Analysis and screening of poly-functional secretion profiles
a poly-functional secretion and profile technology, applied in the field of cellular analysis, can solve problems such as significant challenges, and achieve the effects of high parallelization and scalable manner, improved detection accuracy, and sample throughpu
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[0050]Efforts to characterize the state or capabilities of a biological system or sample may be confounded or obscured by bulk analysis methods. This is evident in cellular analysis such as immunological surveys wherein a sample comprising many cells analyzed in a common volume or medium may act to mask or dilute analytes. It is therefore desirable in many instances to provide very small volume and single cell sample analysis capabilities. For small sample volumes including those involving a single or a few cells it is further desirable to sequester multiple samples in discrete reaction regions or areas so they may be subjected to parallel analysis. Such methods may require avoiding sample-to-sample cross-talk and contamination while providing the ability to subject the samples to uniform and discrete treatment. Collection of accurate and sensitive data in a scalable and multiplexed format with minimal user intervention is also important.
[0051]A particular example of a biochemical a...
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