiment B Large-capacity Xinqi Sodium Chloride Injection

[0052] It consists of 3-12g extract (intermediate) of breviscapine, 10-40g extract (intermediate) of Radix Astragali, 0.9% sodium chloride in the total amount of the injection, and 50-200ml of water for injection.

[0053] Example 1 consists of 3 g of Erigeron breviscapus extract (intermediate), 10 g of Astragalus extract (intermediate), 0.45 g of sodium chloride, and water for injection added to 50 ml.

[0054] Example 2 consists of 6 g of Erigeron breviscapus extract (intermediate), 20 g of Astragalus extract (intermediate), 0.9 g of sodium chloride, and water for injection added to 100 ml.

[0055] Example 3 consists of 12 g of Erigeron breviscapus extract (intermediate), 40 g of Astragalus extract, 1.8 g of sodium chloride, and 200 ml of water for injection.

[0056] Glucose-containing infusion is prepared into a finished product as follows:

[0057] Take 3-12g of Erigeron breviscapine extract (intermed...

Embodiment C

[0058] Embodiment C Large-capacity Xinqi Glucose Injection

[0059] It consists of 3-12g extract (intermediate) of breviscapine, 10-30g extract (intermediate) of astragalus, 5% glucose in the total amount of the injection, and 50-200ml of water for injection.

[0060] Example 1 consists of 3 g of Erigeron breviscapus extract ((intermediate), 10 g of Astragalus extract (intermediate), 2.5 g of glucose, and water for injection added to 50 ml.

[0061] Example 2 consists of 6 g of Erigeron breviscapus extract (intermediate), 20 g of Astragalus extract (intermediate), 5 g of glucose, and water for injection added to 100 ml.

[0062] Example 3 consists of 12 g of Erigeron breviscapus extract (intermediate), 40 g of Astragalus extract (intermediate), 10 g of glucose, and water for injection added to 200 ml.

[0063] Example 4 consists of 9 g of Erigeron breviscapus extract (intermediate), 30 g of astragalus extract (intermediate), 7.5 g of glucose, and water for injection added to ...

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PUM

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Abstract

A Chinese medicine in the form of injection, perfusion, or powder injection for treating ischemic cerebral apeplexy and its sequelae, and pulmonary hypertension is prepared from shortscape fleabane herb, astragalus root, medicinal auxiliaries and the water for injection. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a kind of invigorating qi and activating blood, benefiting the heart and unblocking the brain, soothing collaterals and relieving pain, which is used for treating chest pain and heart pain syndrome (angina pectoris of coronary heart disease) caused by deficiency of righteous energy and blood stasis and arterial obstruction, ischemic cerebral apoplexy and apoplexy caused by stroke. Xinqi Injection, a new drug for pulmonary arterial hypertension with stroke sequelae and phlegm-retained lung inflation syndrome. Another object of the present invention is to extract and purify the effective components of Erigeron breviscapus and Radix Astragali, and add appropriate amount of pharmaceutical excipients to make small-capacity Xinqi injection, large-capacity Xinqi sodium chloride injection, and large-capacity Xinqi sodium chloride injection suitable for intravenous infusion. Xinqi Glucose Injection, Xinqi for Injection (lyophilized powder...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/481A61K36/28A61K9/08A61K9/19A61P9/10
Inventor 罗明生
Owner 四川三民药业有限公司