Surface disinfectant with residual biocidal property

Pending Publication Date: 2021-05-13
MICROBAN PROD CO INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention is about a disinfectant that has a residual biocidal property. The disinfectant is made by mixing a polymer binder, such as an oxazoline homopolymer or an extended or modified version of it, with a biocidal compound. The disinfectant also contains a carrier. The patent text describes the structure of the oxazoline homopolymer, which has different groups that can be attached to it. The invention also mentions other features of the disinfectant formulation and methods of making, using, and applying it.

Problems solved by technology

While some are beneficial to humans and the environment, others may have significant negative consequences for contaminated articles as well as the persons, animals and ecological members coming in contact with them.
Such maladies typically are fungal or bacterial infections and can afflict the victim locally or systemically.
As a result, these facilities house abnormally highly concentrated populations of patients with weakened immune systems.
Their resistance to one or more biocidal agents makes such infections particularly dangerous.
Nosocomial infections further deal a serious blow to the volume, quality, and cost of healthcare provided by hospitals and other institutions.
These programs typically include frequent hand-washing and frequent disinfection of surfaces.
Despite implementation of programs to curb nosocomial infections, infections still occur at unacceptably high rates.
A main disadvantage associated with consumer disinfectants and sanitizers is that, while they can be effective at initially killing microbes, the surface is easily and quickly re-contaminated through contact, airborne microbes, and un-killed residual microbes before treatment.
While some of the disinfectants would continue to offer some control if simply left on the surface, this would result in a greasy or tacky residue that would be easily negated by casual contact with the surface.
Thus, there is a desire for a home care and household cleaner that kills microbes quickly on contact, then acts as a residual disinfectant but yet does not have this undesirable sticky or tacky effect.
The food service industry also faces outbreaks in contamination of pathogens in the workplace and spreading disease out to consumers.
Even though food manufacturers adopt vigorous hygiene plans and comply with tight government hygiene regulations, major outbreaks of microbes are still reported occasionally that causes serious illness among consumers.
Biofilms present a large problem for public health because of increased resistance of biofilm-associated organisms to antimicrobial agents and for the potential of biofilm borne organisms to cause infections.
Current disinfectants do not have the ability to kill biofilms or to seal or lock-in biofilms on surfaces to prevent cross-contamination events and to prevent out growth.
There are limited solutions for surface biofilm problems.
For example, there is a building body of evidence that surface biofilms pose a problem in the healthcare setting for the above mentioned reasons.
In addition, biofilms are a recognized problem of possible contamination within the food industry.

Method used

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  • Surface disinfectant with residual biocidal property
  • Surface disinfectant with residual biocidal property
  • Surface disinfectant with residual biocidal property

Examples

Experimental program
Comparison scheme
Effect test

examples

[0135]The following examples illustrate liquid formulations made in accordance with aspects of the present invention. The testing results on these formulations demonstrate the desired residual sanitizing or disinfecting performance once being applied onto surfaces and dried. Cleaning performance is also tested on those formulations that not only provide residual disinfecting benefit but also cleaning features.

[0136]Formulations were tested for residual efficacy using the EPA 01-1A protocol. Briefly, bacteria were added to a glass slide and allowed to dry on the surface. The formulation was then sprayed onto the surface and dried to form a transparent film. Once a film had formed, the glass slide was exposed to alternating wet and dry cycles using the Gardner wear tester as described in the protocol. In between each cycle the slide was re-inoculated with bacteria. After the appropriate number of wear and re-inoculations (48 passes and 11 re-inoculations for healthcare formulation and...

example — wipe

Example—Wipe formulation

[0155]Wipe formulations A-I were prepared and tested on various substrates.

[0156]In the tests for Formulations A-F, 8 grams of formulation was added to a 7″×8″, 100% PP, 34 gram per square meter substrate. The substrate, which was obtained from Rockline Industries, was a Kimberly Clark melt blown product. The results are shown in Table 12 below.

TABLE 12ABCDEF(wt %)(wt %)(wt %)(wt %)(wt %)(wt %)Aquazol 5001.501.501.500.600.901.20BTC 8850.450.901.431.001.001.00(50% Active)Tomadol 25-120.200.200.200.200.200.20Fragrance0.100.100.100.100.100.10WaterbalancebalancebalancebalancebalancebalanceLog2.4 3.9 4.7 2.8 3.2 Reduction*Result*FailPassPassFailFailPass*Clorox method 01-1A results - The method was adapted to wipes by folding the substrate lengthwise into 1″ folds then wrapping the folded substrate strip across the second, third and fourth fingers. One pass was made across the glass carriers. A log reduction greater than 3.0 was required to be considered passing.

[0...

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Abstract

A disinfectant formulation comprising a poly(2-ethyl-2-oxazoline) and a quaternary ammonium compound or combination of quaternary ammonium compounds is provided. A wipe having a residual biocidal property is also provided. The wipe formulation comprises a substrate comprised of a fibrous material, and the formulation present on or in the substrate. The formulation comprises a poly(2-ethyl-2-oxazoline), a quaternary ammonium compound or combination of quaternary ammonium compounds, a surfactant, water, and an optional fragrance.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application is a divisional application which claims priority from U.S. continuation-in-part application Ser. No. 15 / 625,612 filed on Jun. 16, 2017, which is a continuation-in-part application claiming priority from U.S. continuation-in-part patent application Ser. No. 15 / 162,068, filed on May 23, 2016, which claims priority from U.S. patent application Ser. No. 14 / 948962, filed on No. 23, 2015, which claims priority from U.S. provisional patent application Ser. No. 62 / 084,917, filed on Nov. 26, 2014, and from U.S. provisional patent application Ser. No. 62 / 127,075, filed on Mar. 2, 2015, and from U.S. provisional patent application Ser. No. 62 / 166,403, filed on May 26, 2015, in the United States Patent and Trademark Office. The disclosures of which are incorporated herein by reference in their entireties.FIELD OF THE INVENTION[0002]The present invention relates to the field of disinfectant formulations, and more specifically, to a d...

Claims

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Application Information

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IPC IPC(8): A01N33/12A01N25/10
CPCA01N33/12A01N25/10A01N31/08A01N31/16A01N35/02A01N37/02A01N37/36A01N43/40A01N55/00A01N59/00A01N59/02A01N59/16A01N25/34
Inventor LAN, TIANHANNA, SAMUEL JAMESSLOAN, GINA PARISEAYLWARD, BRIAN PATRICKWELCH, KAREN TERRYSHIREMAN, DENNIS EARLKAVCHOK, KEVIN ANDREWHAWES, CHARLES L.TURMENNE, JESSE DOUGLASPETKUS, MATTHEW MICHAEL
Owner MICROBAN PROD CO INC
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