Composition for treating skin pigmentation
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Benefits of technology
Problems solved by technology
Method used
Image
Examples
example 1
Extraction of Arils of Strelitzia nicolai (Extract Concentrate)
[0039]A 1% aril solution was created by homogenizing 3 g of Strelitzia nicolai in 297 mL, pH 7.0 water in an ice bath using a Silverson L4R homogenizer (Chesham Bucks, England) at a speed of 4000 rpm for 10 minutes. The solution was further homogenized using a Niro Panda 2K (Bedford, N.H., USA) by passing the solution four times through the Niro homogenizer at 1000 bar pressure. After homogenization, the pH was brought up to 7.0 using a 0.1% NaOH solution.
[0040]The homogenized solution was filtered sequentially through four Whatman filters: #41, #2, #6, and #5, respectively, which correspond to 25 μm, 8 μm, 3 μm, and 2.5 μm. Finally, the solution was filtered through a 0.2 μm Nalgene filter. The solution was then concentrated to remove water in order to achieve a final NVM of Strelitzia nicolai aril extract concentrate having approximately 13% extract concentrate solids.
example 2
Bilirubin Degrading Ability of Strelitzia nicolai Aril Extract
[0041]For high pressure liquid chromatography (HPLC) analysis, a control of 0.050% bilirubin (Frontier Scientific, Logan, Utah) in pH 7.0 water was run along with samples of the Strelitzia nicolai aril extract concentrate of Example 1. The aril extract was diluted with pH 7.0 water to give a final concentration of 0.1%, 0.5% or 0.95% Strelitzia nicolai aril extract along with a 0.050% concentration of bilirubin in each solution.
[0042]HPLC solutions were prepared as described in Spivak and Yuey, Biochem. J. (1986) 234 (101-109), which is incorporated by reference herein. For HPLC solvent A, 0.04 M sodium acetate in methanol was prepared by dissolving 3.282 g sodium acetate from Sigma Chemical Co (St. Louis, Mo., USA) in 1000 mL methanol from Fisher Scientific (Pittsburgh, Pa., USA). For solvent B, 1% ammonium acetate in water was prepared by adding 10 ml of glacial acetic acid from Fisher Scientific to 990 ml of distilled ...
example 3
Preparation of Strelitzia nicolai Aril Extract in Oil-in-Water Emulsions
[0046]The Strelitzia nicolai aril extract from Example 1 was formulated into an oil-in-water emulsion using the following formulation and process:
IngredientINCI Nomenclature%Phase (A)WaterWaterQ.s to 100Versene ™ 100Tetrasodium EDTA0.10GlycerinGlycerin2.00Carbopol ® Ultrez 10Carbomer0.20Phase (B)Brookswax ™ DCetearyl Alcohol and Ceteareth-202.00Liquiwax DIADD**DioctyldodecylDodecanedioate5.00Loronate TMP-TCTrimethylolpropaneTricaprylate / 2.00TricaprateArlacel ™ 60Sorbitan Stearate1.50Stearyl AlcoholStearyl alcohol0.20Cetyl AlcoholCetyl Alcohol0.50Stearic AcidStearic Acid0.50Myritol ® 318Caprylic / Capric Triglyceride2.00DC 200 / 100 cSTDimethicone0.75Phase (C)WaterWater5.00TEA 99Triethanolamine0.25Phase (D)Extract Example 1—1.00Mikrokill ® COSPhenoxyethanol, Caprylyl Glycol,0.75and ChlorphenesinProcedure:1. Combine Phase A and heat to 75° C. Mix until uniform.2. Combine Phase B and heat to 75° C. Mix until uniform.3....
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com