Oncomelania killing medicine of niclosamide ethanolamine particle preparation and preparation method thereof

A technology of spirulina ethanolamine salt and granules, which is applied in the field of oncomelania drug preparations, can solve the problems of lack of availability of molluscicides and difficulty in using drugs to kill snails, and achieve the effect of increasing the effect of killing snails, reducing the cost of medication, and being easy to use Effect

Inactive Publication Date: 2012-01-25
JIANGSU ESSENCE AGROCHEM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to provide a kind of snail snail amine ethanolamine salt granules, which is suitable for killing snails in the environment where snails grow and are relatively dry and water-deficient, so as to solv

Method used

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  • Oncomelania killing medicine of niclosamide ethanolamine particle preparation and preparation method thereof
  • Oncomelania killing medicine of niclosamide ethanolamine particle preparation and preparation method thereof
  • Oncomelania killing medicine of niclosamide ethanolamine particle preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Embodiment 1: the preparation of spiroxamine ethanolamine salt granule

[0014] In terms of mass percentage, 1% spiroxamine ethanolamine salt, 0.1% sodium lauryl sulfate, and 0.5% alkylphenol polyoxyethylene ether formaldehyde polycondensate sulfate are mixed and pulverized by a jet mill to obtain powder; Mix evenly with 98.3% quartz sand and 0.05% (based on polyvinyl alcohol content) polyvinyl alcohol aqueous solution (mass concentration is 1%, the same below), and dry to obtain spiroxamin ethanolamine salt granules.

Embodiment 2

[0015] Embodiment 2: the preparation of spiroxamine ethanolamine salt granules

[0016] In terms of mass percentage, 5% spiroxamine ethanolamine salt, 0.2% sodium lauryl sulfate, and 1% alkylphenol polyoxyethylene ether sulfonate are mixed and pulverized by a jet mill to obtain powder; 93.7% quartz sand and 0.1% (based on polyvinyl alcohol content) polyvinyl alcohol aqueous solution are uniformly mixed and dried to obtain spiroxamin ethanolamine salt granules.

Embodiment 3

[0017] Embodiment 3: the preparation of spiroxamine ethanolamine salt granules

[0018] In terms of mass percentage, 10% spiroxamine ethanolamine salt, 0.5% Geropon L-WET / P, 1.5% alkylphenol polyoxyethylene ether formaldehyde polycondensate sulfate, after mixing, pulverize through a jet mill to obtain powder; Mix evenly with 87.8% quartz sand and 0.1% (based on polyvinyl alcohol content) polyvinyl alcohol aqueous solution, and dry to obtain spiroxamate ethanolamine salt granules.

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Abstract

The invention discloses oncomelania killing medicine of a niclosamide ethanolamine particle preparation and a preparation method thereof. The particle preparation consists of the following ingredients in percentage by mass: 1 percent to 20 percent of niclosamide ethanolamine, 0.1 percent to 2.0 percent of wetting agents, 0.1 percent to 3.0 percent of dispersing agents, 0.01 percent to 0.2 percent of binding agents and the balance carriers. The oncomelania killing effect of the niclosamide ethanolamine is enhanced, the use is convenient, the pollution is reduced, and the particle preparation is favorable for laying the foundation for further controlling the schistosomiasis during the oncomelania killing in dry and waterless marshland.

Description

technical field [0001] The invention relates to a snail-killing drug snailicide ethanolamine salt granule and a preparation method thereof, specifically belonging to the technical field of snail-killing drug preparations. Background technique [0002] Spirulina is the only molluscicide recommended by the World Health Organization for on-site use in my country. It is usually made into 50% spirulina ethanolamine salt wettable powder, 26% tetramer·spirulina suspension concentrate, 70% spirulina Use of spirulina wettable powder and 25% spirulina emulsifiable concentrate. However, these preparations need to be mixed with water when applied, and their application is limited in the dry and water-deficient environment where snails grow on the islands of rivers and lakes. Although they can be made into powders and sprayed directly, they are likely to cause dust drift and pollution. environment, and it is easy to cause drug harm to users. Contents of the invention [0003] The purp...

Claims

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Application Information

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IPC IPC(8): A01N37/40A01N25/12A01N65/08A01P9/00
CPCY02A50/30
Inventor 戴焰林梁晓天戴建荣
Owner JIANGSU ESSENCE AGROCHEM
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