Composition of medication for treating ulcer in the oral cavity, and preparation method

A technology for oral ulcers and compositions, applied in the field of pharmacy, can solve the problems of disordered oral flora, large side effects, fungal infection, etc., and achieve the effects of alleviating pain, significant curative effect, and reducing irritation.

Active Publication Date: 2006-12-06
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] According to this, Western medicine often uses hormones, antibiotics, etc. for treatment, but long-term use may also cause the disorder of the flora in the oral cavity, and then cause fungal infection or drug resistance, the curative effect is not very satisfactory, and the side effects are relatively large. The comprehensive treatment characteristics of multi-directional, multi-target, and low side effects are increasingly recognized by more and more people

Method used

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  • Composition of medication for treating ulcer in the oral cavity, and preparation method
  • Composition of medication for treating ulcer in the oral cavity, and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Example 1. A kind of pharmaceutical composition for the treatment of oral ulcer, it is the medicament (unit: gram) that it is made of the raw material of following weight ratio,

[0028] Wine Propolis 4 Gardenia 15 Dandelion 15

[0029] Ophiopogon japonicus 10 Catechin 2 Dracaena 1.

[0030] The pharmaceutical dosage form of this embodiment is buccal tablet, and its preparation method adopts the conventional preparation process of traditional Chinese medicine buccal tablet in the prior art.

Embodiment 2

[0031] Example 2. A preparation method of a pharmaceutical composition for the treatment of oral ulcer, the steps are as follows,

[0032] (1) Take 3 flavors of Gardenia, Ophiopogon japonicus and Dandelion, add water to decoct 3 times, combine the water extracts, concentrate under reduced pressure at 0.06MPa70°C, until the density is 1.20g / ml when measured at 50°C, the concentrated solution Add ethanol until the alcohol content is 70%, let it stand for 12 hours, take the supernatant to recover ethanol, and spray dry to obtain dry extract powder A;

[0033] (2) Soak the propolis with 10 times the amount of 95% ethanol for 24 hours, filter, concentrate the filtrate and dry it at low temperature to obtain wine-made propolis, and pulverize it to obtain extract powder B;

[0034] (3) The catechu is made into coarse powder, soaked in 10 times the amount of water for 12 hours, filtered, the filtrate is concentrated and dried under reduced pressure to obtain dry extract powder C; or ...

Embodiment 3

[0036] Example 3. A preparation method of a pharmaceutical composition for the treatment of oral ulcer, the steps are as follows,

[0037] (1) Take 3 flavors of Gardenia, Ophiopogon japonicus and Dandelion, add water to decoct 3 times, combine the water extracts, concentrate under reduced pressure at 0.06MPa70°C, until the density is 1.20g / ml when measured at 50°C, the concentrated solution Add ethanol until the alcohol content is 70%, let it stand for 12 hours, take the supernatant to recover ethanol, and spray dry to obtain dry extract powder A;

[0038] (2) Soak the propolis with 10 times the amount of 95% ethanol for 24 hours, filter, concentrate the filtrate and dry it at low temperature to obtain wine-made propolis, and pulverize it to obtain extract powder B;

[0039] (3) The catechu is made into coarse powder, soaked in 10 times the amount of water for 12 hours, filtered, the filtrate is concentrated and dried under reduced pressure to obtain dry extract powder C; or ...

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PUM

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Abstract

A medicinal composition for treating oral ulcer is prepared from the wine-treated propolis, capejasmine fruit, dandelion herb, ophiopogon root, catechu and Dragon's blood. Its preparing process is also disclosed.

Description

technical field [0001] The invention provides a medicament made from traditional Chinese medicines, in particular a pharmaceutical composition for treating oral ulcers, and also relates to a preparation method of the pharmaceutical composition. Background technique [0002] Recurrent aphthous ulcer, also known as recurrent oral ulceration, or recurrent aphthous ulcer, RAU for short, is one of the most common oral mucosal diseases, and is the highest incidence in mucosal diseases. Clinically, according to the size, number and depth of ulcer performance at the time of onset, it can be divided into three types: mild aphth, stomatitis type aphth and periglandular aphtha. Scholars at home and abroad have done a lot of research on its etiology. The etiology is not yet fully understood. It is believed to be related to immune abnormalities, psychosocial factors, heredity, infection, and nutritional deficiencies. , diarrhea, constipation, gastric ulcer, etc., may...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P1/02A61K35/64A61K35/644
Inventor 丁岗李明慧曹亮朱华荣沈爱琴沈鸣
Owner JIANGSU KANION PHARMA CO LTD
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