Use of ginkgoic acid in use for killing Oncomelania snail distilled from outer seed coat of gingkgo

A technology of Ginkgo biloba testa and ginkgolic acid, which is applied in the field of plant molluscicides, can solve the problems of no research reports on molluscicide effects, and achieve the effects of good molluscicide effects, abundant resources, and low fish toxicity

Inactive Publication Date: 2006-12-06
JIANGSU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Ginkgo biloba contains ginkgolic acid, which is the main active ingredient with insect...

Method used

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  • Use of ginkgoic acid in use for killing Oncomelania snail distilled from outer seed coat of gingkgo

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Ginkgo biloba testa is used as raw material, and the steps are as follows: After the dry ginkgo biloba is crushed, add an appropriate amount of petroleum ether for reflux extraction, and the extract is concentrated under reduced pressure to obtain a crude extract; the crude extract is separated by silica gel column chromatography, petroleum ether- Elute with ether-formic acid, or use macroporous resin to absorb and separate, collect ginkgolic acid components, concentrate to dryness, and obtain a gingkgolic acid mixture with a purity of more than 85%; the ginkgolic acid mixture is dissolved in a co-solvent aqueous solution to make a molluscicide , the plant molluscicide is milky white liquid, wherein the content of ginkgolic acid is not less than 3g / L. Dilute with water to a concentration of 6.66mg / L liquid medicine.

Embodiment 2

[0016] Embodiment 2: The same method as above, diluted with water to a concentration of 3.33mg / L liquid medicine.

Embodiment 3

[0017] Embodiment 3: the same method as above, diluted with water to a concentration of 1.67mg / L liquid medicine.

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PUM

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Abstract

An insecticide for killing oncomelania is prepared from the external seed vessel of gingko through reflux extracting in petroether, alcohol, or ether, vacuum concentrating, separating and purifying by macroreticular resin or chromatography with silicon gel column to obtain the ginkgolic acid mixture, and dissolving it in the aqueous solution of cosolvent.

Description

technical field [0001] The invention belongs to a plant molluscicide, in particular to the use of ginkgolic acid extracted from the outer testa of ginkgo biloba for killing amphibious snails. Background technique [0002] Schistosomiasis is a major infectious disease that seriously endangers people's health and life safety and affects economic and social development. Oncomelania is the only host of schistosomiasis. If snails are eliminated, schistosomiasis will not spread and become popular. Therefore, to achieve the goal of eradicating schistosomiasis by eliminating snails has always been an important strategy and measure for schistosomiasis control in many schistosomiasis-endemic countries. At present, sodium pentachlorophenate and niclosamide are commonly used to kill snails in various countries in the world. Sodium pentachlorophenate has good molluscicidal effect. 50 It is 0.54mg / L. It was once used as a main molluscicide in my country, but its production and use have b...

Claims

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Application Information

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IPC IPC(8): A01N37/10A01P9/00
Inventor 吴向阳仰榴青陈钧
Owner JIANGSU UNIV
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