Method for separating estrogen from placenta

Abstract

The present invention provides a method of separating estrogen from placenta, which uses supercritical fluid technique to load the placenta powder of human body or sheep, pig, deer and other animals into an extraction tank. Under the operating conditions of preset pressure and temperature, supercritical solvent is added into the extraction tank to extract estrogen from placenta, so as to acquire de-estrogen placenta powder and placenta extract liquor. Under the same condition, the de-estrogen placenta extract liquor and supercritical solvent are added by a preset volume flow ratio into an adsorption tank. The estrogen in the placenta extract liquor is adsorbed by the adsorption tank to obtain de-estrogen placenta extract. It is then eluted with ethanol solution by gradient proportion to obtain purified natural estrogen.

Description

[0001]The current application claims a foreign priority to the patent application of Taiwan No. 103112021 filed on Mar. 31, 2014.BACKGROUND OF INVENTION[0002]1. Field of the Invention[0003]The present invention relates generally to a technology of separating estrogen from placenta, and more particularly to a method which can not only reduce or remove estrogen from placenta, but also deodorize, remove bitterness, enhance the taste, and ensure food safety.[0004]2. Description of Related Art[0005]Placenta contains a wide range of bioactive ingredients, and may produce almost all substances that can be found in any human organ to support the growth and development of the fetus in the mother's womb. This biochemical treasure supplies substances to the growing fetus that cannot be generated by itself. Placenta also contains a variety of enzymes that support the metabolism of steroid hormones, such as estrogen and progesterone. Placenta can also adjust the body's functional state, enhance ...

AI Technical Summary

Benefits of technology

The present invention provides a method to separate estrogen from placenta using a safe and nontoxic supercritical solvent. This method involves physical extraction at high pressure / low temperature and separation at low pressure / low temperature without the need for complicated solvent removal, concentration, and separation procedures. The supercritical solvent is recyclable, making the method environmentally-friendly, safe, and practical.

Problems solved by technology

However, the hormone replacement therapy has been stopped recently in the U.S. because research shows that long-term hormone supplementation may cause cancer.

The damage of acid and alkali on effective functional ingredients and enzyme activity should be taken into consideration, thus, mass production is infeasible.

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