7 results about "Anorexiants" patented technology

Methods and systems are provided for taking physiological marker measurements for a patient suffering from an eating disorder (e.g., anorexia nervosa, greedy nervosa, violent eating, heterophagia syndrome, ruminant disorder, or truncated food intake). Mathematical analysis of physiological marker measurements is used to create a unique personal prediction model and a unique personal data set for an individual patient, including personal prediction of the entire stage of a disorder (violence, nausea and clearance). The unique personal data set is used to diagnose and monitor specific issues of individual patients associated with eating disorders, determine the severity of the disorders, provide intraday alarms to assist in sustained disorder management or recommend treatment of specific issues of individual patients associated with these eating disorders, or predicts the outcome of a treatment for a particular problem of individual patients associated with these eating disorders.

The present invention relates to a GDNF family receptor alpha like (GFRAL)-specific antisense oligomer targeting the GFRAL gene and a pharmaceutical composition containing the same for preventing or treating obesity, diabetes, anorexia, or cachexia. It has been confirmed that the antisense oligomer according to the present invention effectively suppresses GFRAL expression in vivo and shows ameliorative effects in an animal model of cancer cachexia. Therefore, it is expected to be highly applicable as a therapeutic agent for obesity or cachexia through the suppression of GFRAL expression.

This invention belongs to the field of traditional Chinese medicine, specifically relating to a compound Chinese medicine formula for strengthening the spleen and stomach and its application in treating anorexia. The compound Chinese medicine formula of this invention consists of six medicinal and edible herbs. Fried chicken gizzard is the principal herb, invigorating the spleen, eliminating food stagnation, and promoting appetite, directly addressing the core issue of poor appetite. Hawthorn is the assistant herb, enhancing the digestive and food-eliminating effects, especially against greasy meat, while also regulating qi to relieve bloating. Codonopsis and raw yam are both adjuvant herbs, vigorously promoting digestion while also nourishing qi and yin, protecting the spleen and stomach qi, and preventing the digestive herbs from depleting qi. Poria is also an adjuvant herb, strengthening the spleen and eliminating dampness, working in conjunction with the digestive herbs to resolve stagnation and dampness from below. Pig stomach is the guiding herb, enhancing the targeted effects of harmonizing the stomach, promoting digestion, and eliminating stagnation. This compound Chinese medicine formula not only treats and improves the condition of children with anorexia but also significantly increases serum zinc and iron levels in animal models.

The application discloses a traditional Chinese medicine preparation for invigorating the spleen and stimulating appetite, and relates to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine preparation is prepared by combining various medicines, and has the functions of invigorating the spleen, stimulating appetite, and eliminating food stagnation and accumulation. According to long-term clinical use, the traditional Chinese medicine preparation has remarkable treatment effects on anorexia caused by food stagnation and accumulation and spleen deficiency, and the treatment effects are manifested as the following symptoms: poor appetite, anorexia, picky eating, abdominal distension, halitosis, frequent turning over at night, and prostration. The traditional Chinese medicine preparation is especially suitable for long-term treatment. The traditional Chinese medicine composition is safe and effective in treating food stagnation and accumulation, spleen deficiency and other symptoms by the principle of invigorating the spleen, stimulating appetite, eliminating food stagnation and accumulation.

The invention belongs to the technical field of biological medicines, and particularly relates to herbal spleen-tonifying and appetite-promoting paste for children, a preparation method, application and a product thereof. The herbal spleen-tonifying and appetite-promoting paste for children comprises hawthorn, fried malt, poria cocos, pericarpium citri reticulatae, endothelium corneum gigeriae galli, gordon euryale seed, white hyacinth bean, fructo-oligosaccharide and cattle spleen peptide, has the effects of tonifying spleen and harmonizing stomach, and promoting digestion and relieving stasis, can regulate intestinal flora and protect gastric mucosa, and is used for preventing and treating child anorexia, dyspepsia and the like. The appetizing paste is scientific in formula, simple in preparation process, good in taste and high in safety, can be prepared into various dosage forms, and has wide application prospects in the fields of health care products and medicines.

The invention relates to the technical field of medicines, and particularly discloses an amide derivative and application thereof, and the amide derivative has a compound structure as shown in a formula (I) or a formula (II). The compound provided by the invention is an MC4R antagonist with a novel structure, has nanomole-level molecular level antagonistic activity, and can be used for preparing medicines for treating cachexia and anorexia.

Provided is a Bifidobacterium lactis. The Bifidobacterium lactis is Bifidobacterium animalis subsp. lactis BL-11, and the preservation number of the Bifidobacterium animalis subsp. lactis BL-11 is CGMCC No. 20847. The provided Bifidobacterium animalis subsp. lactis can improve intestine metabolism disorder and normalize the composition of intestine microbiome so as to improve height, suppresses obesity, promote infant and youth physical development and mental development, and prevent and treat mental disorders, said mental disorders including anxiety, depression, attention-deficit / hyperactivity disorder, autism, schizophrenia, hepatic encephalopathy, anorexia, Tourette syndrome, and Asperger syndrome.