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Traditional Chinese medicine composition tablet for treating gastrointestinal disease and its preparing method

A technology for gastrointestinal diseases and compositions, which are applied in the field of traditional Chinese medicine compositions for treating gastrointestinal diseases and their preparation fields, and can solve the problems of bad smell, reduced dissolution rate and absorption rate, low effective ingredients and the like

Active Publication Date: 2007-07-18
GUANGZHOU WANGLAOJI PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The Bao Chai Pills recorded in the Pharmacopoeia adopts the production method of "crushing various medicinal materials, pan-pilling, and coating", which leads to the low active ingredients of the drug in Bao Chai Pills, reduced dissolution rate and absorption rate in the gastrointestinal tract, and prolonged absorption time , the onset of effect is slow, and the bad smell of Po Chai Pills will make patients resist

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0219] a. Take prescription 1: Uncaria 15.50g, Magnolia officinalis 80.40g, Trichosanthes 55.50g, Poria 155.60g, Angelica dahurica 80.40g, Guangdong Divine Comedy 80.40g, Tribulus terrestris 15.50g, Cangzhu 80.40g, Pueraria 80.40g, Huajuhong 36.70g, 55.50g of rice buds, 36.70g of chrysanthemum, 80.40g of woody fragrance, 80.40g of patchouli, 36.70g of mint, 95.20g of coix seed for later use;

[0220] b. Take the 6 flavors of woody, patchouli, magnolia officinalis, atractylodes rhizome, angelica, and mint, grind them into coarse powder, and place them in the extractor of the supercritical CO2 device for extraction to obtain the extract; mix the extracts, add 6.5 Cyclodextrin inclusion complex with twice the amount of the extract is obtained to obtain cyclodextrin inclusion compound, which is used for later use; medicinal residues are combined together, and ultrasonically extracted at a temperature of 65-70°C, extracted twice, each time for 2.5 hours; filtered to obtain ultrasoni...

Embodiment 2

[0223] a. Take prescription 2: Uncaria 55.80g, Magnolia officinalis 215.50g, Trichosanthes 205.80g, Poria 423.20g, Angelica dahurica 215.50g, Guangdong Divine Comedy 215.50g, Tribulus terrestris 55.80g, Atractylodes 215.50g, Pueraria 215.50g, Huajuhong 125.40g, 205.80g of rice buds, 125.40g of chrysanthemum, 215.50g of woody fragrance, 215.50g of patchouli, 125.40g of peppermint, 324.80g of coix seed;

[0224] b. Take the 6 flavors of woody, patchouli, magnolia officinalis, atractylodes rhizome, angelica dahurica, and peppermint, grind them into coarse powder, and place them in the extractor of the supercritical CO2 device for extraction to obtain the extract; mix the extracts, add 5 Cyclodextrin inclusion complex with twice the amount of extract is obtained to obtain cyclodextrin inclusion complex, which is used for later use; medicinal residues are combined together, and ultrasonically extracted at a temperature of 50-60°C, extracted twice, each time for 3 hours; filtered to ...

Embodiment 3

[0227] a. Take prescription three: Uncaria 15.50g, Magnolia officinalis 215.50g, Trichosanthes 55.50g, Poria 155.60g, Angelica dahurica 215.50g, Guangdong Divine Comedy 215.50g, Tribulus terrestris 55.80g, Atractylodes 215.50g, Pueraria 215.50g, Huajuhong 125.40g, 205.80g of rice buds, 125.40g of chrysanthemum, 215.50g of woody fragrance, 215.50g of patchouli, 125.40g of peppermint, 95.20g of coix seed for later use;

[0228] b. Take the 6 flavors of woody, patchouli, magnolia officinalis, atractylodes rhizome, angelica dahurica, and peppermint, grind them into coarse powder, place them in the extractor of the supercritical CO2 device to extract, and obtain the extract; mix the extract, add 3 Cyclodextrin inclusion complex with twice the amount of extract is obtained to obtain cyclodextrin inclusion compound, which is used for later use; medicinal residues are combined together, and ultrasonically extracted at a temperature of 85-90°C, extracted 3 times, each time for 2 hours; ...

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PUM

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Abstract

A Chinese medicine in the form of tablet for treating gastrointestinal disease is prepared from 16 Chinese-medicinal materials including uncaria stem with hooks, magnolia bark, trichosanthes root, tuckahoe, etc. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition for treating gastrointestinal diseases and a preparation method thereof. Background technique [0002] Abdominal pain, diarrhea, choking and acid, nausea and vomiting, gastrointestinal discomfort, indigestion, seasickness, seasonal cold, fever and headache are common clinical symptoms. These symptoms can be caused by many reasons. Gastrointestinal diseases can also be seen with external colds It is one of the main reasons. These symptoms were recorded in the "Taiping Huimin Heji Jufang" in the Song Dynasty, and Huoxiangzhengqi Fang was provided as a prescription for treatment. Huoxiang Zhengqi Prescription has been hailed as the "sacred medicine for summer heat and dampness" by doctors of all dynasties. This prescription has the effects of relieving the exterior, dispelling dampness, and harmonizing the middle. It is often used clinically to tr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/20A61P1/14A61P1/08
Inventor 李祖泽施少斌郑荣波沈军黄晓丹
Owner GUANGZHOU WANGLAOJI PHARM CO LTD