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Medicine for hyperlipemia and its production process

A drug and a technology of action, applied in the field of drugs for hyperlipidemia and the production process thereof, can solve problems such as difficulty in satisfying patients, and achieve the effects of low manufacturing cost, simple production process and safe clinical application

Active Publication Date: 2007-06-27
JUMPCAN PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although such drugs have better therapeutic effects, it is still difficult to meet the needs of the majority of patients, and it is necessary to continue to work hard to develop better new Chinese medicines.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Radix Paeoniae Rubra 550g, Salvia miltiorrhiza 550g, Polygonum multiflorum 450g, Hawthorn 450g

[0040]Add dandelion to 70% ethanol, reflux and extract twice, each time the amount of solvent is 6 times, each time for 1 hour, filter, combine the filtrates, recover the ethanol to obtain the medicinal liquid A1; times, each water consumption is 4 times, the first time 1.5 hours, the second time 1 hour, filter, decoct and merge to obtain medicinal liquid B1; Radix Paeoniae Rubra adds 50% ethanol, reflux extracts twice, each time solvent amount is 6 times, 1 hour each time, filter, combine the filtrates, and recover the ethanol to obtain the medicinal solution C1.

[0041] Combine the above three medicinal solutions A1, B1 and C1, and concentrate under reduced pressure (60-70°C) until the relative density of the extract is 1.2-1.25 (60°C).

Embodiment 2

[0043] Radix Paeoniae Rubra 110g, Salvia miltiorrhiza 110g, Polygonum multiflorum 90g, Hawthorn 90g

[0044] Radix ginseng was extracted twice with 90% ethanol by reflux, each time the amount of solvent was 4 times, the first time was 2 hours, the second time was 1 hour, filtered, the filtrates were combined, and the medicinal liquid A2 was obtained after recovering the ethanol; the filter residue and the Polygonum multiflorum , hawthorn, decoct twice with water, each time with 6 times the water consumption, 1.5 hours each time, filter, and combine the decoctions to obtain medicinal solution B2; add 60% ethanol to Radix Paeoniae Rubra, reflux extraction twice, the first solvent The volume is 8 times, and the time is 1.5 hours. The second solvent volume is 5 times, and the time is 1 hour. Filter, combine the filtrates, and recover the ethanol to obtain the drug solution C2.

[0045] Combine the above three liquid medicines A2, B2 and C2, concentrate under reduced pressure (60-7...

Embodiment 3

[0046] Embodiment 3: the preparation of capsule

[0047] The extract obtained in Example 1 was dried under reduced pressure (at a temperature of 50-55°C), and the vacuum degree was less than -0.08Mpa to obtain a dry extract. The dried extract is pulverized and passed through a No. 5 sieve to obtain a medicinal powder, which is packed into capsules and made into 1000 capsules.

[0048] The medicinal powder obtained above is brown in color; slightly gas, slightly bitter and slightly sour. The fixed funnel method was used to measure the angle of repose. As a result, the measured values ​​of the angle of repose ranged from 32.97° to 37.25°, which were all less than 45°. The results show that the fluidity of the powder is better.

[0049] The drug capsules prepared above have been proved by stability studies that the stability meets the requirements.

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Abstract

The present invention relates to medicine, and is especially one kind of blood fat reducing Chinese medicine capsule prepared with red peony root, red sage, prepared fleeceflower root, and haw in the weight ratio of 1-1.5 to 1-1.5 to 1 to 1. The Chinese medicine capsule is used in preventing and treating hyperlipemia, atherosclerosis and other diseases. The Chinese medicine capsule possesses the functions of promoting blood circulation to disperse blood clots and reducing blood fat.

Description

technical field [0001] The invention relates to a medicine with blood lipid-lowering effect and a preparation method thereof, in particular to a traditional Chinese medicine capsule with blood fat-lowering effect, and the medicine can prevent or treat diseases such as hyperlipidemia and atherosclerosis. It belongs to the field of medicine. Background technique [0002] Hyperlipidemia is the primary pathogenic factor of atherosclerosis, which is directly related to the occurrence of cardiovascular and cerebrovascular diseases. The disease is more common in middle-aged and elderly people over the age of 40, and develops rapidly after the age of 49, with more men than women and more mental workers. Cholesterol and triglycerides can increase with age, and reach the peak at the age of 60 for men and 70 for women. In recent years in my country, with the improvement of living standards and the change of diet structure, the incidence of hyperlipidemia is also increasing year by ye...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/734A61K9/48A61P3/06A61P9/10
Inventor 曹龙祥李昌龙田刚
Owner JUMPCAN PHARMA GRP
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