Production of porous structure with biological activity on surface of pure-titanium tooth implantation

A technology of dental implants and porous structures, used in dental preparations, dental prostheses, dentistry, etc., can solve the problem that materials do not have the function of promoting or inducing osteogenesis, and achieves improved clinical success rate and good bone tissue compatibility. Effect

Inactive Publication Date: 2008-12-03
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are still some unresolved technical problems in the above-mentioned implants, mainly because the material itself does not have the function of promoting or inducing osteogenesis. After the material is implanted into the bone, it takes a long time to form an osseointegration with the bone tissue.

Method used

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  • Production of porous structure with biological activity on surface of pure-titanium tooth implantation
  • Production of porous structure with biological activity on surface of pure-titanium tooth implantation
  • Production of porous structure with biological activity on surface of pure-titanium tooth implantation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] (1) The surface of the pure titanium dental implant is sandblasted with large particles of 0.25-1.5mm emery, and the pressure is 0.4MPa, so that the surface forms an irregular rough surface with ups and downs, that is, micron-sized pits, and then placed in acetone, concentration Ultrasonic cleaning with 75% ethanol and distilled water, and drying;

[0020] (2) Use 0.09mol / L HF and 0.11mol / L HNO 3 The formed mixed solution was processed for 5 minutes, rinsed with double distilled water, and dried;

[0021] (3) Use 5.60mol / L HCl and 9.20mol / L HCl again 2 SO 4 The mixture was treated at 70°C for 40 minutes, rinsed with double distilled water, and dried;

[0022] (4) Last 8.0mol / L H 2 o 2 Treat with 0.15mol / L HCl mixture at 80°C for 20 minutes, then heat-treat at 400°C for 1.5 hours, and cool naturally to obtain a surface with a bioactive porous structure; make TiO on the surface of pure titanium 2 The layer is transformed into an anatase crystal phase structure, whic...

Embodiment 2

[0025] (1) The surface of the pure titanium dental implant is sandblasted with large particles of 0.25-1.5mm emery, and the pressure is 0.4MPa, so that the surface forms an irregular rough surface with ups and downs, that is, micron-sized pits, and then placed in acetone, concentration Ultrasonic cleaning with 75% ethanol and distilled water, and drying;

[0026] (2) Use 0.13mol / L HF and 0.07mol / L HNO 3 The formed mixed solution was processed for 15 minutes, rinsed with double distilled water, and dried;

[0027] (3) Use 6.00mol / L HCl and 8.70mol / L HCl again 2 SO 4 The mixture was treated at 90°C for 20 minutes, rinsed with double distilled water, and dried;

[0028] (4) Last 10.0mol / L H 2 o 2 Treat with 0.05mol / L HCl mixed solution at 80°C for 30 minutes, then heat-treat at 400-500°C for 0.5 hour, and cool naturally to obtain a surface with a biologically active porous structure; make TiO on the surface of pure titanium 2 The layer is converted into an anatase crystal p...

Embodiment 3

[0030] (1) The surface of the pure titanium dental implant is sandblasted with large particles of 0.25-1.5 mm emery at a pressure of 0.4 MPa, then ultrasonically cleaned in acetone, 75% ethanol, and distilled water, and dried;

[0031] (2) Use 2.75mol / L HF and 3.94mol / L HNO 3 The mixture was treated for 2 minutes, rinsed with double distilled water, and dried;

[0032] (3) Use 5.80mol / L HCl and 8.90mol / L HCl again 2 SO 4 The mixture was treated at 80°C for 30 minutes, rinsed with double distilled water, and dried;

[0033] (4) Finally, use 8.8mol / L H 2 o 2 Treat with 0.1mol / L HCl mixed solution at 80°C for 30 minutes, then heat-treat at 400°C for 1 hour. Cool naturally to obtain a surface with a bioactive porous structure (such as figure 2 shown).

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Abstract

A process for preparing the bioactive porous structure on the surface of Ti explant for tooth includes such steps as blasting sand, double acid treating, treating with H2O2 and heat treating. Its surficial TiO2 layer can induce the crystallization of hydroxy apatite, and has high compatibility to bone tissue and high successful rate.

Description

technical field [0001] The invention relates to a bioactive artificial tooth root implant, in particular to a method for preparing a bioactive porous structure on the surface of a pure titanium dental implant. Background technique [0002] For the surface structure of implants, people have made many attempts, such as smooth surface machined, rough surface sprayed with hydroxyapatite, rough surface sprayed with titanium slurry, etc., after long-term follow-up research. It has been generally accepted that implants with a rough surface and a threaded structure are more conducive to osseointegration, and the rough surface formed by sandblasting and acid etching has more advantages, which is more conducive to guiding osteoblast chemotaxis than the rough surface formed by spraying. Accelerates osseointegration. [0003] Branemark implants produced by Norbel-pharma in Sweden and Implant surface with TiUnite TM Surface (porous titanium oxide structure) or hydroxyapatite coating ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61C8/00A61C13/00A61K6/00
Inventor 何福明陈松赵姗姗王小祥赵士芳
Owner ZHEJIANG UNIV
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