Compositions for Improved Body Composition

a body composition and composition technology, applied in the field of dietary supplements, can solve the problems of undesirable loss of lean mass, increase of fat mass, etc., and achieve the effects of reducing fat, reducing weight, and reducing weight gain

Inactive Publication Date: 2015-12-17
NORTHERN INNOVATIONS HLDG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0007]According to another embodiment, there is provided a method of reducing weight or reducing weight gain in an individual, the method comprising administering a composition comprising alpha-lipoic acid and curcumin.
[0008]According to another embodiment, there is provided a method of reducing fat or reducing fat gain in an individual, the method comprising administering a composition comprising alpha-lipoic acid and curcumin.
[0009]According to another embodiment, there is provided a method of maintaining lean mass or reducing loss of lean mass in an individual, the method comprising administering a composition comprising alpha-lipoic acid and curcumin.
[0010]According to another embodiment, there is provided a method of maintaining appetite, increasing appetite, or reducing loss of appetite in an individual, the method comprising administering a composition comprising alpha-lipoic acid and curcumin.
[0011]According to another embodiment, there is provided a method of improving the characteristics of a nutritional supplement, the method comprising adding to said nutritional supplement a composition comprising alpha-lipoic acid and curcumin prior to ingestion of said nutritional supplement.

Problems solved by technology

In order to gain lean mass, or muscle, it is generally acknowledged that an excess of calories must be consumed above those expended—however, this often results in increases in fat mass as well.
Alternatively, in order to lose weight, most of which is preferably fat, it is necessary to consume a deficit of calories—however, this often results in an undesirable loss of lean mass.
Most known dietary supplements benefit changes in body composition to a limited degree and / or at the cost of an accompanied unwanted change in body composition.

Method used

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  • Compositions for Improved Body Composition
  • Compositions for Improved Body Composition
  • Compositions for Improved Body Composition

Examples

Experimental program
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Effect test

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Method

[0038]Based on the preferred dose in humans of about 13.33 mg / kg / day or about 800 mg per day for a 60 kg individual for alpha-lipoic acid and the preferred dose in humans of about 5 mg / kg / day or about 300 mg per day for a 60 kg individual for curcumin, diets for the mice were designed to provide the mice with the appropriate equivalent amounts of the required components for each of the experimental groups. The following formula for Human Equivalent Dose (HED) was used to calculate the dose for mouse diets:

HED=Animal Dose×(Animal Weight / Human Weight)0.33 [0039]for alpha-lipoic acid,

800 mg / kg=Animal Dose×(0.025 kg / 60 kg)0.33

13.33 mg / kg=Animal Dose×(0.0766)[0040]Animal Dose=174.02 mg / kg[0041]and for curcumin,

300 mg / kg=Animal Dose×(0.025 kg / 60 kg)0.33

5 mg / kg=Animal Dose×(0.0766)[0042]Animal Dose=65.27 mg / kg

[0043]5 week old C57BL6 / J male mice were divided into 2 groups as follows: normal diet (ND) (10% kcal / fat) or high fat diet (HFD) (60% kcal / fat) each containing the same total c...

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Abstract

A nutritional supplement is provided comprising alpha-lipoic acid and curcumin. The nutritional supplement may be used for reducing weight or reducing weight gain, for reducing fat or reducing fat gain, for reducing loss in lean mass or maintaining lean mass, or for reducing loss of appetite or for maintaining appetite.

Description

FIELD OF THE INVENTION[0001]The present application claims priority from non-provisional patent application Ser. No. 14 / 178,272, filed on Feb. 12, 2014.[0002]The present invention relates generally to dietary supplements. Particularly, the present invention provides compositions comprising alpha-lipoic acid and curcumin and methods of using the compositions.BACKGROUND OF THE INVENTION[0003]The use of dietary supplements among individuals, including recreational and elite athletes, as well as sedentary individuals wishing to improve health parameters, has become increasingly popular due to studies suggesting efficacy. While there are many dietary supplements for diverse indications ranging from general health improvement (e.g. vitamins and minerals) to athletic performance improvement (e.g. creatine and beta-alanine), a large number of dietary supplements are taken for the purpose of improving body composition.[0004]Depending on the goal of the individual, dietary supplements may be ...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K31/385A61K31/12
CPCA61K31/12A61K31/385A23L33/10A23L33/30A23V2002/00
Inventor BAGCHI, DEBASISDOHERTY, JOHNAPONG, PHILIPJOSHI, VAISHALIPETERS, JASON
Owner NORTHERN INNOVATIONS HLDG
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