The invention provides a Cr (VI) heavy polluted soil in-situ restoration method. According to the method, firstly, a chemical reduction agent is injected into soil in situ; high-concentration Cr (VI) is subjected to primary reduction, so that the high-concentration hexavalent Cr cannot generate a toxic effect on the subsequent microorganism ecologic microbial inoculum; then, biogas residue, a carbon source and sulphate are prepared into the ecologic microbial inoculum to be injected into the Cr-containing soil in situ in a pressurizing way; by adopting a special maintenance mode, a large-scale reduction buffer belt containing sulphate reduction bacteria and sulfides is formed in the underground soil of a site; and the Cr (VI) is continuously and effectively reduced. The method has the advantages that the hexavalent Cr can be effectively reduced, and meanwhile, the cost is reduced.