Method for analyzing a glycomolecule

a glycomolecule and structure technology, applied in the field of structure analysis of glycomolecules, can solve problems such as difficult analysis, and achieve the effect of facilitating access to glycomolecules and simplifying sample preparation and processing
US20050186645A1Inactive Publication Date: 2005-08-25PROCOGNIA ISRAEL
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
PROCOGNIA ISRAEL
Publication Date
2005-08-25
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates generally the structural analysis of glycomolecule-containing macromolecules, such as those that occur either attached to proteins (proteoglycans, glycoproteins), lipids, or as free saccharides.
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Description

RELATED APPLICATIONS

[0001] This application claims the benefit of, and priority to, U.S. Ser. No. 60 / 531,578, filed Dec. 18, 2003. The contents of this application are incorporated herein by reference in their entirety.FIELD OF THE INVENTION

[0002] The invention relates generally to the structural analysis of glycomolecules, which are molecules that contain carbohydrates and include carbohydrates attached to proteins (proteoglycans, glycoproteins), to lipids, or carbohydrates present as free polysaccharides. BACKGROUND OF THE INVENTION

[0003] Mammalian glycoprotein oligosaccharides are commonly built from a limited number of monosaccharides. Nevertheless, structural diversity is vast, mainly due to complex branching patterns. Glycosylation sites on glycoproteins commonly display microheterogeneity in that they can be fully or partially occupied by structurally diverse oligosaccharides. Consequently, a glycoprotein is not typically isolated as a single structural entity, but rather ...

Claims

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