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Osteoporosis treating compound Chinese preparation and its preparing process

A technology for osteoporosis and compound preparations, which is applied in the fields of pharmaceutical formulas, medical preparations containing active ingredients, bone diseases, etc.

Active Publication Date: 2006-11-08
YANGZIJIANG PHARMA GROUP SHANGHAI HAINI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the medicines for the treatment of osteoporosis at home and abroad are mainly western medicines, but western medicines all have different degrees of side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment one is the preparation of Chinese medicine granule a of the present invention:

[0034] 1. Weigh each component according to the following weight ratio:

[0035] Rehmannia glutinosa 627g, Chinese yam 313g, medlar 209g, Eucommia ulmoides 313g, dodder 209g, curculigo 167g, codonopsis 125g, astragalus 209g, salvia miltiorrhiza 209g, vinegar yanhusuo 105g, calcined oyster 313g.

[0036] 2. According to the above ratio, weigh ten kinds of medicinal materials except curculigo, Rehmannia glutinosa, etc., add water and decoct three times. The decoction time is 3 hours for the first time, 1 hour for the second and third times, and 7 times the amount of water for each of the three times. . Filtrate the decoction to obtain the filtrate, concentrate the filtrate to a clear paste with a relative density of 1.18-1.20 (65-70°C), cool to room temperature, add ethanol until the alcohol content is 50%, stir evenly, place for 48 hours, filter After that, supernatant I was obt...

Embodiment 2

[0040] Embodiment two is the preparation of Chinese medicine granule b of the present invention:

[0041] 1. Weigh each component according to the following weight ratio:

[0042] Rehmannia glutinosa 600g, yam 280g, medlar 200g, Eucommia 280g, dodder 180g, curculigo 200g, codonopsis 150g, astragalus 200g, salvia miltiorrhiza 200g, vinegar yanhusuo 100g, calcined oyster 300g;

[0043] 2. Weigh curculigo, salvia miltiorrhiza, astragalus and Codonopsis pilosula according to the above weight ratio, and extract three times with 70% ethanol under reflux, the first time is 2 hours, the second and third time are 1 hour, the amount of solvent is 8 times the first time, and the second time is 1 hour. Two and three times are each 6 times the amount, filter, and combine the filtrates to obtain an alcohol extract, reclaim ethanol, and obtain the active ingredient I;

[0044] 3. Weigh the rest of Rehmannia glutinosa and other 7 medicinal materials according to the above weight ratio, add w...

Embodiment 3

[0047] Embodiment three is the preparation of Chinese medicine capsule of the present invention:

[0048] According to the method described in Example 1, the obtained extract was granulated according to a conventional method, and filled into capsules, each 0.3g, and each g of medicinal powder was equivalent to about 2.8g of raw medicinal materials.

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PUM

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Abstract

The present invention discloses a kind of osteoporosis treating compound Chinese preparation and its preparation process. The osteoporosis treating compound Chinese preparation has the alcohol and / or water extracts of 11 kinds of Chinese medicinal materials, including prepared rhizome of rehmannia, Chinese yam, wolfberry fruit, eucommia bark, dodder seed, etc in certain weight proportion, as the active components. The extracts are mixed and added with proper amount of supplementary material to prepare required preparation form. The Chinese preparation has the functions of nourishing liver and kidney, benefiting Qi and promoting blood circulation, is used in treat primary osteoporosis, and has determined curative effect, use safety, stable quality and high effective rate.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating osteoporosis and a preparation method thereof. Background technique [0002] Osteoporosis (Osteoporosis) is a common metabolic bone disease. With the increase of the aging society, osteoporosis will also become one of the problems of public health worldwide. At present, the medicines for the treatment of osteoporosis at home and abroad are mainly western medicines, but western medicines all have side effects in varying degrees. In addition, the onset of osteoporosis is a multi-factor, multi-target systemic disease, and Western medicine treatment is mostly alternative therapy. Contents of the invention [0003] The invention provides a traditional Chinese medicine compound preparation for treating osteoporosis and a preparation method thereof. [0004] The present invention is a traditional Chinese medicine compound preparation for treating osteoporosis, which ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K35/618A61P19/10
Inventor 陆宏国吴沉顾孝红魏春燕
Owner YANGZIJIANG PHARMA GROUP SHANGHAI HAINI PHARMA
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