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Specific effervescent tablet against candida albicans IgY

A technology of Candida albicans and effervescent tablets, applied in the direction of antifungal agents, antibodies, diseases, etc., can solve problems such as increased adhesion activity, unsalable products, and damp sanitary napkins, so as to reduce drug toxicity and side effects and make the drug effective Rapid, good antibacterial effect

Inactive Publication Date: 2007-06-20
杜木根
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to reports, among all vulvovaginal inflammations in the United States, the incidence rate of vulvovaginal candidiasis (VVC) is the highest, about 39%, and the main pathogenic bacteria is Candida albicans, accounting for more than 85%-90%, about 3 / 4 Women of childbearing age have suffered from VVC at least once, of which 16% have one attack, 84% have a second attack, and 35% have a second attack for more than six times. The increase in the sugar content of the mucous membrane provides sufficient carbon sources for the growth and budding of Candida. A more complex mechanism may be that estrogen increases the adhesion activity of vaginal epithelial cells to Candida and promotes the formation of yeast hyphae; 2. Contraceptives : The application of oral contraceptives containing high estrogen can increase the vaginal colonization rate of Candida, and the mechanism is the same as pregnancy; 3. Diabetes; 4. Simultaneous application of multiple broad-spectrum antibiotics can lead to flora imbalance, decreased immunity, and infection
5. Other factors: women's sanitary napkins are widely used, and the current sanitary napkin manufacturers gather, and the products are unsalable. In addition, buyers often buy large quantities for long-term storage for convenience and economy, resulting in moisture in sanitary napkins and even the outer packaging. damaged

Method used

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Embodiment Construction

[0030] Specific anti-Candida albicans IgY (antibody titer > 1:2600) 10mg

[0031] Boric acid 60mg

[0032] Sodium bicarbonate 50mg

[0033] Starch 30mg

[0034] Microcrystalline Cellulose 130mg

[0035] Sodium Lauryl Sulfate 3mg

[0036] Talc powder 30mg

[0037] Preparation method: Weigh 500 mg of specific anti-Candida albicans IgY (antibody titer > 1:2600), 3000 mg of boric acid, 2500 mg of sodium bicarbonate, 1500 mg of starch, 6.5 g of microcrystalline cellulose, 150 mg of sodium lauryl sulfate, Talc powder 1500mg, ground into powder and sieved separately. Part of the starch is mixed with boric acid and sodium bicarbonate respectively, and finally mixed with the main drug and other auxiliary materials, and directly compressed into tablets to obtain 50 tablets in total.

[0038] The specific anti-Candida albicans IgY effervescent tablet vaginal deep administration 1 tablet / day that above-mentioned embodiment is obtained, consecutive five days is a small course of trea...

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Abstract

A vaginal IgY effervescent tablet specifically to kill Candida albicans for treating mycotic vaginitis of woman, even if gravida and puerpera, is disclosed.

Description

technical field [0001] The invention relates to the application of a biological preparation belonging to chicken yolk immunoglobulin (IgG, IgY) products, in particular to specific anti-Candida albicans IgY effervescent tablets. Background technique [0002] In the past ten years, the research and application of IgY has been a hot topic and a very active topic in the field of immunology. Since the discovery of IgY by Williams (1962) abroad, the IgY that has been successfully prepared includes: anti-rotavirus IgY, anti-influenza virus IgY, anti-respiratory syncytial virus IgY, anti-Echinococcus granulosus IgY, anti-RNA polymerization Enzyme IgY, anti-human IgG IgY, anti-prostaglandin IgY, anti-thyroid hormone IgY, anti-insulin receptor IgY, anti-snake venom IgY, anti-scorpion venom IgY, etc. Although this domestic research started relatively late, anti-rotavirus IgY, anti-poliovirus IgY, anti-gastric cancer cell IgY, anti-HPIgY, anti-caries IgY, etc. have been prepared, and t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/395A61K9/20A61K9/46A61P15/02A61P31/10
Inventor 傅颖媛
Owner 杜木根
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