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Hard medicine capsule

A technology of capsules and drugs, applied in the field of hard drug capsules and preparations, can solve the problems of gelatin capsules sensitive to changes in temperature and humidity, hidden dangers of animal protein safety, inconvenient transportation and storage, etc., to improve self-immunity, not easy to break, Ease of transport and storage

Inactive Publication Date: 2007-07-18
刘杰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Traditional hollow capsule production raw materials are medicinal gelatin, medicinal gelatin belongs to animal protein, but animal protein has potential safety hazards; in addition, gelatin capsules are sensitive to changes in temperature and humidity, and if the temperature and humidity are not properly controlled, they are easy to break and are not easy to transport and storage

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] The active ingredients of the hard drug capsules of the present invention are composed of: 35% by weight of hydroxypropyl methylcellulose; 55% of hydroxypropyl starch; 10% of chitin; and the technological process of making the capsule is: preparing an aqueous solution. The concentration of the aqueous solution is 10%; the viscosity of the aqueous solution is 1000 centipoise; the aqueous solution is allowed to stand or depressurize to completely degas in the gel tank, preheat the shaft needle to 70℃ before immersing the liquid, then immerse it in the aqueous solution with a heating temperature of 40℃, and place it for 2 Minutes; take out the shaft needle and dry it in a closed drying box at a drying temperature of 30°C; form a hard shell-like polymer blend film on the shaft needle, pull out the shaft needle after demolding, and make it after trimming Hard drug capsule shell;

[0013] The capsule sleeve adopts a shaft needle with a diameter larger than the capsule shell to pr...

Embodiment 2

[0017] The active ingredients of the hard drug capsules of the present invention are composed of 40% by weight of hydroxypropyl methylcellulose; 47% of hydroxypropyl starch; 13% of chitin; and the technological process of making the capsule is: preparing an aqueous solution. The concentration of the aqueous solution is 20%; the viscosity of the aqueous solution is 5000 centipoise; the aqueous solution is allowed to stand or depressurize to completely degas in the gel tank, preheat the shaft needle to 75℃ before immersing the liquid, then immerse it in the aqueous solution with heating temperature of 50℃, and place 2 Minutes; take out the shaft needle and dry it in a closed drying box at a drying temperature of 35°C; form a hard shell-like polymer blend film on the shaft needle, pull out the shaft needle after demolding, and make it after trimming Hard drug capsule shell;

[0018] The capsule sleeve adopts a shaft needle with a diameter larger than the capsule shell to prepare an a...

Embodiment 3

[0022] The active ingredients of the hard drug capsules of the present invention are composed of: 45% by weight of hydroxypropyl methylcellulose; 40% of hydroxypropyl starch; 15% of chitin; and the technological process of capsule manufacturing is: preparing an aqueous solution. The concentration of the aqueous solution is 30%; the viscosity of the aqueous solution is 10000 centipoise; the aqueous solution is allowed to stand or depressurize to completely degas in the glue tank, and the shaft needle is preheated to 80℃ before immersing the liquid, then immersed in the aqueous solution with a heating temperature of 60℃, and placed 2 Minutes; Take out the shaft needle and dry it in a closed drying box at a drying temperature of 55°C; form a hard shell-like polymer blend film on the shaft needle, pull out the shaft needle after demolding, and make it after trimming Hard drug capsule shell;

[0023] The capsule sleeve adopts a shaft needle with a diameter larger than the capsule shell...

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Abstract

An empty capsule for medicines is proportionally prepared from hydroxypropyl methylcellulose, hydroxypropyl starch and chitin through preparing aqueous solution, immersing die in it, baking, removing die and trimming. It has bactericiding action.

Description

Technical field [0001] The invention relates to a hollow capsule, in particular to a hard medicine capsule made of pure plant cellulose as the main raw material and a preparation method. Background technique [0002] The traditional hollow capsule production raw material is medicinal gelatin. The medicinal gelatin belongs to animal protein, but animal protein has potential safety hazards. In addition, gelatin capsules are sensitive to changes in temperature and humidity, and the temperature and humidity are not properly controlled. They are easy to break and inconvenient to transport. And storage. At present, there are records of producing hollow capsules with starch and konjac glucomannan, as well as cellulose hollow capsules made from plant cellulose as the main raw material. Summary of the invention [0003] The purpose of the present invention is to provide a hard pharmaceutical capsule prepared with pure plant cellulose as the main raw material. [0004] The plant capsule o...

Claims

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Application Information

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IPC IPC(8): A61K9/48A61K47/38A61J3/07
Inventor 刘杰高玉宁
Owner 刘杰
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