Unlock instant, AI-driven research and patent intelligence for your innovation.

Ultramicro chito polysaccharide product processing method

A technology of chitosan and a processing method, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, and organic active ingredients, etc., can solve the problems of unstable anti-cancer and anti-cancer effects, and achieve stable effects and high targets. Affinity effect, the effect of increasing the absorption rate

Inactive Publication Date: 2009-12-23
NINGBO SCIENTZ BIOTECH
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the particle size of the existing chitosan products is basically greater than 2 μm, and it is found that the anti-cancer effect is not very stable.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] Example 1: Select 2 kg of chitosan solid particles with a particle diameter of 2 μm as a raw material and place it in a material vat; add 20 kg of white vinegar to the material vat to impregnate the raw material and stir to mix, then add water to the material vat to reach the pH value 6; under the process conditions of temperature 20°C, ultrasonic frequency 60 kHz, and ultrasonic power 800W, according to the volume of liquid in the material tank, the processing time per unit volume of liquid is 10 seconds / ml with ultrasonic processing equipment Ultrasonic micronization treatment is performed on the liquid in the material tank to obtain a transparent liquid product with a chitosan content of 10 mg / ml and a chitosan particle diameter of 0.25 nanometers.

Embodiment 2

[0010] Embodiment 2: Select 3 kilograms of chitosan solid particles with a particle diameter of 20 μm as raw materials and place them in a material tank; add 60 kilograms of white vinegar to the material tank to impregnate the raw materials and stir to mix, then add water to the material tank to pH value is 5; under the process conditions of temperature 30°C, ultrasonic frequency 20 kHz, and ultrasonic power 200W, according to the volume of liquid in the material tank, the processing time per unit volume of liquid is 5 seconds / ml with ultrasonic processing equipment Ultrasonic micronization treatment is performed on the liquid in the material tank to obtain a transparent liquid product with a chitosan content of 2 mg / ml and a chitosan particle diameter of 15 nanometers.

Embodiment 3

[0011] Example 3: Select 2 kg of chitosan solid particles with a particle diameter of 200 μm as a raw material, and place it in a material vat; add 100 kg of white vinegar to the material vat to impregnate the raw material and stir to mix, then add water to the material vat until the pH value 3; under the process conditions of temperature 10°C, ultrasonic frequency 100 kHz, and ultrasonic power 1800W, according to the volume of liquid in the material tank, the processing time per unit volume of liquid is 15 seconds / ml with ultrasonic processing equipment Ultrasonic micronization is performed on the liquid in the material tank to obtain a transparent liquid product with a chitosan content of 20 mg / ml and a chitosan particle diameter of 100 nanometers.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
diameteraaaaaaaaaa
particle diameteraaaaaaaaaa
Login to View More

Abstract

The invention discloses an ultramicronized chitosan product and a processing method thereof. The chitosan solid particle with a particle diameter of less than 200 μm is selected as a raw material, and edible vinegar is added to impregnate the raw material at a weight ratio of 10-50:1 and stirred. Mix, then add water until the pH value is 3-6, and the treatment time per unit volume of liquid is 2- Ultrasonic micronization of the liquid at 15 seconds / ml to obtain a transparent liquid product with a chitosan content of 0.1-20 mg / ml and a chitosan particle diameter of 0.25-100 nanometers, and further treatment can also be obtained containing A white powdery chitosan product with a water content of 1%-8%, the chitosan product processed by the method of the present invention can effectively improve the absorption rate of the active ingredients of the product by the human body, and improve the anti-cancer and anti-cancer aspects. effect and stability.

Description

technical field [0001] The invention relates to a chitosan product, in particular to a processing method for an ultramicronized chitosan product. Background technique [0002] Chitosan is the second largest carbon source in nature after cellulose. Chitosan is not only an abundant carbon source that can be utilized, but also plays an important role in the interaction between organisms and organisms. Therefore, the research on chitosan at home and abroad is very active, and there are many reports on the research results of chitosan. According to the Chinese patent documents, the current research on chitosan mainly includes: A: on chitosan Structural form of sugar, amino acid sequence; B: extraction method of chitosan and its derivatives, C: development and utilization of chitosan and its derivatives, D: microorganisms containing chitosan components, native Method E for the prevention and control of pests, worms, etc. harm to animals and plants: use the characteristics of chit...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C08B37/08C08J3/12A61K31/722A61P35/00
Inventor 肖长锦
Owner NINGBO SCIENTZ BIOTECH