Medicine composition contg. isatis root and scutellariae glucoside

A technology of isatis root extract and composition, which is applied in the field of medicine and achieves the effects of simple preparation process, less impurities and definite curative effect

Inactive Publication Date: 2009-04-29
海安江理工技术转移中心有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, using the interaction between Radix isatidis or its extract and baicalin, compatible prescriptions for antibacterial, antiviral and other drugs have not been reported yet.

Method used

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  • Medicine composition contg. isatis root and scutellariae glucoside
  • Medicine composition contg. isatis root and scutellariae glucoside
  • Medicine composition contg. isatis root and scutellariae glucoside

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0138] Example 1 Preparation of Radix Radix Radix Extract

[0139] Preparation method of isatidis extract

[0140] Take Radix Radix, crush it into coarse powder, add water and decoct twice, the first time for 2 hours, and the second time for 1 hour, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.15-1.20 concentrate, add 1% hydrochloric acid to adjust When the pH value reaches 5-6, add it to a strongly acidic cation exchange resin column, add 2 times the amount of water to flush the column, discard the flushing solution, add 1% ammonia test solution to the column, collect the eluent, and then add 1% hydrochloric acid Adjust the pH value to 7-7.5, let stand overnight, filter, concentrate, and dry to obtain the product.

[0141] Identification experiment of Banlangen extract

[0142] Take 0.1g of this product, add 10ml of ethanol, sonicate for 15min, evaporate to dryness, add 1ml of ethanol to the residue to dissolve, and use it as the ...

Embodiment 2

[0149] Example 2 Preparation of Banhuang Composition Powder Injection

[0150] 1. Prescription:

[0151] Prescription 1

[0152]

[0153] Prescription 2

[0154]

[0155] Prescription 3

[0156]

[0157] 2. Specific steps:

[0158] 1) First, aseptically treat the containers used for liquid preparation, antibiotic glass bottles, rubber stoppers, etc.

[0159] 2) Weigh the raw materials and auxiliary materials according to the prescription quantity.

[0160] 3) Take 40% water for injection and add the prescribed amount of Radix isatidis extract, heat and stir to dissolve completely. Add a small amount of water for injection to baicalin, dissolve it with appropriate amount of sodium hydroxide after heating. Combine the above solutions, then add mannitol, heat and stir to dissolve completely, and add sterile water for injection to the full amount.

[0161] 4) Add activated carbon for needles with a dosing volume of 0.1%, heat and stir for 15 minutes.

[0162] 5)...

Embodiment 3

[0168] Example 3 Preparation of Banhuang Composition Aqueous Injection

[0169] 1. Prescription:

[0170] Prescription 1

[0171]

[0172] Prescription 2

[0173]

[0174] Prescription 3

[0175]

[0176] 2. Specific steps:

[0177] 1) Dispose of the pipes and containers used for liquid preparation one day in advance, and rinse them with fresh water for injection before use.

[0178] 2) Take water for injection with a dosing volume of 40%, add the Radix Radix Radix extract in the prescription volume, heat and stir to dissolve completely. Add a small amount of water for injection to baicalin, dissolve it with appropriate amount of sodium hydroxide after heating.

[0179] 3) Combine the above solutions and add water for injection to the full amount.

[0180] 4) Add activated carbon for needles with a dosing volume of 0.1%, heat and stir for 15 minutes.

[0181] 5) Decarburization by sand filter stick filtration. Measure and adjust the pH of the solution.

[0...

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Abstract

An antibacterial and antiviral composite medicine for antipyresis and analgesia is proportionally prepared from isatis root or its extract and scutelloside. It has high synergistic effect and high stability.

Description

1. Technical field [0001] The invention belongs to the technical field of medicine, and relates to a pharmaceutical composition for antibacterial, antiviral, antipyretic and analgesic, a preparation method and preparation thereof, and a composition of raw materials of medicinal components contained in the pharmaceutical composition For: Radix isatidis or its extract and baicalin. 2. Background technology [0002] Due to the current spread of resistance to many traditional antibiotics such as penicillin and amoxicillin has attracted great attention and attention from the medical community, the emergence of a large number of multi-drug resistant strains and the emergence of new viruses have made refractory infections more and more common. more. At the same time, since the compatibility of natural medicines such as traditional Chinese herbal medicines or the composition of active ingredients often have complementary and synergistic effects, and do not produce drug resistance, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/539A61K36/19A61K36/315A61K31/7048A61P31/04A61P31/12A61P29/00
Inventor 黄振华
Owner 海安江理工技术转移中心有限公司
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