126 results about "Oncomelania" patented technology

A blood fluke infectious oncomelania detection kit and a detection method thereof belongs to the verminosis transmission medium detecting field. The invention provides a kit and a detection method for detecting blood fluke infectious oncomelania based on a loop-mediated isothermal DNA amplification technology (LAMP). According to the LAMP technology principle, six pairs of specific primers for amplifying a DNA fragment between the 20bp and 231bp of the schistosoma japonicum non-long terminal repeated inverse transcription transposon gene (AF412214) are designed. The LAMP method is constructed for detecting blood fluke gene in the body of the infectious oncomelania and the objective for distinguishing the blood fluke infectious oncomelania from the non-infectious oncomelania is reached. Comparing to the conventional blood fluke infectious oncomelania detection method the method of the invention has advantages of easy and fast operation, sensitive and specific without especial equipment and is suitable for bilharziasis controlling personnel use on site.

An insecticide for killing oncomelania is prepared from the external seed vessel of gingko through reflux extracting in petroether, alcohol, or ether, vacuum concentrating, separating and purifying by macroreticular resin or chromatography with silicon gel column to obtain the ginkgolic acid mixture, and dissolving it in the aqueous solution of cosolvent.

The invention relates to application of a sanguinarine or a chelerythrine for preventing and curing of schistosomiasis. The invention applies the sanguinarine and the chelerythrine on killing an oncomelania, a snail egg, a Japanese blood fluke cercaria, a schistosome and the prevention and cure of schistosomiasis. The inventor discovers that the sanguinarine or the chelerythrine can kill the oncomelania and the snail egg safely and effectively and can kill the Japanese blood fluke cercaria as well as a schistosomulum and an imago of the schistosome under a lower concentration, which has the functions of preventing and curing the schistosomiasis and does not pollute the environment.

The usage of botanical molluscicide and tea saponin belongs to the technical field of agricultural chemical. The molluscicide is characterized by containing 15-30% of tea saponin, 8-15% of dispersant and 55-75% of filling agent, wherein, the dispersant is dodecyl sodium sulfate or nekal, and the filling agent is calcium bicarbonate or white carbon black. The botanical molluscicide takes the tea saponin as a main material so that the botanical molluscicide has low toxicity, quick results and good mollusk killing effect, and can kill pomacea canaliculata, oncomelania, and shell snails and field snails which damage cotton, soy beans and vegetables, and can be made into a wettable powder; and the cost of material is low. The tea saponin can be used for preparing pesticides for killing mollusks, such as pomacea canaliculata, oncomelania, shell snails and field snails.

The invention relates to the use of ginkgoic acid in preparation of biological pesticide for killing Oncomelania snail and preventing schistosomiasis, wherein experiment result shows that, the ginkgolic acid can effectively inhibit key enzyme and de-coupling reaction to mitochondria oxidation phosphorylation in mollusk energy supply biochemical metabolism, effectively inhibit tyrosinase during insect exuviation procedure and prostaglandin synthetase during breeding process, thus can eradicate unwanted mollusk harming agronomic crops.

The invention discloses a fluorescence quantitative PCR reagent box for rapid detection of Schistosoma japonicum, relates to gene detection technology of a kind of pathogen of zoonotic infectious disease, suitable for qualitative and quantitative detection of Schistosoma japonicum. The invention comprises of DNA extracting solution, fluorescence quantitative PCR reaction solution, standard positive template PU-SJ and negative quality control standard sample; the fluorescence quantitative PCR reaction solution contains specific primers and fluorescence probe of Schistosoma japonicum. The invention was accurate in quantitative detection, quick with good specificity and high sensitivity; can identify and detect Schistosoma japonicum and Chinese schistosomiasis; the steps are simple with good repeatability; can qualitatively and quantitatively detect the DNA samples of all three species of Schistosoma japonicum group, can replace traditional aetiology methods, oncomelania crushing method of detecting the snail of schistosome cercariae and larva escape method.

The invention relates to a Xanthobacter and its snail killer. A snail bacterium, namely Xanthobacter autotrophicus is a Xanthobacter autotrophicus II whose collection unit. It uses beef peptone agar plate or slope culture medium to separate bacterial strains, obtains snail-killing Xanthobacter autotrophicus solution (a hundred million grades / ml) by bottle-shaking fermentation process; and the application of Xanthobacter autotrophicus as a snail killer is that: making ultrasonic processing on the Xanthobacter autotrophicus solution and plant material forming agent, then mixing them to prepare a novel biological snail killer, which has the characters: (1) quickly killing the snail, and effectively preventing the snails from climbing up to flee; (2) harmless to non-target living things and fish, fast to naturally degrade and no pollution; (3) no toxic and side effect, and time of maintaining snail-killing pesticide effect 15 days long; (4) convenient to store, transport and use; etc.

The invention relates to a method and a device for killing snails. By applying a. a snail killing pad for restraining plant growing and preventing snails from getting in and out of earth, b. a snail breeding ground with large water change, and a separation device, the snails are prevented from moving with water level so as to obtain a suitable breeding environment and further kill the snails; By covering the snail killing pad, the snails can not obtain necessary wet earth for living and vegetation for hiding and eating. During flood season, the separation device can prevent the snails on water side from moving with the water level and cause the snails to be drowned; during water withdrawal, the snails can not move with water level to a suitable breeding ground due to the existing of the separation device and then die. The separation device can be a separating channel, floating separating matters, as well as separating nets, separating boards or separating cloth with fixed support structures. According to different environments and snail breeding grounds, the snail killing pad and the separation device, or the snail killing pad and the separation device can be adopted for killing the snails. The snail killing pad, the floating separation device, etc. can contain drugs for killing and expulsing snail and other drugs.

A composite insecticide in the form suspension for killing oncomelania is prepared from teniarene, chlorphoxim, wetting agent, disperser, viscosity regulator, antiseptic, defoaming agent, and water through proportional mixing, and ball grinding.

The invention discloses niclosamide phosphate ester, a pharmaceutically acceptable salt thereof, and application of the niclosamide phosphate ester serving as a soluble pro-drug of niclosamide in preparing correlative medicaments. The niclosamide phosphate ester has a general formula of I or II. The niclosamide phosphate ester and the pharmaceutically acceptable salt thereof have good water solubility, and can be used for producing niclosamide parent drugs through metabolism. Thus, the niclosamide phosphate ester and the pharmaceutically acceptable salt can be used as water-soluble oncomelania-killing medicaments (for treating schistosomiasis), water-soluble human and livestock tapeworm expelling medicaments, and novel antineoplastic medicaments.

The invention provides an intelligent oncomelania detection, recognition and statistics system. The system comprises a CT image acquisition module, an image automatic detection module and a data analysis and processing module. The CT image acquisition module is used for acquiring a to-be-detected high-definition soil sample three-dimensional image containing oncomelania, namely an oncomelania CT image, and sending the oncomelania CT image to the image automatic detection module; the image automatic detection module is used for carrying out image preprocessing on the collected CT image of the oncomelania and then detecting the oncomelania by utilizing an automatic screw recognition and detection algorithm; and the data analysis and processing module is connected with the image automatic detection module and is used for counting the number and types of the detected oncomelania according to the detection result of the image automatic detection module and giving out the distribution condition of the oncomelania. According to the invention, the recognition and detection rate of oncomelania in the collected image can be improved, and the whole set of system is based on portable equipment, so that the general personnel who do not receive blood defense education can complete image collection and oncomelania detection and statistical operation.

The invention discloses an intelligent oncomelania and oncomelania living environment monitoring system based on a wireless sensor network. Oncomelania coverings in a responsible monitoring water area of each front-end subsystem are stirred and removed and then image acquisition is conducted, and environmental information of the water areas is acquired and sent to a cluster head node of a middle communication conversion subsystem in a wireless mode; the environmental information is sent to the same secondary aggregation node in a wireless mode, and data are forwarded to a server of a terminal processing statistic early-warning issuing subsystem through the secondary aggregation node via a connected router; the server of the terminal processing statistic early-warning issuing subsystem conducts image processing, image recognition and image understanding, a value is compared with a danger warning threshold value, related early-warning broadcast is given, the data are issued to a connected client, and then working staff on a client side can look over the data and issue related commands for processing. The system has the advantage that the oncomelania distribution situation of key water areas can be remotely monitored in real time.

The invention relates to niclosamide ethanolamine salt nano suspending agent for killing oncomelania and its preparation method, belongs to oncomelania-killing drug and insoluble drug nano preparation technology field. The method comprises steps of adding dimethyl sulphoxide to stablizer 1%-10% in mass content and niclosamide ethanolamine salt 5%-25% in mass content and mixing ,confecting solution, obtaining niclosamide ethanolamine salt nano suspending agent stock solution, adding it to aqueous solution when stirring niclosamide ethanolamine salt content being 0.01%-1%, niclosamide ethanolamine salt grain size being 50nm-1 mum, obtaining niclosamide ethanolamine salt nano suspending agent. The inventive method can make water-insoluble niclosamide ethanolamine salt disperse well in waterbody. The solution can be used while being prepared. The inventive niclosamide ethanolamine salt nano suspending agent is simply prepared, and promote bioavailability while meet the need of killing snail and reduce the toxicity to fish.

The invention discloses oncomelania killing medicine of a niclosamide ethanolamine particle preparation and a preparation method thereof. The particle preparation consists of the following ingredients in percentage by mass: 1 percent to 20 percent of niclosamide ethanolamine, 0.1 percent to 2.0 percent of wetting agents, 0.1 percent to 3.0 percent of dispersing agents, 0.01 percent to 0.2 percent of binding agents and the balance carriers. The oncomelania killing effect of the niclosamide ethanolamine is enhanced, the use is convenient, the pollution is reduced, and the particle preparation is favorable for laying the foundation for further controlling the schistosomiasis during the oncomelania killing in dry and waterless marshland.

The invention discloses an oncomelania-and-schistosoma-preventing water bank zone revetment structure. The oncomelania-and-schistosoma-preventing water bank zone revetment structure is characterized in that a herbaceous plant isolation area is arranged below the high water level of a revetment, a soil-fixing erosion-preventing dike dam area is arranged above the high water level of the revetment, and a woody plant oncomelania-expelling area is arranged on one side, far away from water, of the outside of the soil-fixing erosion-preventing dike dam area. Oncomelania-preventing water-tolerant herbaceous plants are planted below the normal water level of the herbaceous plant isolation area, oncomelania-preventing hygrocolous herbaceous plants are planted at the position above the normal water level and below the high water level, and the wide close-planting mode is adopted by all the plants. The soil-fixing erosion-preventing dike dam area is laid with ecological revetment bricks in a building mode, and the width of the soil-fixing erosion-preventing dike dam area is 2-3m. The woody plant oncomelania-expelling area is of a forest belt structure which is composed of hygrocolous trees and hygrocolous shrubs in a mixed mode, and the purpose of tall-and-short matching, the purpose of space combination, the purpose of complementation between the advantages and the disadvantages, and the purpose of oncomelania-expelling symbiosis can be achieved. According to the oncomelania-and-schistosoma-preventing water bank zone revetment structure, perfect combination between water bank zone water conservancy engineering and forestry schistosoma prevention is achieved through thorough engineering design and scientific plant arrangement, and the oncomelania-and-schistosoma-preventing water bank zone revetment structure can play a remarkable role in expelling oncomelania and preventing schistosoma, and can have the advantages of being ecological and attractive, improving the effect, and being multifunctional.

The invention provides a camptothecin plant molluscacide and a preparation and application method thereof. The crystalline powder of the camptothecin is prepared into 0.05-0.1g / L of molluscacide aqueous solution and molluscacide pelletized granule with camptothecin content of 0.25-0.30 percent. The camptothecin plant molluscacide is pure chemical component and meets the requirement of environmental protection, and the oncomelania control effect of the Camptothecin plant molluscacide can be evaluate in a standardized way; and the invention has good effect of expelling and killing the oncomelania and also has the advantages of simple manufacturing process, lower cost, convenient storage and transportation, no pollution to the environment, no harm to human, animals and fish and obvious economic benefit, social benefit and ecological benefit.

The invention discloses a novel environment-friendly oncomelania killing granule capable of being sprayed and a preparation method thereof. The granule is composed of the following components in percentage by mass: 0.1%-30% of oncomelania killing effective components, 0.1%-3% of dispersant, 0.1%-2% of wetting agent, 0.1%-10% of compound bonding agent and the balance of carrier fine sand. According to the novel environment-friendly oncomelania killing granule capable of being sprayed, intrinsic substances in rivers are selected as base materials; a sand-based granule which has moderate mass, has less influences on production and application equipment and can be slowly released for a long time is provided, so that the problems in the aspects of a production formula and a processing process are successively solved; the invention provides an energy-saving, efficient and environment-friendly novel oncomelania killing product which is suitable for being used in all schistosome prevention regions, and has significant values in the aspects of society, environmental conservation and economy.

The invention provides a floating oncomelania blocking device with clamping grooves, which is arranged in an oncomelania sinking tank, and comprises oncomelania blocking walls and clamping grooves which are respectively arranged on the two side walls of the oncomelania sinking tank, wherein the oncomelania blocking walls are respectively inserted in the clamping grooves, and the height of the oncomelania blocking walls is 0.5-0.6m. The device utilizes the clamping grooves and the floating oncomelania blocking walls to replace the traditional bricking concrete wall, when the water flow which contains oncomelania passes by the oncomelania blocking walls, floaters on the water surface can be blocked so that oncomelania is prevented from being spread to the downstream along with the water flow; and moreover, the oncomelania blocking walls can float up and down along with the water level, so the technical problem of an overlarge current-obstruction area under the conditions of canal system drainage, irrigation and other high water levels are effectively solved. The oncomelania blocking walls are reasonable in design and simple in structure, are flexible to install and convenient for getting materials, completely meet the requirements of preventing and controlling oncomelania spreading in a shistosoma affected area, and have a good popularization prospect.

The invention relates to a shearing machine, in particular to an oncomelania tail shearing machine. The technical aim is to provide the oncomelania tail shearing machine which can realize automatic feeding and discharging, and can fix oncomelania. According to the technical scheme, the oncomelania tail shearing machine comprises a base, supporting columns arranged on the base, a transmission mechanism connected between the tops of the supporting columns, and a feeding mechanism connected to the transmission mechanism. Through cooperation of the transmission mechanism and the feeding mechanism,the effects of carrying out feeding and conveying at the same time and finally cutting the oncomelania can be achieved, the operation is easy, and the working efficiency of people is improved; and through cooperation of a discharging mechanism and a screening mechanism, in the cutting process, the oncomelania can be fixed and the cut oncomelania is pushed out; and in a shaking process, impuritiescan be shaken off, so that people can collect the impurities conveniently.

The invention discloses a pesticide composition with emamectin benzoate and niclosamide ethanolamine, and belongs to the field of chemical prevention. The pesticide composition comprises the niclosamide ethanolamine, the emamectin benzoate and auxiliaries. The niclosamide ethanolamine and the emamectin benzoate are effective ingredients. The pesticide composition has the advantages that excellent synergistic effects can be realized by the pesticide composition for preventing soft injurious insects and oncomelania in particular; a synergistic ratio of the pesticide composition to the oncomelania during indoor bioassay is 20:1-1:20; the obvious synergistic effects and good prevention effects can be realized by the pesticide composition, the pesticide composition is low in dosage and safe for environments and target biomasses, can be used for various insect pests and also can be used for treating other soft insect pests (such as pomacea canaliculata and slug), excellent effects for relieving pesticide resistance of the oncomelania can be realized.

A component 22-imino-3-[4'-(6-deoxy-alpha-L-mannoside)-beta-D- glucoside]-5-dehydrospirostan is prepared from the fruit of a plant 'Huangguoqie' through extracting in organic solvent, chromatography of silica gel column, and HPLCseparation. It has the activity to kill oncomelania.

The invention relates to a medicament used for killing oncomelania and schistosoma japonicum cercaria, in particular to an environmental-protection typed niclosamide slow releasing block and a preparation method thereof. The best proportioning of the slow releasing block of the invention according to the weight portions is 50 portions of niclosamide ethanolamine salt wettable powder, 30 portions of sawdust, 20 portions of perlite and 3 portions of polyvinyl alcohol for the upper floating type and is 50 portions of niclosamide ethanolamine salt wettable powder, 20 portions of sawdust, 30 portions of red soil and 3 portions of polyvinyl alcohol. The invention uses the niclosamide recommended by WHO as the main medicament; the adopted carrier material is sawdust which has low price and causes no environmental pollution; more than 6,000m<2> can be released in the operation of two persons each day, thus saving the niclosamide by 50% and the cost by 40%.

A method for controlling the oncomelania by using the tea-oil tree's seed cake includes such steps as pulverizing by 20 meshes, and proportionally applying directly or after immersed for 4-10 hr.

The invention discloses a method for killing oncomelania and lymnaeidae in a pond, which comprises the following steps of: diluting niclosamide by using water, and uniformly splashing in the whole pond 10 to 15 days before seeds enter the pond to make the final concentration of pond water be 0.30 to 0.50 g / m<3>, and keeping liquid medicine concentration for 24 to 48 hours to effectively kill gastropods such as the oncomelania, the lymnaeidae and the like, gastropod eggs, rough fish, parasites and the like. The consumption is appropriately increased when the temperature is lower than 20 DEG C. The method of the invention is simple, convenient to operate, has high speed, no residues, small consumption and low cost, and is safe to shrimps and crabs.

The invention discloses a preparation method of a crab breeding special disinfectant, and belongs to the technical field of aquatic disinfectant preparation. The preparation method comprises the steps: drying croton seed under the blazing sun, preparing bean meal by an oil press, then mixing with vinasse and the like, supplementing with protease and lipase, inoculating with probiotics, fermenting, then allowing tea leaves to stand for getting moldy, carrying out high pressure steaming, grinding into a slurry, and mixing with the croton seed meal fermented material, a filling powder and the like to prepare the crab breeding special disinfectant. The product prepared by fermenting the croton seed meal by the probiotics effectively kills intermediate hosts, such as oncomelania, escargots and the like, of parasites in a pond, and cooperates with the tea leaf slurry to achieve the purpose of removing animal worm eggs, spores and harmful bacteria; after the disinfectant is used, the disinfectant can be degraded by soil microorganisms, is used as nutrients absorbed by aquatic animals and plants, and effectively solves the problem of drug residues of traditional crab breeding disinfectants.

The invention relates to application of beta-resorcylic acid large ring lactone expressed through the following general formula (1) in the specification to controlling harmful snails. An indoor molluscicidal drug soaking activity evaluation test indicates that four compounds expressed through the general formula (1) have good molluscicidal activities, wherein when the four compounds are used under the concentration of 10 mg / L for 72 hours, Monocillin II can achieve the molluscicidal rate of more than 95 percent on oncomelania and the molluscicidal rate of more than 70 percent on ampullaria gigas; Radicicol can achieve the molluscicidal rate of more than 75 percent on the oncomelania and the eradicative rate of more than 90 percent on the ampullaria gigas; Monocillin I can achieve the molluscicidal rate of more than 40 percent on the ampullaria gigas; and Monocillin III can achieve the molluscicidal rate of more than 70 percent on the ampullaria gigas.

The invention relates to an application of Hypothemycin disclosed in a formula (1) in preventing and treating harmful spiral shells. An indoor dipping spiral shell killing chemical activity evaluation test proves that the compound has good activity on killing the spiral shells. The chemical is applied for 72 hours under the concentration of 10mg / L, the killing rate on the oncomelania is above 90%, and the killing rate on Ampullariidae is 100%.

The invention relates to a snail-killing agent of total alkaloid granules in leonurus for perishing Oncomelania and a preparation technique and application method thereof. Fresh whole plant of the leonurus before the stage of full bloom is ground with appropriate amount of water and squeezed into liquor, then centrifugally separated or filtered; and dregs are aqueous-extracted and are filtered for residue removal; supernatant and filtered fluid are decompressed and concentrated to the specific gravity of 1.10 to 1.15, and absorbed by 732 cation exchange resin, then eluted by HCL with the concentration of 5 percent, decolorized and eluted by ethanol with the concentration of 95 percent, decompressed and dried to obtain the dried product of the total alkaloid in leonurus. Aqueous solution with the concentration of 0.60g / L to 1.0g / L prepared by the total alkaloid has obvious snail-killing effect; when the aqueous solution with the concentration of 0.60g / L is used for treating the Oncomelania for 4 to 5 days, the poisoning effect can reach 100 percent. The agent can be added into baits such as sugar powder and flour and then made into granules (the ratio of the total alkaloid in leonurus: the sugar powder: the flour: acacia equals to 1:5:40:5); the granules are bestrewed for 100g per hectare, the mortality of the Oncomelania can reach 100 percent after 3 days. The snail-killing agent of the invention has simple preparation technique, relatively low cost, convenient for storing, transporting and no pollution to the environment and no toxicity to human beings, livestock and fishes.

The invention discloses a biopesticide oncomelania killing drug which is composed of the following raw materials in percentage by weight: 4% of metaldehyde powder, 12-20% of oil-tea-cake powder, 8% of gypsum powder, 1% of an attractant and 73-78% of flour. According to the biopesticide oncomelania killing drug disclosed by the invention, tea saponin is compounded with metaldehyde, the usage amount of the metaldehyde is reduced from 6% to 4%, the content of the metaldehyde in the pesticide is effectively reduced, and the field dosage is reduced; the problem that diseases even cancers are possibly caused due to long-term contact with the pesticide, and genetic mechanisms of living organisms are possibly injured in severe cases so as to cause gene mutation can be solved. The potential hazard of the metaldehyde on the environment and human bodies can be reduced; and the drug effect is obvious, and the dosage cost is reduced.