A low frequency/small Power focusing ultrasonic therapeutic apparatus

Abstract

The invention comprises ultrasonic transducer, low-frequency power source, and the control circuit described above is connected ultrasonic transducer, the described ultrasonic transducer includes a sound head, which was set side of a focusing concave mirror. Through the focusing concave mirror, the low-frequency ultrasonic generated by ultrasonic transducer focuses and biological effects generated in focal area was restricted to certain position, not only focus the ultrasonic beam (targeted), reduce the required energy by two energy level change of one factor and the use of combinative micro vesicle, thus reduce injury risk of brain tissue, but also provides us a non-invasive, targeted thrombolytic, blood-brain barrier (BBB) opening and gene transfection of nerve cells therapy device, especially as a barrier to the blood-brain transmission of drugs and macromolecular in the central nervous system, and an important mean to enter the brain tissue.

Description

technical field [0001] The invention relates to a disease treatment device, in particular to a low-frequency and low-power focused ultrasonic treatment instrument. technical background [0002] Ultrasound technology has been applied to the medical field for nearly half a century, and is mainly used in the clinical diagnosis of heart, kidney, liver and other chest and abdominal distension organs. However, the application of ultrasound technology in the research of diseases of the central nervous system, such as the research on the treatment of brain tumors and cerebrovascular diseases, is rare, and only in recent years have some breakthroughs. In addition to the low transmittance and high impedance of ultrasound penetrating the skull, the key issue is also related to the damaging effect of high-energy ultrasound on brain tissue. Therefore, it has always been the bottleneck of high-energy focused ultrasound (HIFU) non-invasive treatment of intracranial diseases. In recent yea...

AI Technical Summary

Problems solved by technology

Although a large number of in vitro and animal experiments have shown that HIFU can better promote the dissolution of fibrin and provide a promising new therapy for clinical application, the application of high-frequency ultrasound in intracranial diseases is greatly limited. , the biggest obstacle is the absorption and impedance of the skull to sound waves, and the transmittance of HIFU through the skull is very limited, which limits its application in cerebrovascular diseases

On the other hand, animal experiments using HIFU found that it is easy to cause brain tissue damage, and cause platelet aggregation and fibrin deposition, resulting in vascular occlusion

Therefore, there is no real ultrasonic treatment instrument for central nervous system diseases at home and abroad.

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