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Medicinal composition for treating and preventing nasal sinusitis and preparing method

A composition and technology for sinusitis, applied in the field of traditional Chinese medicine, can solve the problems of improving curative effect, lack of pertinence of syndrome types, disadvantages, etc.

Inactive Publication Date: 2009-01-14
北京东方绿原科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese patents such as the sinusitis rehabilitation capsule described in CN00105277 have fragrance to open the orifices, dispel wind and relieve pain, clear turbidity and remove dampness, detoxify and expel pus, etc. , CN96115696, CN95110416, CN96100733, CN93117300, CN93100869, etc., the functions and indications described in these prescriptions rule a variety of nasal diseases, and seldom use TCM classification to treat them. Instead, various syndrome types of sinusitis are included in one In the compound prescription, there is a lack of pertinence of syndrome types, and most of them are based on wind-heat excess syndrome, which is not conducive to improving the curative effect. The prescription overcomes the one-sidedness of previous drugs for the treatment of sinusitis based on empirical evidence, provides a pure Chinese medicine compound composition and preparation process with definite curative effect, safety and convenience, small side effects, and low price, and makes up for the current treatment of gallbladder depression and heat. Insufficiency of fewer drugs for sinusitis

Method used

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  • Medicinal composition for treating and preventing nasal sinusitis and preparing method
  • Medicinal composition for treating and preventing nasal sinusitis and preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] Example 1: Preparation of tablets of the drug of the present invention

[0054] 6 parts of Gentian, 4.5 parts of Scutellaria

[0055] Fist Ginseng 4.5 parts Red Peony 4.5 parts

[0056] Forsythia 4.5 parts Oldenlandia diffusa 4.5 parts

[0057] Preparation Process:

[0058] (1) Scutellaria baicalensis Georgi is decocted twice with water, 8 times the amount each time, 1 hour each time, the water extract is concentrated, the pH value of acid is adjusted to 1-2, keep warm, stand still, precipitation water, alcohol or alkaline water, alkaline alcohol solution Wash to pH 7, vacuum dry, pulverize into fine powder to obtain Scutellaria baicalensis extract;

[0059] (2) Forsythia suspense was steam distilled to extract the volatile oil for 8 hours. The distilled water extract was collected in another device. The volatile oil was clathrated with 10 times the amount of β-cyclodextrin, dried at low temperature, and pulverized to obtain fine clathrate powder for use; The above-mentione...

Embodiment 2

[0061] Example 2: Preparation of granules of the drug of the present invention

[0062] 4 parts of gentian, 3 parts of scutellaria,

[0063] 3 copies of Fist Ginseng 3 copies of Red Peony

[0064] 3 parts of Forsythia, 4 parts of Oldenlandia diffusa

[0065] 3 servings of Xin Yi 3 servings of Angelica root

[0066] Preparation Process:

[0067] (1) Scutellaria baicalensis Georgi was decocted with water for 3 times, 10 times the amount each time, 1.5 hours for the first time, 1 hour for the second time, and 0.5 hours for the third time. The water extract was concentrated, the pH value was adjusted to 1-2 by acid, and the temperature was kept warm. At rest, the precipitation is washed with water, alcohol or alkaline water, alkaline alcohol solution to pH 7, vacuum dried, pulverized into fine powder to obtain Scutellaria baicalensis extract;

[0068] (2) Forsythia and Xinyi, steam distillation to extract the volatile oil for 7 hours, the distilled water extract is collected in anothe...

Embodiment 3

[0070] Example 3: Preparation of capsules of the drug of the present invention

[0071] 4 parts of gentian, 3 parts of scutellaria

[0072] 3 copies of Fist Ginseng 3 copies of Red Peony

[0073] 3 parts of Forsythia, 4 parts of Oldenlandia diffusa

[0074] 3 servings of Xin Yi 3 servings of Angelica dahurica

[0075] (1) Scutellaria baicalensis Georgi was decocted with water for 3 times, 10 times the amount each time, 1.5 hours for the first time, 1 hour for the second time, and 0.5 hours for the third time. The water extract was concentrated, the pH value was adjusted to 1-2 by acid, and the temperature was kept warm. At rest, the precipitation is washed with water, alcohol or alkaline water, alkaline alcohol solution to pH 7, vacuum dried, pulverized into fine powder, to obtain Scutellaria baicalensis Georgi extract;

[0076] (2) Forsythia and Xinyi, steam distillation to extract the volatile oil for 7 hours, the distilled water extract is collected in another device, the volat...

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Abstract

The medicinal composition for preventing and treating nasal sinusitis is prepared with gentian, skullcap root, bistort rhizome, red peony root, forsythia and oldenlandia in certain weight proportion. It may be prepared into different forms, and has determined curative effect, high safety, less side effect and low cost.

Description

Technical field: [0001] The invention relates to a pharmaceutical composition for preventing and treating sinusitis and a preparation method thereof, and belongs to the field of traditional Chinese medicine. Background technique: [0002] Sinusitis is a common and frequently-occurring disease in otolaryngology. Acute sinusitis is an acute inflammation of the mucous membrane of the sinuses. Acute rhinitis is often secondary. Acute sinusitis can also be secondary to allergic rhinitis, or both. The pathogenic bacteria of this disease are mostly pyogenic cocci, as well as pneumococcus, streptococcus, staphylococcus, as well as Escherichia coli, Proteus and influenza bacillus, and most acute sinusitis is a mixed infection. At present, western medicine treatment methods are mostly systemic application of antibiotics. Due to the widespread use of antibiotics, the drug resistance of pathogenic bacteria increases, so the efficacy of antibiotics is declining. Therefore, it is more effectiv...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/515A61K36/59A61K36/704A61K36/71A61K36/634A61K36/74A61K9/10A61K9/14A61K9/12A61K9/20A61K9/70A61K9/72A61P11/02
Inventor 何骋
Owner 北京东方绿原科技发展有限公司
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